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Volumn 277, Issue SUPPL. 1, 2009, Pages

What can be learned from open direct comparative trials in multiple sclerosis?

Author keywords

Disability; Glatiramer acetate; Interferon beta; Multiple sclerosis; Observational studies; Relapses

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; GLATIRAMER; INTERFERON BETA SERINE; PLACEBO;

EID: 59349104037     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(09)70008-5     Document Type: Editorial
Times cited : (3)

References (18)
  • 1
    • 0034702233 scopus 로고    scopus 로고
    • A comparison of observational studies and randomized, controlled trials
    • Benson K., and Hartz A.J. A comparison of observational studies and randomized, controlled trials. N Engl J Med 342 (2000) 1878-1886
    • (2000) N Engl J Med , vol.342 , pp. 1878-1886
    • Benson, K.1    Hartz, A.J.2
  • 2
    • 0034702175 scopus 로고    scopus 로고
    • Randomized, controlled trials, observational studies, and the hierarchy of research designs
    • Concato J., Shah N., and Horwitz R.I. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med 342 (2000) 1887-1892
    • (2000) N Engl J Med , vol.342 , pp. 1887-1892
    • Concato, J.1    Shah, N.2    Horwitz, R.I.3
  • 4
    • 0035822324 scopus 로고    scopus 로고
    • Systematic reviews in health care: Assessing the quality of controlled clinical trials
    • Juni P., Altman D.G., and Egger M. Systematic reviews in health care: Assessing the quality of controlled clinical trials. BMJ Clin Res Ed 323 (2001) 42-46
    • (2001) BMJ Clin Res Ed , vol.323 , pp. 42-46
    • Juni, P.1    Altman, D.G.2    Egger, M.3
  • 5
    • 35649026444 scopus 로고    scopus 로고
    • Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles
    • Shrier I., Boivin J.F., Steele R.J., Platt R.W., Furlan A., Kakuma R., et al. Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles. Am J Epidemiol 166 (2007) 1203-1209
    • (2007) Am J Epidemiol , vol.166 , pp. 1203-1209
    • Shrier, I.1    Boivin, J.F.2    Steele, R.J.3    Platt, R.W.4    Furlan, A.5    Kakuma, R.6
  • 6
    • 23844504629 scopus 로고    scopus 로고
    • Observational versus experimental studies: what's the evidence for a hierarchy?
    • Concato J. Observational versus experimental studies: what's the evidence for a hierarchy?. NeuroRx 1 (2004) 341-347
    • (2004) NeuroRx , vol.1 , pp. 341-347
    • Concato, J.1
  • 7
    • 59349115252 scopus 로고    scopus 로고
    • Statistical analysis of clinical endpoints in studies of disease-modifying therapies for multiple sclerosis
    • Cutter G., Sormani M., and Pace A. Statistical analysis of clinical endpoints in studies of disease-modifying therapies for multiple sclerosis. Neurology 70 Suppl 1 (2008) A104
    • (2008) Neurology , vol.70 , Issue.SUPPL. 1
    • Cutter, G.1    Sormani, M.2    Pace, A.3
  • 8
    • 0035211356 scopus 로고    scopus 로고
    • A prospective, open-label treatment trial to compare the effect of IFNbeta-1a (Avonex), IFNbeta-1b (Betaseron), and glatiramer acetate (Copaxone) on the relapse rate in relapsing remitting multiple sclerosis: results after 18 months of therapy
    • Khan O.A., Tselis A.C., Kamholz J.A., Garbern J.Y., Lewis R.A., and Lisak R.P. A prospective, open-label treatment trial to compare the effect of IFNbeta-1a (Avonex), IFNbeta-1b (Betaseron), and glatiramer acetate (Copaxone) on the relapse rate in relapsing remitting multiple sclerosis: results after 18 months of therapy. Mult Scler 7 (2001) 349-353
    • (2001) Mult Scler , vol.7 , pp. 349-353
    • Khan, O.A.1    Tselis, A.C.2    Kamholz, J.A.3    Garbern, J.Y.4    Lewis, R.A.5    Lisak, R.P.6
  • 9
    • 0346964327 scopus 로고    scopus 로고
    • A retrospective, observational study comparing the four available immunomodulatory treatments for relapsing remitting multiple sclerosis
    • Carrá A., Onaha P., Sinay V., Alvarez F., Luetic G., Bettinelli R., et al. A retrospective, observational study comparing the four available immunomodulatory treatments for relapsing remitting multiple sclerosis. Eur J Neurol 10 (2003) 671-676
