메뉴 건너뛰기




Volumn 39, Issue 2, 2009, Pages 117-125

Evaluation of newly developed combination therapy of intra-arterial 5-fluorouracil and systemic pegylated interferon α-2b for advanced hepatocellular carcinoma with portal venous invasion: Preliminary results

Author keywords

5 fluorouracil; Hepatocellular carcinoma; PEG IFN 2b; Portalvenous invasion

Indexed keywords

FLUOROURACIL; PEGINTERFERON ALPHA2B; RIBAVIRIN; TUMOR MARKER;

EID: 59149099756     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00414.x     Document Type: Article
Times cited : (11)

References (44)
  • 1
    • 4243677965 scopus 로고
    • Diagnosis and clinical features of small hepatocellular carcinoma with emphasis on the utility of real-time ultrasonography: A study in 51 patients
    • Shinagawa T, Ohto M, Kimura K et al. Diagnosis and clinical features of small hepatocellular carcinoma with emphasis on the utility of real-time ultrasonography: A study in 51 patients. Gastroenterology 1984; 2: S21-26.
    • (1984) Gastroenterology , vol.2
    • Shinagawa, T.1    Ohto, M.2    Kimura, K.3
  • 2
    • 0022470607 scopus 로고
    • Angiography of small hepatocellular carcinomas: Analysis of 105 resected tumors
    • Takayasu K, Shima Y, Muramatsu Y et al. Angiography of small hepatocellular carcinomas: Analysis of 105 resected tumors. Am J Roentgenol 1986; 147: 525-9.
    • (1986) Am J Roentgenol , vol.147 , pp. 525-529
    • Takayasu, K.1    Shima, Y.2    Muramatsu, Y.3
  • 3
    • 0021947111 scopus 로고
    • Dynamic computed tomography during arterial portography; the most sensitive examination for hepatocellular carcinomas
    • Matsui O, Takashima T, Kadoya M et al. Dynamic computed tomography during arterial portography; the most sensitive examination for hepatocellular carcinomas. J Comput Assist Tomogr 1985; 9: 19-24.
    • (1985) J Comput Assist Tomogr , vol.9 , pp. 19-24
    • Matsui, O.1    Takashima, T.2    Kadoya, M.3
  • 4
    • 0022311965 scopus 로고
    • Transcatheter arterial embolization (TAE) in treatment for hepatoma-analysis of three-year survivors
    • Ohtomo K, Furui S, Kokubo T et al. Transcatheter arterial embolization (TAE) in treatment for hepatoma-analysis of three-year survivors. Radiat Med 1985; 3: 176-80.
    • (1985) Radiat Med , vol.3 , pp. 176-180
    • Ohtomo, K.1    Furui, S.2    Kokubo, T.3
  • 5
    • 0025356304 scopus 로고
    • Percutaneous ethanol injection therapy for treatment of hepatocellular carcinoma
    • Shiina S, Tagawa K, Unuma T et al. Percutaneous ethanol injection therapy for treatment of hepatocellular carcinoma. Am J Roentgenol 1990; 154: 947-51.
    • (1990) Am J Roentgenol , vol.154 , pp. 947-951
    • Shiina, S.1    Tagawa, K.2    Unuma, T.3
  • 6
    • 0029862896 scopus 로고    scopus 로고
    • Microwave coagulation therapy for hepatocellular carcinoma
    • Sato M, Watanabe Y, Ueda S et al. Microwave coagulation therapy for hepatocellular carcinoma. Gastroenterology 1996; 110: 1507-14.
    • (1996) Gastroenterology , vol.110 , pp. 1507-1514
    • Sato, M.1    Watanabe, Y.2    Ueda, S.3
  • 7
    • 0036294013 scopus 로고    scopus 로고
    • Nonsurgical treatment of hepatocellular carcinoma: From percutaneous ethanol injection therapy and percutaneous microwave coagulation therapy to radiofrequency ablation
    • Review
    • Shiina S, Teratani T, Obi S et al. Nonsurgical treatment of hepatocellular carcinoma: From percutaneous ethanol injection therapy and percutaneous microwave coagulation therapy to radiofrequency ablation. Oncology 2002; 62 (Suppl 1): 64-8. Review.
    • (2002) Oncology , vol.62 , Issue.SUPPL. 1 , pp. 64-68
    • Shiina, S.1    Teratani, T.2    Obi, S.3
  • 8
    • 0023939892 scopus 로고    scopus 로고
    • Treatment of cancer of the liver: Twenty years' experience with infusion and resection in 414 patients
    • Stehlin JS Jr, de Ipolyi PD, Greeff PJ et al. Treatment of cancer of the liver: Twenty years' experience with infusion and resection in 414 patients. Ann Surg 1998; 208: 23-35.
    • (1998) Ann Surg , vol.208 , pp. 23-35
    • Stehlin, J.S.1    de Ipolyi, P.D.2    Greeff, P.J.3
  • 9
    • 0023878653 scopus 로고
    • