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Volumn 22, Issue 2, 2009, Pages 182-190

N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas

Author keywords

Cholangiocarcinoma; E cadherin; N cadherin; Tissue microarrays

Indexed keywords

ANTIBODY; CYTOKERATIN 19; CYTOKERATIN 20; CYTOKERATIN 7; HEPATOCYTE PARAFFIN 1 PROTEIN; NERVE CELL ADHESION MOLECULE; PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 59149105595     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.123     Document Type: Article
Times cited : (46)

References (36)
  • 1
    • 34248995330 scopus 로고    scopus 로고
    • Biliary intraepithelial neoplasia: An international interobserver agreement study and proposal for diagnostic criteria
    • Zen Y, Adsay NV, Bardadin K, et al. Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria. Mod Pathol 2007;20:701-709.
    • (2007) Mod Pathol , vol.20 , pp. 701-709
    • Zen, Y.1    Adsay, N.V.2    Bardadin, K.3
  • 2
    • 0017364058 scopus 로고
    • Clinical aspects of intrahepatic bile duct carcinoma including hilar carcinoma: A study of 57 autopsy-proven cases
    • Okuda K, Kubo Y, Okazaki N, et al. Clinical aspects of intrahepatic bile duct carcinoma including hilar carcinoma: a study of 57 autopsy-proven cases. Cancer 1977;39:232-246.
    • (1977) Cancer , vol.39 , pp. 232-246
    • Okuda, K.1    Kubo, Y.2    Okazaki, N.3
  • 3
    • 33745275877 scopus 로고    scopus 로고
    • Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States
    • Welzel TM, McGlynn KA, Hsing AW, et al. Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States. J Natl Cancer Inst 2006;98:873-875.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 873-875
    • Welzel, T.M.1    McGlynn, K.A.2    Hsing, A.W.3
  • 4
    • 0034081962 scopus 로고    scopus 로고
    • Cytokeratin 7 and 20 expression in cholangiocarcinomas varies along the biliary tract but still differs from that in colorectal carcinoma metastasis
    • Rullier A, LeBail B, Fawaz R, et al. Cytokeratin 7 and 20 expression in cholangiocarcinomas varies along the biliary tract but still differs from that in colorectal carcinoma metastasis. Am J Surg Pathol 2000;24:870-876.
    • (2000) Am J Surg Pathol , vol.24 , pp. 870-876
    • Rullier, A.1    LeBail, B.2    Fawaz, R.3
  • 5
    • 0036916550 scopus 로고    scopus 로고
    • Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma
    • Lau SK, Prakash S, Geller SA, et al. Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma. Hum Pathol 2002;33:1175-1181.
    • (2002) Hum Pathol , vol.33 , pp. 1175-1181
    • Lau, S.K.1    Prakash, S.2    Geller, S.A.3
  • 6
    • 0025894092 scopus 로고
    • Cadherins: Cell adhesion receptors as a morphogenetic regulator
    • Takeichi M. Cadherins: cell adhesion receptors as a morphogenetic regulator. Science 1991;251:1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 7
    • 0029057762 scopus 로고
    • Expression of gap junction protein connexin 32 and E-cadherin in human hepatocellular carcinoma
    • Yamaoka K, Nouchi T, Tazawa J, et al. Expression of gap junction protein connexin 32 and E-cadherin in human hepatocellular carcinoma. J Hepatol 1995;22:536-539.
    • (1995) J Hepatol , vol.22 , pp. 536-539
    • Yamaoka, K.1    Nouchi, T.2    Tazawa, J.3
  • 8
    • 0029976344 scopus 로고    scopus 로고
    • Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver
    • Kozyraki R, Scoazec JY, Flejou JF, et al. Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver. Gastroenterology 1996;110:1137-1149.
    • (1996) Gastroenterology , vol.110 , pp. 1137-1149
    • Kozyraki, R.1    Scoazec, J.Y.2    Flejou, J.F.3
  • 9
    • 0029977262 scopus 로고    scopus 로고
