Analysis of the relationship of leptin, high-sensitivity C-reactive protein, adiponectin, insulin, and uric acid to metabolic syndrome in lean, overweight, and obese young females

Metabolic Syndrome and Related Disorders

Volumn 7, Issue 1, 2009, Pages 17-22

  Abdullah, Abdul Ridha ^a   Hasan, Haydar A ^a   Raigangar, Veena L ^a  

^a UNIVERSITY OF SHARJAH   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; LEPTIN; LOW DENSITY LIPOPROTEIN; URIC ACID; ADIPOQ PROTEIN, HUMAN; BIOLOGICAL MARKER;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLOOD PRESSURE; BODY MASS; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; METABOLIC SYNDROME X; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE; ADOLESCENT; BLOOD; BODY WEIGHT; CROSS-SECTIONAL STUDY; EARLY DIAGNOSIS; PREDICTIVE VALUE; UNITED ARAB EMIRATES; UPREGULATION; YOUNG ADULT;

ADIPONECTIN; ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BODY MASS INDEX; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; EARLY DIAGNOSIS; FEMALE; HUMANS; INSULIN; LEPTIN; METABOLIC SYNDROME X; OBESITY; OVERWEIGHT; PREDICTIVE VALUE OF TESTS; THINNESS; UNITED ARAB EMIRATES; UP-REGULATION; URIC ACID; WAIST CIRCUMFERENCE; YOUNG ADULT;

EID: 59349107959     PISSN: 15404196     EISSN: None     Source Type: Journal    
DOI: 10.1089/met.2008.0045     Document Type: Article

References (33)

