Clinical and treatment comparisons between adults with early- and late-onset obsessive-compulsive disorder

Behaviour Research and Therapy

Volumn 47, Issue 2, 2009, Pages 99-104

  Lomax, Claire L ^a   Oldfield, Victoria B ^a   Salkovskis, Paul M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Age of onset; Cognitive behavioural therapy; Early onset OCD; Late onset OCD; Obsessive compulsive disorder (OCD)

Indexed keywords

ADOLESCENT; ADULT; AGE OF ONSET; CHILD; COGNITIVE THERAPY; FEMALE; HUMANS; MALE; OBSESSIVE-COMPULSIVE DISORDER; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; COGNITIVE THERAPY; FEMALE; HUMAN; MALE; OBSESSIVE-COMPULSIVE DISORDER; ONSET AGE; PROCEDURES; PROGNOSIS; PSYCHOLOGICAL RATING SCALE; RETROSPECTIVE STUDY; TREATMENT OUTCOME; YOUNG ADULT;

EID: 59349084907     PISSN: 00057967     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brat.2008.10.015     Document Type: Article

References (45)

1. Ackerman D.L., Greenland S., and Bystritsky A. Clinical characteristics of response to fluoxetine treatment of obsessive-compulsive disorder. Journal of Clinical Psychopharmacology 18 3 (1998) 185-192
2. Ackerman D.L., Greenland S., Bystritsky A., Morgenstern H., and Katz R.J. Predictors of treatment response in obsessive-compulsive disorder: multivariate analyses from a multicenter trial of clomipramine. Journal of Clinical Psychopharmacology 14 4 (1994) 247-254
3. Alonso P., Menchon J.M., Pifarre J., Mataix-Cols D., Torres L., Salgado P., et al. Long-term follow-up and predictors of clinical outcome in obsessive-compulsive patients treated with serotonin reuptake inhibitors and behavioural therapy. Journal of Clinical Psychiatry 62 7 (2001) 535-540
4. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (2000), American Psychiatric Association, Washington, DC
5. Aylward E.H., Harris G.I., Hoehn-Saric R., Barta P.E., Machlin S.R., and Pearlson G.D. Normal caudate nucleus in obsessive-compulsive disorder assessed by quantitative neuroimaging. Archives of General Psychiatry 53 (1996) 577-584
6. Beck A.T., Epstein N., Brown G., and Steer R.A. An inventory for measuring clinical anxiety: psychometric properties. Journal of Consulting and Clinical Psychology 56 (1988) 893-897
7. Beck A.T., and Steer R.A. Manual for the Beck Depression Inventory (1987), Psychological Corporation, San Antonio, TX
8. Brewin C.R., Andrews B., and Gotlib I.H. Psychopathology and early experience: a reappraisal of retrospective reports. Psychological Bulletin 113 1 (1993) 82-98
9. Chabane N., Delorme R., Millet B., Mouren M.C., Leboyer M., and Pauls D. Early-onset obsessive-compulsive disorder: a subgroup with a specific clinical and familial pattern?. Journal of Child Psychology & Psychiatry & Allied Disciplines 46 8 (2005) 881-887
10. Delorme R., Golmard J., Chabane N., Millet B., Krebs M., Mouren-Simeoni M., et al. Admixture analysis of age at onset in obsessive-compulsive disorder. Psychological Medicine 35 2 (2005) 237-243
11. Diniz J.B., Rosario-Campos M.C., Shavitt R.G., Curi M., Hounie A.G., Brotto S.A., et al. Impact of age at onset and duration of illness on the expression of comorbidities in obsessive-compulsive disorder. The Journal of Clinical Psychiatry 65 1 (2004) 22-27
12. First M.B., Spitzer R.L., Gibbon M., and Williams J.B.W. Structured Clinical Interview for DSM-IV Axis 1 Disorders (SCID-IP, Version 2.0). Patient ed. (1996), Biometrics Research Department, New York State Psychiatric Institute, New York
13. Foa E.B., Kozak M.J., Salkovskis P.M., Coles M.E., and Amir N. The validation of a new obsessive-compulsive disorder scale: the Obsessive-Compulsive Inventory. Psychological Assessment 10 3 (1998) 206-214
14. Fontenelle L., Mendlowicz M.V., Marques C., and Versiani M. Early- and late-onset obsessive-compulsive disorder in adult patients: an exploratory clinical and therapeutic study. Journal of Psychiatric Research 37 2 (2003) 127-133
15. Fyer A.J., Lipsitz J.D., Mannuzza S., Aronowitz B., and Chapman T.F. A direct interview family study of obsessive-compulsive disorder. Psychological Medicine 35 11 (2005) 1611-1621
16. Garvey M.A., Giedd J., and Swedo S.E. PANDAS: the search for environmental triggers of pediatric neuropsychiatric disorders. Lessons from rheumatic fever. Journal of Child Neurology 13 (1998) 413-423
17. Geller D.A., Wagner K.D., Emslie G., Murphy T., Carpenter D.J., Wetherhold E., et al. Paroxetine treatment in children and adolescents with obsessive-compulsive disorder: a randomized, multicenter, double-blind, placebo-controlled trial. Journal of the American Academy of Child & Adolescent Psychiatry 43 11 (2004) 1387-1396
18. Gilbert A.R., Moore G.J., Keshavan M.S., Paulson L.A., Narula V., Mac Master F.P., et al. Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine. Archives of General Psychiatry 57 (2000) 449-456
19. Goldstein R., Wickramaratne P., Horwath E., and Weissman M. Familial aggregation and phenomenology of "early"-onset (at or before age 20 years) panic disorder. Archives of General Psychiatry 54 3 (1997) 271-278