    • Expression of epithelial cadherin and alpha- and beta-catenins in nontumoral livers and hepatocellular carcinomas
    • Ihara A, Koizumi H, Hashizume R, et al. Expression of epithelial cadherin and alpha- and beta-catenins in nontumoral livers and hepatocellular carcinomas. Hepatology 1996;2:1441-1447.
    • (1996) Hepatology , vol.2 , pp. 1441-1447
    • Ihara, A.1    Koizumi, H.2    Hashizume, R.3
  • 10
    • 0034067979 scopus 로고    scopus 로고
    • Immunoreactive E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin proteins in hepatocellular carcinoma: Relationships with tumor grade, clinicopathologic parameters, and patients' survival
    • Endo K, Ueda T, Ueyama J, et al. Immunoreactive E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin proteins in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, and patients' survival. Hum Pathol 2000;31:558-565.
    • (2000) Hum Pathol , vol.31 , pp. 558-565
    • Endo, K.1    Ueda, T.2    Ueyama, J.3
  • 11
    • 0034905286 scopus 로고    scopus 로고
    • Frequent downregulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas
    • Matsumura T, Makino R, Mitamura K. Frequent downregulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas. Clin Cancer Res 2001;7:594-599.
    • (2001) Clin Cancer Res , vol.7 , pp. 594-599
    • Matsumura, T.1    Makino, R.2    Mitamura, K.3
  • 12
    • 0036725378 scopus 로고    scopus 로고
    • Altered expression of E-cadherin in hepatocellular carcinoma: Correlations with genetic alterations, beta-catenin expression, and clinical features
    • Wei Y, Van Nhieu JT, Prigent S, et al. Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, beta-catenin expression, and clinical features. Hepatology 2002;36:692-701.
    • (2002) Hepatology , vol.36 , pp. 692-701
    • Wei, Y.1    Van Nhieu, J.T.2    Prigent, S.3
  • 13
    • 0031948695 scopus 로고    scopus 로고
    • Expression of E-cadherin, α-catenin, β-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinomas: An immunohistochemical study
    • Ashida K, Terada T, Kitamura Y, et al. Expression of E-cadherin, α-catenin, β-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinomas: an immunohistochemical study. Hepatology 1998;27:974-982.
    • (1998) Hepatology , vol.27 , pp. 974-982
    • Ashida, K.1    Terada, T.2    Kitamura, Y.3
  • 14
    • 0035023285 scopus 로고    scopus 로고
    • Recommandations pour la cryoconservation de cellules et tissus tumoraux dans le but de réaliser des analyses moléculaires.
    • ANAES
    • ANAES. Recommandations pour la cryoconservation de cellules et tissus tumoraux dans le but de réaliser des analyses moléculaires. Ann Pathol 2001;21:184-201.
    • (2001) Ann Pathol , vol.21 , pp. 184-201
  • 16
    • 0028896159 scopus 로고
    • Bcl2 and p53 oncoprotein expression during colorectal tumorogenesis
    • Sinicrope FA, Ruan SB, Cleary KR, et al. Bcl2 and p53 oncoprotein expression during colorectal tumorogenesis. Cancer Res 1995;55:237-241.
    • (1995) Cancer Res , vol.55 , pp. 237-241
    • Sinicrope, F.A.1    Ruan, S.B.2    Cleary, K.R.3
  • 17
    • 26044458615 scopus 로고    scopus 로고
    • Up-regulated expression of ADAM17 in human colon carcinomas: Co-expression with EGFR in neoplastic and endothelial cells
    • Blanchot-Jossic F, Jarry A, Masson D, et al. Up-regulated expression of ADAM17 in human colon carcinomas: co-expression with EGFR in neoplastic and endothelial cells. J Pathol 2005;207:156-163.
    • (2005) J Pathol , vol.207 , pp. 156-163
    • Blanchot-Jossic, F.1    Jarry, A.2    Masson, D.3
  • 18
    • 2542595537 scopus 로고    scopus 로고
    • Nomenclature of the finest branches of the biliary tree: Canals, ductules, and ductular reactions in human livers
