-
1
-
-
37049039050
-
The immune-pineal axis: A shuttle between endocrine and paracrine melatonin sources
-
Markus, R. P., Ferreira, Z. S., Fernandes, P. A. and Cecon, E. (2007) The immune-pineal axis: a shuttle between endocrine and paracrine melatonin sources. Neuroimmunomodulation. 14, 126-133.
-
(2007)
Neuroimmunomodulation
, vol.14
, pp. 126-133
-
-
Markus, R.P.1
Ferreira, Z.S.2
Fernandes, P.A.3
Cecon, E.4
-
2
-
-
33845536018
-
One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
-
Tan, D. X., Manchester, L. C., Terron, M. P., Flores, L. J. and Reiter, R. J. (2007) One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J. Pineal Res. 42, 28-42.
-
(2007)
J. Pineal Res
, vol.42
, pp. 28-42
-
-
Tan, D.X.1
Manchester, L.C.2
Terron, M.P.3
Flores, L.J.4
Reiter, R.J.5
-
3
-
-
37349053724
-
Neurobiological effects of melatonin as related to cancer
-
Hoang, B. X., Shaw, D. G., Pham, P. T. and Levine, S. A. (2007) Neurobiological effects of melatonin as related to cancer. Eur. J. Cancer Prev. 16, 511-516.
-
(2007)
Eur. J. Cancer Prev
, vol.16
, pp. 511-516
-
-
Hoang, B.X.1
Shaw, D.G.2
Pham, P.T.3
Levine, S.A.4
-
4
-
-
33646831160
-
The modulatory role of melatonin on immune responsiveness
-
Carrillo-Vico, A., Reiter, R. J., Lardone, P. J., Herrera, J. L., Fernandez-Montesinos, R., Guerrero, J. M. and Pozo, D. (2006) The modulatory role of melatonin on immune responsiveness. Curr. Opin. Investig. Drugs. 7, 423-431.
-
(2006)
Curr. Opin. Investig. Drugs
, vol.7
, pp. 423-431
-
-
Carrillo-Vico, A.1
Reiter, R.J.2
Lardone, P.J.3
Herrera, J.L.4
Fernandez-Montesinos, R.5
Guerrero, J.M.6
Pozo, D.7
-
5
-
-
39749108884
-
-
Reiter, R. J., Tan, D. X., Manchester, L. C., Pilar, T. M., Flores, L. J. and Koppisepi, S. (2007) Medical implications of melatonin: receptor-mediated and receptor-independent actions. Adv. Med. Sci. 52, 11-28.
-
Reiter, R. J., Tan, D. X., Manchester, L. C., Pilar, T. M., Flores, L. J. and Koppisepi, S. (2007) Medical implications of melatonin: receptor-mediated and receptor-independent actions. Adv. Med. Sci. 52, 11-28.
-
-
-
-
6
-
-
36248957048
-
Melatonin receptors: Role on sleep and circadian rhythm regulation
-
Dubocovich, M. L. (2007) Melatonin receptors: role on sleep and circadian rhythm regulation. Sleep Med. 8 Suppl 3, 34-42.
-
(2007)
Sleep Med
, vol.8
, Issue.SUPPL. 3
, pp. 34-42
-
-
Dubocovich, M.L.1
-
7
-
-
0028104861
-
Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily
-
Becker-Andre, M., Wiesenberg, I., Schaeren-Wiemers, N., Andre, E., Missbach, M., Saurat, J. H. and Carlberg, C. (1994) Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily. J. Biol. Chem. 269, 28531-28534.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 28531-28534
-
-
Becker-Andre, M.1
Wiesenberg, I.2
Schaeren-Wiemers, N.3
Andre, E.4
Missbach, M.5
Saurat, J.H.6
Carlberg, C.7
-
8
-
-
0031570820
-
Melatonin enhances IL-2, IL-6, and IFNgamma production by human circulating CD4+ cells: A possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes
-
Garcia-Maurino, S., Gonzalez-Haba, M. G., Calvo, J. R., Rafii-El-Idrissi, M., Sanchez-Margalet, V., Goberna, R. and Guerrero, J. M. (1997) Melatonin enhances IL-2, IL-6, and IFNgamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes. J. Immunol. 159, 574-81.
-
(1997)
J. Immunol
, vol.159
, pp. 574-581
-
-
Garcia-Maurino, S.1
Gonzalez-Haba, M.G.2
Calvo, J.R.3
Rafii-El-Idrissi, M.4
Sanchez-Margalet, V.5
Goberna, R.6
Guerrero, J.M.7
-
9
-
-
0033536562
-
Melatonin activates Th1 lymphocytes by increasing IL-12 production
-
Garcia-Maurino, S., Pozo, D., Carrillo-Vico, A., Calvo, J. R. and Guerrero, J. M. (1999) Melatonin activates Th1 lymphocytes by increasing IL-12 production. Life Sci. 65, 2143-50.
-
(1999)
Life Sci
, vol.65
, pp. 2143-2150
-
-
Garcia-Maurino, S.1
Pozo, D.2
Carrillo-Vico, A.3
Calvo, J.R.4
Guerrero, J.M.5
-
10
-
-
27644466592
-
A review of the multiple actions of melatonin on the immune system
-
Carrillo-Vico, A., Guerrero, J. M., Lardone, P. J. and Reiter, R. J. (2005) A review of the multiple actions of melatonin on the immune system. Endocrine. 27, 189-200.
-
(2005)
Endocrine
, vol.27
, pp. 189-200
-
-
Carrillo-Vico, A.1
Guerrero, J.M.2
Lardone, P.J.3
Reiter, R.J.4
-
11
-
-
0031047713
-
The diffuse neuroendocrine system and extrapineal melatonin
-
Kvetnoy, I., Sandvik, A. K. and Waldum, H. L. (1997) The diffuse neuroendocrine system and extrapineal melatonin. J. Mol. Endocrinol. 18, 1-3.
-
(1997)
J. Mol. Endocrinol
, vol.18
, pp. 1-3
-
-
Kvetnoy, I.1
Sandvik, A.K.2
Waldum, H.L.3
-
12
-
-
0036264554
-
Gastrointestinal melatonin: Cellular identification and biological role
-
Kvetnoy, I. M., Ingel, I. E., Kvetnaia, T. V., Malinovskaya, N. K., Rapoport, S. I., Raikhlin, N. T., Trofimov, A. V. and Yuzhakov, V. V. (2002) Gastrointestinal melatonin: cellular identification and biological role. Neuro. Endocrinol. Lett. 23, 121-132.
-
(2002)
Neuro. Endocrinol. Lett
, vol.23
, pp. 121-132
-
-
Kvetnoy, I.M.1
Ingel, I.E.2
Kvetnaia, T.V.3
Malinovskaya, N.K.4
Rapoport, S.I.5
Raikhlin, N.T.6
Trofimov, A.V.7
Yuzhakov, V.V.8
-
13
-
-
0032978597
-
Extrapineal melatonin: Location and role within diffuse neuroendocrine system
-
Kvetnoy, I. M. (1999) Extrapineal melatonin: location and role within diffuse neuroendocrine system. Histochem. J. 31, 1-12.
-
(1999)
Histochem. J
, vol.31
, pp. 1-12
-
-
Kvetnoy, I.M.1
-
14
-
-
2442648067
-
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: Possible role as intracrine, autocrine, and/or paracrine substance
-
Carrillo-Vico, A., Calvo, J. R., Abreu, P., Lardone, P. J., Garcia-Maurino, S., Reiter, R. J. and Guerrero, J. M. (2004) Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J. 18, 537-539.
-
(2004)
FASEB J
, vol.18
, pp. 537-539
-
-
Carrillo-Vico, A.1
Calvo, J.R.2
Abreu, P.3
Lardone, P.J.4
Garcia-Maurino, S.5
Reiter, R.J.6
Guerrero, J.M.7
-
15
-
-
14044261745
-
Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system
-
Carrillo-Vico, A., Lardone, P. J., Fernandez-Santos, J. M., Martin-Lacave, I., Calvo, J. R., Karasek, M. and Guerrero, J. M. (2005) Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system. J. Clin. Endocrinol. Metab. 90, 992-1000.
