Zinc supplementation does not alter plasma homocysteine, vitamin B12 and red blood cell folate concentrations in French elderly subjects

Journal of Trace Elements in Medicine and Biology

Volumn 23, Issue 1, 2009, Pages 15-20

  Ducros, Véronique ^a,b   Andriollo Sanchez, Maud ^b,c   Arnaud, Josiane ^a,b   Meunier, Nathalie ^d   Laporte, François ^a,b,c   Hininger Favier, Isabelle ^b,c   Coudray, Charles ^d   Ferry, Monique ^e   Roussel, Anne Marie ^b,c  

^a GRENOBLE UNIVERSITY HOSPITAL   (France)

^b INSERM   (France)

^c UNIV GRENOBLE ALPES   (France)

^d CEMAGREF   (France)

^e CENTRE HOSPITALIER DE VALENCE   (France)

Author keywords

Ageing; Folates; Homocysteine; Vitamin B12; Zinc supplementation

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; GLUCONATE ZINC; HOMOCYSTEINE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ERYTHROCYTE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SUPPLEMENTATION;

EID: 59349099323     PISSN: 0946672X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtemb.2008.08.003     Document Type: Article

References (27)

1. Gonzalez S., Huerta J.M., Fernandez S., Patterson A.M., and Lasheras C. Homocysteine increases the risk of mortality in elderly individuals. Br J Nutr 97 (2007) 1138-1143
2. Haan M.N., Miller J.W., Aiello A.E., Whitmer R.A., Jagust W.J., Mungas D.M., et al. Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging. Am J Clin Nutr 85 (2007) 511-517
3. Hotz C., Peerson J.M., and Brown K.H. Suggested lower cutoffs of serum zinc concentrations for assessing zinc status: reanalysis of the second National Health and Nutrition Examination Survey data (1976-1980). Am J Clin Nutr 78 (2003) 756-764
4. Mariani E., Cornacchiola V., Polidori M.C., Mangialasche F., Malavolta M., Cecchetti R., et al. Antioxidant enzyme activities in healthy old subjects: influence of age, gender and zinc status. Biogerontology 7 (2006) 391-398
5. Coudray C., O'Connor J.M., Maiani G., Cashman K.D., Simpson E.E.A., Secker D.L., et al. Introduction to the ZENITH study and summary of baseline results. Eur J Clin Nutr 59 (2005) S5-7
6. Polito A., Meunier N., Andriollo-Sanchez M., Catasta G., Azzini E., Simpson E.E.A., et al. Screening and recruitment procedure of late-middle aged and older subjects: the ZENITH study. Eur J Clin Nutr 59 (2005) S8-12
7. Polito A., Intorre F., Andriollo-Sanchez M., Azzini E., Raguzzini A., Meunier N., et al. Estimation of intake and status of vitamin A, vitamin E and folate in older European adults: the ZENITH. Eur J Clin Nutr 59 (2005) S42-S47
8. Halsted C. The intestinal absorption of dietary folates in health and diseases. J Am Coll Nutr 8 (1989) 650-658
9. Milne D.B., Canfield W.K., Mahalko J.R., and Sandstead H.H. Effect of oral folic acid supplements on zinc, copper and iron absorption and excretion. Am J Clin Nutr 39 (1984) 535-539
10. Maret W., and Sandstead H.H. Zinc requirements and the risks and benefits of zinc supplementation. J Trace Elem Med Biol 20 (2006) 3-18
11. Prasad A.S. Essentiality and toxicity of zinc. Scand J Work Environ Health 19 Suppl. 1 (1993) 134-136
12. Arnaud J., Bellanger J., Bienvenu F., Chappuis P., and Favier A. Recommended method for assaying serum zinc with flame atomic absorption. Ann Biol Clin 44 (1986) 77-87
13. Andriollo-Sanchez M., Hininger-Favier I., Meunier N., Toti E., Zaccaria M., Brandollini-Bunlon M., et al. Zinc intake and status in middle-aged and older European subjects: the ZENITH study. Eur J Clin Nutr 59 (2005) S37-41
14. Snow C.F. Laboratory diagnosis of vitamin B12 and folate deficiency. A guide for the primary care physician. Arch Intern Med 159 (1999) 1289-1298
15. Iyengar G.V. Reevaluation of the trace element content in reference man. Radiat Phys Chem 51 (1998) 545-560
16. Arnaud J., Chappuis P., Jaudon M.C., and Bellanger J. Nutritional biological markers of deficiencies of zinc, copper and selenium. Ann Biol Clin 51 (1993) 589-604
17. Delves H.T. Assessment of trace element status. Clin Endocrinol Metabol 3 (1985) 725-760
18. Favier M., Faure P., Roussel A.M., Coudray C., Blache D., and Favier A. Zinc deficiency and dietary folate metabolism in pregnant rats. J Trace Elem Electrolytes Health Dis 7 (1993) 19-24
19. Arnaud J., Favier A., Herrmann M.A., and Pilorget J.J. Effect of folic and folinic acids on zinc intestinal absorption. Ann Nutr Metab 36 (1992) 157-161
20. Keating J.N., Wada L., Stokstad E.L.R., and King J.C. Folic acid: effect on zinc absorption in humans and in the rat. Am J Clin Nutr 46 (1987) 835-839
21. Wang R., Zhu X., Guo F., Zhang W., and Jia Z. Influence of different dietary levels of zinc on performance, vitamin B12, and blood parameters in lambs. Int J Vitam Nutr Res 76 (2006) 353-358
22. Tamura T., Kaiser L.L., Watson J.E., Halsted C.H., Hurley L.S., and Stokstad E.L. Increased methionine synthase activity in zinc-deficient rat liver. Arch Biochem Biophys 256 (1987) 311-316
23. Hong K.H., Keen C.L., Mizuno Y., Johnston K.E., and Tamura T. Effect of dietary zinc deficiency on homocysteine and folate metabolism in rats. J Nutr Biochem 11 (2000) 165-169
24. Intorre F., Polito A., Andriollo-Sanchez M., Azzini E., Raguzzini A., Toti E., et al. Effect of zinc supplementation on vitamin status of middle-aged and older European adults: the ZENITH study. Eur J Clin Nutr (2007) [advance online publication]
25. King J.C. Assessment of zinc status. J Nutr 120 (1990) 1474-1479
26. Simpson E.E.A., O'Connor, Livingstone M.B.E., Rae G., Stewart-Knox B.J., Andriollo-Sanchez M., et al. Health and lifestyle characteristics of older European adults: the ZENITH study. Eur J Clin Nutr 59 (2005) S13-21
27. Refsum H., Smith A.D., Ueland P.M., Nexo E., Clarke R., McPartlin J., et al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 50 (2004) 3-32