20. Gollan J., Raffety B., Gortner E., and Dobson K. Course profiles of early- and adult-onset depression. Journal of Affective Disorders 86 1 (2005) 81-86
21. Goodman W.K., Price L.H., Rasmussen S.A., Mazure C., Delgado P., Heninger G.R., et al. The Yale-Brown Obsessive Compulsive Scale. II. Validity. Archives of General Psychiatry 46 (1989) 1012-1016
22. Hwang S.H., Kwon J.S., Shin Y.W., Lee K.J., Kim Y.Y., and Kim M.S. Neuropsychological profiles of patients with obsessive-compulsive disorder: early onset versus late onset. Journal of the International Neuropsychological Society 13 1 (2007) 30-37
23. Jaisoorya T.S., Reddy Y.C., Janardhan Y., and Srinath S. Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? Findings from an Indian study. European Child & Adolescent Psychiatry 12 6 (2003) 290-297
24. Jänsch G., Zaudiga M., Röper G., Haukea W., Piesbergen C., and Butollo W. The early onset of obsessive-compulsive disorder and its impact on symptomatology and severity. Verhaltenstherapie 17 (2007) 37-43
25. Jenike M.A., Baer L., Minichiello W.E., Rauch S.L., and Buttolph M.L. Placebo-controlled trial of fluoxetine and phenelzine for obsessive-compulsive disorder. American Journal of Psychiatry 154 9 (1997) 1261-1264
26. Kim B.N. Child and adolescent onset obsessive-compulsive disorder. Korean Journal of Psychopharmacology 14 (2003) 119-128
27. Langner, J., Laws, M., Röper, G., Zaudig, M., Hauke, W., & Piesbergen, C. (in press). Predicting therapy outcome in patients with early and late obsessive-compulsive disorder (EOCD and LOCD).
28. Miguel E.C., Rauch S.L., and Jenike M.A. Obsessive-compulsive disorder. Psychiatric Clinics of North America 20 4 (1997) 863-883
29. Miguel E.C., Rosario-Campos M.S., Shavitt R.G., Hounie A.G., and Mercadante M.G. The tic related obsessive-compulsive disorder phenotype and treatment implications. Advances in Neurology 83 (2001) 43-55
30. Millet B., Kochman F., Gallarda T., Krebs M., Demonfaucon F., Barrot I., et al. Phenomenological and comorbid features associated in obsessive-compulsive disorder: influence of age of onset. Journal of Affective Disorders 79 1-3 (2004) 241-246
31. Nestadt G., Samuels J., Riddle M.A., Bienvenu O.J., Liang K.Y., La Buda M., et al. A family study of obsessive-compulsive disorder. Archives of General Psychology 57 (2000) 358-363
32. Pauls D.L., Alsobrook J.P., Godman W., Rasmussen L., and Leckman J.F. A family-study of obsessive-compulsive disorder. American Journal of Psychiatry 152 (1995) 76-84
33. Ravizza L., Barzega G., Bellino S., Bogetto F., and Maina G. Predictors of drug treatment response in obsessive-compulsive disorder. Journal of Clinical Psychiatry 56 8 (1995) 368-373
34. Riddle M. Obsessive-compulsive disorder in children and adolescents. British Journal of Psychiatry 173 Suppl. 35 (1998) 91-96
35. Rosario-Campos M., Leckman J., Mercadante M.T., Shavitt R., da Silva Prado H., Sada P., et al. Adults with early-onset obsessive-compulsive disorder. American Journal of Psychiatry 158 11 (2001) 1899-1903
36. Roth R.M., Milovan D., Baribeau J., and O'Connor K. Neuropsychological functioning in early- and late-onset obsessive-compulsive disorder. Journal of Neuropsychiatry and Clinical Neuroscience 17 (2005) 208-213
37. Salkovskis P.M., Wroe A.L., Gledhill A., Morrison N., Forrester E., Richards C., et al. Responsibility attitudes and interpretations are characteristic of obsessive compulsive disorder. Behaviour Research and Therapy 38 (2000) 347-372
38. Saxena S., Brody A.L., Maidment K.M., Dunkin J., Colgan M., Alborzian S., et al. Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive-compulsive disorder. Neuropsychopharmacology 21 6 (1999) 683-693
39. Segal D.L., Hersen M., and Van Hasselt V.B. Reliability of the Structured Clinical Interview for DSM-III-R: an evaluative review. Comprehensive Psychiatry 35 (1994) 316-327
40. Shavitt R.G., Belotto C., Curi M., Hounie A.G., Rosario-Campos M.C., Diniz J.B., et al. Clinical features associated with treatment response in obsessive-compulsive disorder. Comprehensive Psychiatry 47 4 (2006) 276-281
41. Sobin C., Blundell M.L., and Karayiorgou M. Phenotypic differences in early- and late-onset obsessive-compulsive disorder. Comprehensive Psychiatry 41 5 (2000) 373-379
42. Statistical package for the social sciences for Windows (SPSS) version 12 (2004), SPSS Inc, Chicago, IL
43. Swedo S.E., Leonard H.L., Garvey M., Mittleman B., Allen A.J., Perlmutter S., et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases. American Journal of Psychiatry 155 2 (1998) 264-271
44. Tukel R., Ertekin E., Batmaz S., Alyanak F., Sozen A., Aslantas B., et al. Influence of age of onset on clinical features in obsessive-compulsive disorder. Depression and Anxiety 21 3 (2005) 112-117
45. Uguz F., Askin R., Cilli A.S., and Besiroglu L. Comparison of treatment responses and clinical characteristics of early-onset and late-onset obsessive-compulsive disorder. International Journal of Psychiatry in Clinical Practice 10 4 (2006) 291-296