-
(2005)
J. Clin. Endocrinol. Metab
, vol.90
, pp. 992-1000
-
-
Carrillo-Vico, A.1
Lardone, P.J.2
Fernandez-Santos, J.M.3
Martin-Lacave, I.4
Calvo, J.R.5
Karasek, M.6
Guerrero, J.M.7
-
16
-
-
28444485328
-
Melatonin synthesized by Jurkat human leukemic T cell line is implicated in IL-2 production
-
Lardone, P. J., Carrillo-Vico, A., Naranjo, M. C., De, F. B., Vallejo, A., Karasek, M. and Guerrero, J. M. (2006) Melatonin synthesized by Jurkat human leukemic T cell line is implicated in IL-2 production. J. Cell Physiol. 206, 273-279.
-
(2006)
J. Cell Physiol
, vol.206
, pp. 273-279
-
-
Lardone, P.J.1
Carrillo-Vico, A.2
Naranjo, M.C.3
De, F.B.4
Vallejo, A.5
Karasek, M.6
Guerrero, J.M.7
-
17
-
-
0032444559
-
Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells
-
Garcia-Maurino, S., Gonzalez-Haba, M. G., Calvo, J. R., Goberna, R. and Guerrero, J. M. (1998) Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells. J. Neuroimmunol. 92, 76-84.
-
(1998)
J. Neuroimmunol
, vol.92
, pp. 76-84
-
-
Garcia-Maurino, S.1
Gonzalez-Haba, M.G.2
Calvo, J.R.3
Goberna, R.4
Guerrero, J.M.5
-
18
-
-
0033809810
-
Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines
-
Garcia-Maurino, S., Pozo, D., Calvo, J. R. and Guerrero, J. M. (2000) Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines. J. Pineal Res. 29, 129-37.
-
(2000)
J. Pineal Res
, vol.29
, pp. 129-137
-
-
Garcia-Maurino, S.1
Pozo, D.2
Calvo, J.R.3
Guerrero, J.M.4
-
19
-
-
0037389137
-
Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor
-
Carrillo-Vico, A., Garcia-Maurino, S., Calvo, J. R. and Guerrero, J. M. (2003) Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor. FASEB J. 17, 755-757.
-
(2003)
FASEB J
, vol.17
, pp. 755-757
-
-
Carrillo-Vico, A.1
Garcia-Maurino, S.2
Calvo, J.R.3
Guerrero, J.M.4
-
20
-
-
0014385564
-
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
-
Boyum, A. (1968) Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab Invest Suppl. 97, 77-89.
-
(1968)
Scand. J. Clin. Lab Invest Suppl
, vol.97
, pp. 77-89
-
-
Boyum, A.1
-
21
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
22
-
-
0020061358
-
Prostaglandin E inhibits the production of human interleukin 2
-
Rappaport, R. S. and Dodge, G. R. (1982) Prostaglandin E inhibits the production of human interleukin 2. J. Exp. Med. 155, 943-948.
-
(1982)
J. Exp. Med
, vol.155
, pp. 943-948
-
-
Rappaport, R.S.1
Dodge, G.R.2
-
23
-
-
0031572436
-
Signal transduction for melatonin in human lymphocytes: Involvement of a pertussis toxin-sensitive G protein
-
Garcia-Perganeda, A., Pozo, D., Guerrero, J. M. and Calvo, J. R. (1997) Signal transduction for melatonin in human lymphocytes: involvement of a pertussis toxin-sensitive G protein. J. Immunol. 159, 3774-3781.
-
(1997)
J. Immunol
, vol.159
, pp. 3774-3781
-
-
Garcia-Perganeda, A.1
Pozo, D.2
Guerrero, J.M.3
Calvo, J.R.4
-
24
-
-
0032161469
-
Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
-
Dubocovich, M. L., Yun, K., Al-Ghoul, W. M., Benloucif, S. and Masana, M. I. (1998) Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J. 12, 1211-1220.
