Skeletal muscle blood flow after prolonged tourniquet ischaemia and reperfusion with and without intervening reoxygenation: An experimental study in rats using laser Doppler perfusion imaging

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery

Volumn 33, Issue 3, 1999, Pages 281-285

  Sirsjö, Allan ^a,c   Gidlöf, Anders ^a   Nilsson, Gert ^a   Povlsen, Bo ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Blood flow; Ischaemia; Laser Doppler; Reperfusion; Skeletal muscle

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; LASER FLOWMETER; MALE; MUSCLE BLOOD FLOW; MUSCLE ISCHEMIA; NONHUMAN; RAT; REOXYGENATION; REPERFUSION; REPERFUSION INJURY; TOURNIQUET;

ANIMALS; HINDLIMB; ISCHEMIA; LASER-DOPPLER FLOWMETRY; MALE; MUSCLE, SKELETAL; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION; REPERFUSION INJURY; STATISTICS, NONPARAMETRIC; TIME FACTORS; TOURNIQUETS;

EID: 5944251618     PISSN: 02844311     EISSN: None     Source Type: Journal    
DOI: 10.1080/02844319950159244     Document Type: Article

References (28)

1. 1. Bagge U, Amundson B, Lauritzen C. White blood cell deformability and plugging of skeletal muscle capillaries in hemorrhagic shock. Acta Physiol Scand 1980; 108: 159-163.
2. 2. Braide M, Amundson B, Chien S, Bagge U. Quantitative studies on the influence of leukocyte on the vascular resistance in a skeletal muscle preparation. Microvasc Res 1984; 27: 331-352.
3. 3. Choudhury NA, Sakaguchi SS, Koyano K, Matin AFM, Muro H. Free radical injury in skeletal muscle ischemia and reperfusion. J Surg Res 1991; 51: 392-398.
4. 4. Diana JN, Laughlin MH. Effect of ischemia on capillary pressure and equivalent pore radius in capillaries ot the isolated dog hind limb. Circ Res 1974; 35: 77-101.
5. 5. Gidlöf A, Lewis DH, Hammersen F. The effect of prolonged total ischemia on the ultrastructure of human skeletal muscle capillaries. A morphometric analysis. Int J Microcirc Clin Exp 1988; 7: 67-86.
6. 6. Gidlöf A, Lewis DH. The relation of the postischemic reperfusion impairment to the severity of ischemia in the tibials anterior muscle of the rat. Int J Microcirc Clin Exp 1990; 9: 187-203.
7. 7. Green PG. Operative hand surgery. 3rd ed. New York: Churchill Livingstone, 1993: 6-7.
8. 8. Haddy FJ, Scott JB. Active hyperemia, reactive hyperemia, and autoregulation of blood flow. In: Kaley G, Altura BM, eds. Microcirculation. Baltimore: University Park Press, 1978: 531-554.
9. 9. Harman JW. The significance of local vascular phenomena in the production of ischemic necroses in skeletal muscle. Am J Pathol 1948; 24: 625-641.
10. 10. Iadecola C. Bright and dark sides of nitric oxide in ischaemic brain injury. Trends Neurosci 1997; 20: 132-129.
11. 11. Idström JP, Soussi B, Elander A, Bylund-Fellenius AC. Purine metabolism after in vivo ischemia and reperfusion in rat skeletal muscle. Am J Physiol 1990; 258: 1668-1673.
12. 12. Kawasaki S, Sugiyama S, Ishiguro N, Ozawa T, Miura T. Implication of super-oxide radicals on ischemia-reperfusion-induced skeletal muscle injury in rats. Eur Surg Res 1993; 25: 129-136.
13. 13. Korthuis RJ, Granger DN, Townsley MI, Taylor AE. The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability. Circ Res 1985; 7: 599-609.
14. 14. Korthuis RJ, Grisham MB, Granger DN. Leukocyte depletion attenuates vascular injury in postischemic skeletal muscle. Am J Physiol 1988; 254: 823-827.
15. 15. Linden M, Sirsjö A, Nilsson GE, Lindbom L, Gidlöf A. Laser Doppler perfusion imaging for blood flow assessment in the rabbit tenuissimus muscle. Am J Physiol 1995; 269: H1496-H1500.
16. 16. Mandel LJ, Takano T, Soltoff SP, Murdough S. Mechanisms whereby exogenous adenine nucleotides improve rabbit renal proximal function during and after anoxia. J Clin Invest 1988; 81: 1255-1264.
17. 17. Martin WJ. Neutrophils kill pulmonary endothelial cells by a hydrogen-peroxide-dependent pathway. An in vitro model of neutrophil-mediated lung injury. Am Rev Respir Dis 1984; 130: 209-213.
18. 18. Menger MD, Pelikan S, Steiner D, Messmer K. Microvascular ischemia/reperfusion injury in striated muscle: significance of "Reflow Paradox". Am J Physiol 1992; 263: 1901-1906.
19. 19. Schmid-Schoenbein GW. The damaging potential of leukocyte activation in the microcirculation. Angiology 1993; 44: 45-56.
20. 20. Sirsjö A, Lewis DH, Nylander G. The accumulation of polymorphonuclear leukocytes in postischemic skeletal muscle in the rat, measured by quantitating tissue myeloperoxidase. Int J Microcirc Clin Exp 1990; 9: 163-173.
21. 21. Sirsjö A, Söderkvist P, Gustafsson U, Lewis DH, Nylander G. The relationship between blood flow, development of edema and leukocyte accumulation in post-ischemic rat skeletal muscle. Microcirc Endothelium Lymphatics 1990: 21-33.
22. 22. Sternbergh WC, Makhoul RG, Adelman B. Nitric oxide-mediated, endothelium-dependent vasodilation is selectively attenuated in the postischemic extremity. Surgery 1993; 114: 960-967.
23. 23. Stompro BE, Stevenson TR, Winecinger MA, Sharman RB, Carlsen RC. A reperfusion interval reduces the contractility deficit in skeletal muscle following tourniquet ischemia. Plast Reconstr Surg 1994; 94: 1003-1011.
24. 24. Strock PE, Majno G. Vascular responses to experimental tourniquet ischemia. Surg Gynecol Obstet 1969; 129: 309-318.
25. 25. Stromski ME, Cooper K, Thulin G, Gaudio KM, Siegel NJ, Shulman RG. Chemical and functional correlates of post-ischemic renal ATP levels. Proc Natl Acad Sci U S A 1986; 83: 6142-6145.
26. 26. Summers ST, Zinner MJ, Freischlag JA. Production of endothelium-derived relaxing factor (EDRF) is compromised after ischemia and reperfusion. Am J Surg 1993; 166: 216-220.
27. 27. Weiss SJ, Young J, LoBuglio AF, Slivka A, Nimek NF. Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells. J Clin Invest 1981; 68: 714-721.
28. 28. Wårdell K, Jakobsson A, Nilsson GE. Laser Doppler perfusion imaging by dynamic light scattering. IEEE Trans Biomed Eng 1993; 40: 309-316.