1. Carter AO, Saadi HF, Reed RL, Dunn EV. Assessment of obesity, lifestyle, and reproductive health needs of female citizens of Al Ain, United Arab Emirates. J Health Populat Nutrit 2004;22:75-83.
2. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-3421.
3. Ballantyne CM, Hoogeveen RC, McNeill AM, Heiss G, Schmidt MI, Duncan BB, Pankow JS. Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study. Int J Obes 2008;32(suppl 2):S21-S24.
4. Patel SB, Reams GP, Spear RM, Freeman RH, Villarreal D. Patel SB, Reams GP, Spear RM, Freeman RH, Villarreal D. Leptin: linking obesity, the metabolic syndrome, and cardiovascular disease. Curr Hypertens Rep 2008;10:131-137.
5. Rifai N, Ridker PM. High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. Clin Chem 2001;47:403-411.
6. Ukkola O, Kesäniemi YA. Leptin and high-sensitivity C-reactive protein and their interaction in the metabolic syndrome in middle-aged subjects. Metabolism 2007;56:1221-1227.
7. Marx N, Walcher D. C-Peptide and atherogenesis: C-peptide as a mediator of lesion development in patients with type 2 diabetes mellitus? Exp Diabetes Res 2008;2008: DOI: 10.1155/2008/38510:ID:385108.
8. Zhou LB, Chen MD. Adipokine and metabolic syndrome. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2006;28:840-844.
9. Okamoto Y, Kihara S, Funahashi T, Matsuzawa Y, Libby P. Adiponectin: a key adipocytokine in metabolic syndrome. Clin Sci 2006;110:267-278.
10. Kressel G, Trunz B, Bub A, Hülsmann O, Wolters M, Lichtinghagen R, Stichtenoth DO, Hahn A. Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis 2008;Apr 20. DOI: 10.1016/J.ATHEROSCLEROSIS.2008.04.012.
11. Ford ES, Li C, Cook S, Choi HK. Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents. Circulation 2007;115: 2526-2532.
12. Huang TT, Shimel A, Lee RE, Delancey W, Strother ML. Metabolic risks among college students: prevalence and gender differences. Metab Syndr Relat Disord 2007;5:365-372.
13. Panarotto D, Ardilouze JL, Tessier D, Maheux P. The degree of hyperinsulinemia and impaired glucose tolerance predicts plasma leptin concentrations in women only: a new exploratory paradigm. Metabolism 2000;49:1055-1062.
14. Lichnovská R, Gwozdziewiczová S, Chlup R, Hrebícek J. Serum leptin in the development of insulin resistance and other disorders in the metabolic syndrome. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005;149:119-126.
15. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985,28:412-419.
16. Gulturk S, Cetin A, Erdal S. Association of leptin with insulin resistance, body composition, and lipid parameters in postmenopausal women and men in type 2 diabetes mellitus. Saudi Med J 2008;29:813-820.
17. Havel PJ, Kasim-Karakas S, Mueller W, Johnson PR, Gingerich RL, Stern JS. Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab 1996;81:4406-4413.
18. Wu DM, Chu NF, Shen MH, Wang SC. Obesity, plasma high sensitivity C-reactive protein levels and insulin resistance status among school children in Taiwan. Clin Biochem 2006;39:810-815.
19. Wu DM, Chu NF, Shen MH, Chang JB. Plasma C-reactive protein levels and their relationship to anthropometric and lipid characteristics among children. J Clin Epidemiol 2003J;56:94-100.
20. Best LG, Zhang Y, Lee ET, Yeh JL, Cowan L, Palmieri V, Roman M, Devereux RB, Fabsitz RR, Tracy RP, Robbins D, Davidson M, Ahmed A, Howard BV. C-reactive protein as a predictor of cardiovascular risk in a population with a high prevalence of diabetes: the Strong Heart Study. Circulation 2005;112:1289-1295.
21. Ingelsson E, Hulthe J, Lind L. Inflammatory markers in relation to insulin resistance and the metabolic syndrome. Eur J Clin Invest 2008;May 16. (in press). DOI: 10.1111/J.1365-2362.2008.01962.
22. Oda E. C-reactive protein as an optional component of metabolic syndrome. Metabolism 2006;55:1558; author reply 1558-1559.
23. Kim C, Park J, Park J, Kang E, Ahn C, Cha B, Lim S, Kim K, Lee H. Comparison of body fat composition and serum adiponectin levels in diabetic obesity and non-diabetic obesity. Obesity 2006;14:1164-1171.
24. Santaniemi M, Kesäniemi YA, Ukkola O. Low plasma adiponectin concentration is an indicator of the metabolic syndrome. Eur J Endocrinol 2006;155:745-750.
25. Ferrannini E, Haffner SM, Mitchell BD, Stern MP. Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 1991;34:416-422.
26. Lim SC, Tan BY, Chew SK, Tan CE. The relationship between insulin resistance and cardiovascular risk factors in overweight/obese non-diabetic Asian adults: the 1992 Singapore National Health Survey. Int J Obes Relat Metab Disord 2002;26:1511-1516.
27. Lender D, Arauz-Pacheco C, Adams-Huet B, Raskin P. Essential hypertension is associated with decreased insulin clearance and insulin resistance. Hypertension 1997;29(1 Pt 1):111-114.
28. Vanhala MJ, Pitkäjärvi TK, Keinänen-Kiukaanniemi SM, Kumpusalo EA, Takala JK. Hyperinsulinaemia in hypertensive subjects: validity of a test for the detection of insulin resistance in clinical practice. J Hum Hypertens 1998;12:463-467.
29. Sumino H, Ichikawa S, Kanda T, Nakamura T, Sakamaki T.Reduction of serum uric acid by hormone replacement therapy in postmenopausal women with hyperuricaemia. Lancet 1999;354:650.
30. Conen D, Wietlisbach V, Bovet P, Shamlaye C, Riesen W, Paccaud F, Burnier M. Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country. BMC Public Health 2004;25;4:9.
31. Lee J, Sparrow D, Vokonas PS, Landsberg L, Weiss ST. Uric acid and coronary heart disease risk: evidence for a role of uric acid in the obesity-insulin resistance syndrome. The Normative Aging Study. Am J Epidemiol 1995;142:288-294.
32. Cardona F, Tinahones FJ, Collantes E, Escudero A, García-Fuentes E, Soriguer FJ. Contribution of polymorphisms in the apolipoprotein AI-CIII-AIV cluster to hyperlipidaemia in patients with gout. Ann Rheum Dis 2005;64:85-88.
33. Moriwaki Y, Yamamoto T, Takahashi S, Tsutsumi Z, Higashino K. Apolipoprotein E phenotypes in patients with gout: relation with hypertriglyceridaemia. Ann Rheum Dis 1995;54:351-354.