-
(1998)
FASEB J
, vol.12
, pp. 1211-1220
-
-
Dubocovich, M.L.1
Yun, K.2
Al-Ghoul, W.M.3
Benloucif, S.4
Masana, M.I.5
-
25
-
-
0029115639
-
Molecular characterization of a second melatonin receptor expressed in human retina and brain: The Mel1b melatonin receptor
-
Reppert, S. M., Godson, C., Mahle, C. D., Weaver, D. R., Slaugenhaupt, S. A. and Gusella, J. F. (1995) Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor. Proc. Natl. Acad. Sci. U. S. A. 92, 8734-8738.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A
, vol.92
, pp. 8734-8738
-
-
Reppert, S.M.1
Godson, C.2
Mahle, C.D.3
Weaver, D.R.4
Slaugenhaupt, S.A.5
Gusella, J.F.6
-
26
-
-
0017199306
-
Selective in vitro growth of T lymphocytes from normal human bone marrows
-
Morgan, D. A., Ruscetti, F. W. and Gallo, R. (1976) Selective in vitro growth of T lymphocytes from normal human bone marrows. Science. 193, 1007-1008.
-
(1976)
Science
, vol.193
, pp. 1007-1008
-
-
Morgan, D.A.1
Ruscetti, F.W.2
Gallo, R.3
-
27
-
-
0030067103
-
Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression
-
Akbar, A. N., Borthwick, N. J., Wickremasinghe, R. G., Panayoitidis, P., Pilling, D., Bofill, M., Krajewski, S., Reed, J. C. and Salmon, M. (1996) Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression. Eur. J. Immunol. 26, 294-299.
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 294-299
-
-
Akbar, A.N.1
Borthwick, N.J.2
Wickremasinghe, R.G.3
Panayoitidis, P.4
Pilling, D.5
Bofill, M.6
Krajewski, S.7
Reed, J.C.8
Salmon, M.9
-
28
-
-
38449083826
-
IL-2 signaling and CD4+ CD25+ Foxp3+ regulatory T cells
-
Turka, L. A. and Walsh, P. T. (2008) IL-2 signaling and CD4+ CD25+ Foxp3+ regulatory T cells. Front Biosci. 13, 1440-1446.
-
(2008)
Front Biosci
, vol.13
, pp. 1440-1446
-
-
Turka, L.A.1
Walsh, P.T.2
-
29
-
-
43249128068
-
Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system
-
Anderton, S. M. and Liblau, R. S. (2008) Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system. Curr. Opin. Neurol. 21, 248-254.
-
(2008)
Curr. Opin. Neurol
, vol.21
, pp. 248-254
-
-
Anderton, S.M.1
Liblau, R.S.2
-
30
-
-
22544436066
-
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells
-
Baratelli, F., Lin, Y., Zhu, L., Yang, S. C., Heuze-Vourc'h, N., Zeng, G., Reckamp, K., Dohadwala, M., Sharma, S. and Dubinett, S. M. (2005) Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J. Immunol. 175, 1483-1490.
-
(2005)
J. Immunol
, vol.175
, pp. 1483-1490
-
-
Baratelli, F.1
Lin, Y.2
Zhu, L.3
Yang, S.C.4
Heuze-Vourc'h, N.5
Zeng, G.6
Reckamp, K.7
Dohadwala, M.8
Sharma, S.9
Dubinett, S.M.10
-
31
-
-
33745311263
-
FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism
-
Mahic, M., Yaqub, S., Johansson, C. C., Tasken, K. and Aandahl, E. M. (2006) FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism. J. Immunol. 177, 246-254.
-
(2006)
J. Immunol
, vol.177
, pp. 246-254
-
-
Mahic, M.1
Yaqub, S.2
Johansson, C.C.3
Tasken, K.4
Aandahl, E.M.5
-
32
-
-
85120518431
-
-
Narumiya, S. (1994) Prostanoid receptors. Structure, function, and distribution. Ann. N. Y. Acad. Sci. 744, 126-138.
-
Narumiya, S. (1994) Prostanoid receptors. Structure, function, and distribution. Ann. N. Y. Acad. Sci. 744, 126-138.
-
-
-
-
33
-
-
0033670391
-
Involvement of nuclear receptors in the enhanced IL-2 production by melatonin in Jurkat cells
-
Guerrero, J. M., Pozo, D., Garcia-Maurino, S., Osuna, C., Molinero, P. and Calvo, J. R. (2000) Involvement of nuclear receptors in the enhanced IL-2 production by melatonin in Jurkat cells. Ann. N. Y. Acad. Sci. 917, 397-403.