    • Roskams TA, Theise ND, Balabaud C, et al. Nomenclature of the finest branches of the biliary tree: canals, ductules, and ductular reactions in human livers. Hepatology 2004;39:1739-1745.
    • (2004) Hepatology , vol.39 , pp. 1739-1745
    • Roskams, T.A.1    Theise, N.D.2    Balabaud, C.3
  • 19
    • 0025202418 scopus 로고
    • Neuroendocrine features of reactive bile ductules in cholestatic liver disease
    • Roskams TA, van den Oord JJ, De Vos R, et al. Neuroendocrine features of reactive bile ductules in cholestatic liver disease. Am J Pathol 1990;137:1019-1025.
    • (1990) Am J Pathol , vol.137 , pp. 1019-1025
    • Roskams, T.A.1    van den Oord, J.J.2    De Vos, R.3
  • 20
    • 33947409989 scopus 로고    scopus 로고
    • Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver
    • Zhou H, Rogler LE, Teperman L, et al. Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver. Hepatology 2007;45:716-724.
    • (2007) Hepatology , vol.45 , pp. 716-724
    • Zhou, H.1    Rogler, L.E.2    Teperman, L.3
  • 21
    • 0021513831 scopus 로고
    • A 135 kDa membrane protein of intercellular adherens junctions
    • Volk T, Geiger B. A 135 kDa membrane protein of intercellular adherens junctions. EMBO J 1984;3:2249-2260.
    • (1984) EMBO J , vol.3 , pp. 2249-2260
    • Volk, T.1    Geiger, B.2
  • 22
    • 0025777608 scopus 로고
    • Morphological evidence that ACAM is a major intercellular adhesion molecule in human kidney
    • Biddlestone L, Fleming S. Morphological evidence that ACAM is a major intercellular adhesion molecule in human kidney. J Pathol 1991;164:9-15.
    • (1991) J Pathol , vol.164 , pp. 9-15
    • Biddlestone, L.1    Fleming, S.2
  • 23
    • 33744899335 scopus 로고    scopus 로고
    • Characterization of sequential N-cadherin cleavage by ADAM10 and PS1
    • Uemura K, Kihara T, Kuzuya A, et al. Characterization of sequential N-cadherin cleavage by ADAM10 and PS1. Neurosci Lett 2006;402:278-283.
    • (2006) Neurosci Lett , vol.402 , pp. 278-283
    • Uemura, K.1    Kihara, T.2    Kuzuya, A.3
  • 24
    • 15444371289 scopus 로고    scopus 로고
    • ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and β-catenin nuclear signalling
    • Reiss K, Maretzky T, Ludwig A, et al. ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and β-catenin nuclear signalling. EMBO J 2005;24:742-752.
    • (2005) EMBO J , vol.24 , pp. 742-752
    • Reiss, K.1    Maretzky, T.2    Ludwig, A.3
  • 25
    • 0000968274 scopus 로고
    • Embryology of the liver and intrahepatic biliary tract, and an overview of malformations of the bile duct
    • MacIntyre N, Benhamou JP, Bircher J, Rizzeto M, Rodes J eds, Oxford Oxford University Press: Oxford
    • Desmet V. Embryology of the liver and intrahepatic biliary tract, and an overview of malformations of the bile duct. In: MacIntyre N, Benhamou JP, Bircher J, Rizzeto M, Rodes J (eds). Oxford Textbook of Clinical Hepatology, Vol. 1 Oxford University Press: Oxford, 1991, pp 497-501.
    • (1991) Textbook of Clinical Hepatology , vol.1 , pp. 497-501
    • Desmet, V.1
  • 26
    • 0031047578 scopus 로고    scopus 로고
    • The plasma membrane polarity of human biliary epithelial cells: In situ immunohistochemical analysis and functional implications
    • Scoazec JY, Bringuier AF, Medina JF, et al. The plasma membrane polarity of human biliary epithelial cells: in situ immunohistochemical analysis and functional implications. J Hepatol 1997;26:543-553.
    • (1997) J Hepatol , vol.26 , pp. 543-553
    • Scoazec, J.Y.1    Bringuier, A.F.2    Medina, J.F.3
  • 27
    • 0029929328 scopus 로고    scopus 로고
    • Identification of bipotential progenitor cells in human liver development