    • (2003) Eur J Neurol , vol.10 , pp. 671-676
    • Carrá, A.1    Onaha, P.2    Sinay, V.3    Alvarez, F.4    Luetic, G.5    Bettinelli, R.6
  • 10
    • 20044388168 scopus 로고    scopus 로고
    • Twenty-four-month comparison of immunomodulatory treatments a retrospective open label study in 308 RRMS patients treated with beta interferons or glatiramer acetate (Copaxone)
    • Haas J., and Firzlaff M. Twenty-four-month comparison of immunomodulatory treatments a retrospective open label study in 308 RRMS patients treated with beta interferons or glatiramer acetate (Copaxone). Eur J Neurol 12 (2005) 425-431
    • (2005) Eur J Neurol , vol.12 , pp. 425-431
    • Haas, J.1    Firzlaff, M.2
  • 11
    • 33847138511 scopus 로고    scopus 로고
    • Quality Assessment in Multiple Sclerosis Therapy (QUASIMS): a comparison of interferon beta therapies for relapsing remitting multiple sclerosis
    • Limmroth V., Malessa R., Zettl U.K., Koehler J., Japp G., Haller P., et al. Quality Assessment in Multiple Sclerosis Therapy (QUASIMS): a comparison of interferon beta therapies for relapsing remitting multiple sclerosis. J Neurol 254 (2007) 67-77
    • (2007) J Neurol , vol.254 , pp. 67-77
    • Limmroth, V.1    Malessa, R.2    Zettl, U.K.3    Koehler, J.4    Japp, G.5    Haller, P.6
  • 12
    • 43249121843 scopus 로고    scopus 로고
    • The REGARD trial: a randomised assessor-blinded trial comparing interferon beta-la and glatiramer acetate in relapsing remitting multiple sclerosis
    • Mikol D., Barkhof F., Chang P., Coyle P., Jeffery D., Musch B., et al. The REGARD trial: a randomised assessor-blinded trial comparing interferon beta-la and glatiramer acetate in relapsing remitting multiple sclerosis. Mult Scler 13 (2007) S269
    • (2007) Mult Scler , vol.13
    • Mikol, D.1    Barkhof, F.2    Chang, P.3    Coyle, P.4    Jeffery, D.5    Musch, B.6
  • 13
    • 51449084771 scopus 로고    scopus 로고
    • Interferon beta-1b 500mcg, interferon beta-1b 250mcg and glatiramer acetate: primary outcomes of the BEYOND (Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New Dose) study
    • O'Connor P., Arnason B., Comi G., Filippi M., Cook S., Goodin D., et al. Interferon beta-1b 500mcg, interferon beta-1b 250mcg and glatiramer acetate: primary outcomes of the BEYOND (Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New Dose) study. Neurology 70 11; Late Breaking Science Supplement (2008) S004
    • (2008) Neurology , vol.70 , Issue.11 Late Breaking Science SUPPL
    • O'Connor, P.1    Arnason, B.2    Comi, G.3    Filippi, M.4    Cook, S.5    Goodin, D.6
  • 14
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • Kurtzke J.F. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33 (1983) 1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 15
    • 0035091667 scopus 로고    scopus 로고
    • European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis
    • Comi G., Filippi M., Wolinsky J.S., and European/Canadian Glatiramer Acetate Study Group. European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis. Ann Neurol 49 (2001) 290-297
    • (2001) Ann Neurol , vol.49 , pp. 290-297
    • Comi, G.1    Filippi, M.2    Wolinsky, J.S.3
  • 16
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial
    • Johnson K.P., Brooks B.R., Cohen J.A., Ford C.C., Goldstein J., Lisak R.P., et al., The Copolymer 1 Multiple Sclerosis Study Group. Copolymer 1 reduces relapse rate and improves disability in relapsing remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. Neurology 45 (1995) 1268-1276
    • (1995) Neurology , vol.45 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3    Ford, C.C.4    Goldstein, J.5    Lisak, R.P.6
  • 17
    • 0345601517 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet 352 (1998) 1498-1504
    • (1998) Lancet , vol.352 , pp. 1498-1504
  • 18
    • 0029161628 scopus 로고
    • Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial
    • The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. Neurology 45 (1995) 1277-1285
    • (1995) Neurology , vol.45 , pp. 1277-1285


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.