-
(2000)
Ann. N. Y. Acad. Sci
, vol.917
, pp. 397-403
-
-
Guerrero, J.M.1
Pozo, D.2
Garcia-Maurino, S.3
Osuna, C.4
Molinero, P.5
Calvo, J.R.6
-
34
-
-
0025167233
-
Delineation of the mechanism of inhibition of human T cell activation by PGE2
-
Minakuchi, R., Wacholtz, M. C., Davis, L. S. and Lipsky, P. E. (1990) Delineation of the mechanism of inhibition of human T cell activation by PGE2. J. Immunol. 145, 2616-2625.
-
(1990)
J. Immunol
, vol.145
, pp. 2616-2625
-
-
Minakuchi, R.1
Wacholtz, M.C.2
Davis, L.S.3
Lipsky, P.E.4
-
35
-
-
0026773781
-
New insights into activation of the steroid hormone receptor superfamily
-
Power, R. F., Conneely, O. M. and O'Malley, B. W. (1992) New insights into activation of the steroid hormone receptor superfamily. Trends Pharmacol. Sci. 13, 318-323.
-
(1992)
Trends Pharmacol. Sci
, vol.13
, pp. 318-323
-
-
Power, R.F.1
Conneely, O.M.2
O'Malley, B.W.3
-
36
-
-
0035818690
-
-
Masana, M. I. and Dubocovich, M. L. (2001) Melatonin receptor signaling: finding the path through the dark. Sci. STKE. 2001, E39-
-
Masana, M. I. and Dubocovich, M. L. (2001) Melatonin receptor signaling: finding the path through the dark. Sci. STKE. 2001, E39-
-
-
-
-
37
-
-
0037418623
-
Melatonin receptors and their regulation: Biochemical and structural mechanisms
-
Witt-Enderby, P. A., Bennett, J., Jarzynka, M. J., Firestine, S. and Melan, M. A. (2003) Melatonin receptors and their regulation: biochemical and structural mechanisms. Life Sci. 72, 2183-2198.
-
(2003)
Life Sci
, vol.72
, pp. 2183-2198
-
-
Witt-Enderby, P.A.1
Bennett, J.2
Jarzynka, M.J.3
Firestine, S.4
Melan, M.A.5
-
38
-
-
0034651698
-
Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV
-
Kane, C. D. and Means, A. R. (2000) Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV. EMBO J. 19, 691-701.
-
(2000)
EMBO J
, vol.19
, pp. 691-701
-
-
Kane, C.D.1
Means, A.R.2
-
39
-
-
42649100262
-
Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors
-
Audinot, V., Bonnaud, A., Grandcolas, L., Rodriguez, M., Nagel, N., Galizzi, J. P., Balik, A., Messager, S., Hazlerigg, D. G., Barrett, P., Delagrange, P. and Boutin, J. A. (2008) Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors. Biochem. Pharmacol. 75, 2007-2019.
-
(2008)
Biochem. Pharmacol
, vol.75
, pp. 2007-2019
-
-
Audinot, V.1
Bonnaud, A.2
Grandcolas, L.3
Rodriguez, M.4
Nagel, N.5
Galizzi, J.P.6
Balik, A.7
Messager, S.8
Hazlerigg, D.G.9
Barrett, P.10
Delagrange, P.11
Boutin, J.A.12
-
40
-
-
2942580561
-
Molecular pharmacology, regulation and function of mammalian melatonin receptors
-
Dubocovich, M. L., Rivera-Bermudez, M. A., Gerdin, M. J. and Masana, M. I. (2003) Molecular pharmacology, regulation and function of mammalian melatonin receptors. Front Biosci. 8, d1093-d1108.
-
(2003)
Front Biosci
, vol.8
-
-
Dubocovich, M.L.1
Rivera-Bermudez, M.A.2
Gerdin, M.J.3
Masana, M.I.4
-
41
-
-
0035946833
-
Transcriptional repression of RORalpha activity in human breast cancer cells by melatonin
-
Dai, J., Ram, P. T., Yuan, L., Spriggs, L. L. and Hill, S. M. (2001) Transcriptional repression of RORalpha activity in human breast cancer cells by melatonin. Mol. Cell Endocrinol. 176, 111-120.
-
(2001)
Mol. Cell Endocrinol
, vol.176
, pp. 111-120
-
-
Dai, J.1
Ram, P.T.2
Yuan, L.3
Spriggs, L.L.4
Hill, S.M.5
|