    • Haruna Y, Saito K, Spaulding S, et al. Identification of bipotential progenitor cells in human liver development. Hepatology 1996;23:476-481.
    • (1996) Hepatology , vol.23 , pp. 476-481
    • Haruna, Y.1    Saito, K.2    Spaulding, S.3
  • 28
    • 1442330985 scopus 로고    scopus 로고
    • MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma - mass forming type
    • Shibahara H, Tamada S, Higashi M, et al. MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma - mass forming type. Hepatology 2004;39:220-229.
    • (2004) Hepatology , vol.39 , pp. 220-229
    • Shibahara, H.1    Tamada, S.2    Higashi, M.3
  • 29
    • 0027963180 scopus 로고
    • Primary vs metastatic hepatic carcinoma. An immunohistochemical study of 34 cases
    • Fucich LF, Cheles MK, Thung SN, et al. Primary vs metastatic hepatic carcinoma. An immunohistochemical study of 34 cases. Arch Pathol Lab Med 1994;118:927-930.
    • (1994) Arch Pathol Lab Med , vol.118 , pp. 927-930
    • Fucich, L.F.1    Cheles, M.K.2    Thung, S.N.3
  • 30
    • 3042618951 scopus 로고    scopus 로고
    • N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma
    • Nakajima S, Doi R, Toyoda E, et al. N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma. Clin Cancer Res 2004;10:4125-4133.
    • (2004) Clin Cancer Res , vol.10 , pp. 4125-4133
    • Nakajima, S.1    Doi, R.2    Toyoda, E.3
  • 31
    • 0034783817 scopus 로고    scopus 로고
    • Co-expression of N-cadherin and alpha-fetoprotein in stomach cancer
    • Yanagimoto K, Sato Y, Shimoyama Y, et al. Co-expression of N-cadherin and alpha-fetoprotein in stomach cancer. Pathol Int 2001;51:612-618.
    • (2001) Pathol Int , vol.51 , pp. 612-618
    • Yanagimoto, K.1    Sato, Y.2    Shimoyama, Y.3
  • 32
    • 33645551138 scopus 로고    scopus 로고
    • The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin
    • Durnez A, Verslype C, Nevens F, et al. The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin. Histopathology 2006;49:138-151.
    • (2006) Histopathology , vol.49 , pp. 138-151
    • Durnez, A.1    Verslype, C.2    Nevens, F.3
  • 33
    • 0027857105 scopus 로고
    • Hepatocyte paraffin 1: A monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors
    • Wennerberg AE, Nalesnik MA, Coleman WB. Hepatocyte paraffin 1: a monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors. Am J Pathol 1993;143:1050-1054.
    • (1993) Am J Pathol , vol.143 , pp. 1050-1054
    • Wennerberg, A.E.1    Nalesnik, M.A.2    Coleman, W.B.3
  • 34
    • 37549050204 scopus 로고    scopus 로고
    • The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1
    • Butler SL, Dong H, Cardona D, et al. The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. Lab Invest 2008;88:78-88.
    • (2008) Lab Invest , vol.88 , pp. 78-88
    • Butler, S.L.1    Dong, H.2    Cardona, D.3
  • 35
    • 0031795529 scopus 로고    scopus 로고
    • Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular from cholangiocarcinoma, combined tumours and metastatic carcinoma
    • Leong ASY, Sormunen RT, Tsui WMS, et al. Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular from cholangiocarcinoma, combined tumours and metastatic carcinoma. Histopathology 1998;33:318-324.
    • (1998) Histopathology , vol.33 , pp. 318-324
    • Leong, A.S.Y.1    Sormunen, R.T.2    Tsui, W.M.S.3
  • 36
    • 0036328615 scopus 로고    scopus 로고
    • Hepatocyte antigen as a marker of hepatocellular carcinoma: An immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein
    • Chu PG, Ishizawa S, Wu E, et al. Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein. Am J Surg Pathol 2002;26:978-988.
    • (2002) Am J Surg Pathol , vol.26 , pp. 978-988
    • Chu, P.G.1    Ishizawa, S.2    Wu, E.3


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