Experimental verification of T-matrix-based inverse light scattering analysis for assessing structure of spheroids as models of cell nuclei

Applied Optics

Volumn 48, Issue 10, 2009, Pages

  Amoozegar, Cyrus ^a   Giacomelli, Michael G ^a   Keener, Justin D ^a   Chalut, Kevin J ^a   Wax, Adam ^a  

^a Duke University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS; INTERFEROMETRY; INVERSE PROBLEMS; LIGHT SCATTERING; MATRIX ALGEBRA; NUMERICAL METHODS;

ANGLE-RESOLVED LIGHT SCATTERING; EXPERIMENTAL VERIFICATION; INCIDENT POLARIZATION; LIGHT SCATTERING DATA; LIGHT SCATTERING MODEL; LOW COHERENCE INTERFEROMETRY; NUMERICAL IMPLEMENTATION; SCATTERING DISTRIBUTIONS;

COHERENT SCATTERING;

MICROSPHERE;

ALGORITHM; ARTICLE; AUDIOVISUAL EQUIPMENT; CELL NUCLEUS; COMPARATIVE STUDY; IMAGE QUALITY; INTERFEROMETRY; LIGHT; METHODOLOGY; MULTICELLULAR SPHEROID; RADIATION SCATTERING; REFRACTOMETRY; THEORETICAL MODEL; ULTRASTRUCTURE; VALIDATION STUDY;

ALGORITHMS; CELL NUCLEUS; INTERFEROMETRY; LIGHT; MICROSPHERES; MODELS, ANATOMIC; MODELS, THEORETICAL; PHANTOMS, IMAGING; REFRACTOMETRY; SCATTERING, RADIATION; SPHEROIDS, CELLULAR;

EID: 59149101958     PISSN: 1559128X     EISSN: 15394522     Source Type: Journal    
DOI: 10.1364/AO.48.000D20     Document Type: Article

References (25)

1. C. W. Boone, G. J. Kelloff, and V. E. Steele, "Natural history of intraepithelial neoplasia in humans with implications for cancer chemoprevention strategy," Cancer Res. 52, 1651-1659 (1992).
2. F. Guilak, "Compression-induced changes in the shape and volume of the chondrocyte nucleus," J. Biomech. 28, 1529-1541 (1995).
3. C. S. Chen and D. E. Ingber, "Tensegrity and mechanoregulation; from skeleton to cytoskeleton," Osteoarthritis Cartilage 7, 81-94 (1999).
4. J. W. Pyhtila, R. N. Graf, and A. Wax, "Determining nuclear morphology using an improved angle-resolved low coherence interferometry system," Opt. Express 11, 3473-3484 (2003).
5. A. Wax, C. H. Yang, V. Backman, K Badizadegan, C. W. Boone, R. R. Dasari, and M. S. Feld, "Cellular organization and substructure measured using angle-resolved low-coherence interferometry," Biophys. J. 82, 2256-2264 (2002).
6. C. F. Bohren and D. R. Huffman, Absorption and Scattering of Light by Small Particles (Wiley, 1983), Vol. xiv, p. 530.
7. J. D. Wilson, C. E. Bigelow, D. J. Calkins, and T. H. Foster, "Light scattering from intact cells reports oxidative-stress-induced mitochondrial swelling," Biophys. J. 88, 2929-2938 (2005).
8. V. Backman, R. Gurjar, K. Badizadegan, L. Itzkan, R. R. Dasari, L. T. Perelman, and M. S. Feld, "Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ," IEEE J. Sel. Top. Quantum Electron. 5, 1019-1026 (1999).
9. I. J. Bigio, S. G. Bown, G. Briggs, C. Kelley, S. Lakhani, D. Pickard, P. M. Ripley, I. G. Rose, and C. Saunders, "Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results," J. Biomed. Opt. 5, 221-228 (2000).
10. K. Sokolov, J. Galvan, A. Myakov, A. Lacy, R. Lotan, and R. Richards-Kortum, "Realistic three-dimensional epithelial tissue phantoms for biomedical optics," J Biomed. Opt. 7, 148-156 (2002).
11. J. D. Wilson, B. R. Giesselman, S. Mitra, and T H. Foster, " Lysosome-damage-induced scattering changes coincide with release of cytochrome c.," Opt Lett 32, 2517-2519 (2007).
12. K. J. Chalut, L. A. Kresty, J. W. Pyhtila, R. Nines, M. Baird, V. E. Steele, and A. Wax, "In Situ assessment of intraepithelial neoplasia in hamster trachea epithelium using angle-resolved low-coherence interferometry.," Cancer Epidemiol Biomarkers Prev. 16, 223-227 (2007).
13. A. Wax, C. H. Yang, M. G. Muller, R. Nines, C. W. Boon, V. E. Steele, G. D. Stoner, R. R. Dasari, and M. S. Feld, "In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry," Cancer Res. 63, 3556-3559 (2003).
14. A. Wax, J. W. Pyhtila, R. N. Graf, R. Nines, and C. W. Boone, "Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry," J Biomed. Opt. 10, 051604 (2005).
15. M. I. Mishchenko, L. D. Travis, and J. W Hovenier, Light Scattering by Nonspherical Particles: Theory, Measurements and Applications (Academic, 2000).
16. N. V. Voshchinnikov, V. B. Il'in, T. Henning, B. Michel, and V. G. Farafonov, "Extinction and polarization of radiation by absorbing spheroids: shape/size effects and benchmark results," J. Quant. Spectrosc. Radiat. Transfer 65, 877-893 (2000).
17. A. M. K. Nilsson, P. Alsholm, A. Karlsson, and S. Andersson-Engels, "T-matrix computations of light scattering by red blood cells," Appl. Opt. 37, 2735-2748 (1998).
18. J. R. Mourant, T. M. Johnson, S. Carpenter, A. Guerra, T. Aida, and J. P. Freyer, "Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures," J. Biomed. Opt. 7, 378-387 (2002).
19. D. D. Duncan and M. E. Thomas, "Particle shape as revealed by spectral depolarization," Appl Opt 46, 6185-6191 (2007).
20. J. D. Keener, K. J. Chalut, J. W. Pyhtila, and A. Wax, "Application of Mie theory to determine the structure of spheroidal scatterers in biological materials," Opt. Lett. 32, 1326-1328 (2007).
21. K J. Chalut, M. Giacomelli, and A. Wax, "Application of Mie theory to assess structure of spheroidal scattering in backscattering geometries," J. Opt. Soc. Am. A 25, 1866-1874 (2008)
22. K. J. Chalut, S. Chen, J. D. Finan, M. G. Giacomelli, F. Guilak, K W Leong, and A. Wax, "Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry," Biophys. J. 94, 4948-4956 (2008).
23. J. W. Pyhtila, K J. Chalut, J. D. Boyer, J. Keener, T. D'Amico, M. Gottfried, F. Gress, and A. Wax, "In situ detection of nuclear atypia in Barrett's esophagus using angle-resolved low coherence interferometry," Gastrointest. Endosc. 65, 487-491 (2007).
24. K. M. Keville, E. I. Franses, and J. M. Caruthers, "Preparation and characterization of monodisperse polymer microspheroids," J. Colloid Interface Sci. 144, 103-126 (1991).
25. J. W. Pyhtila, M. H., A. J. Simnick, A. Chilkoti, and A. Wax, "Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry," J. Biomed. Opt. 11, 034022 (2006).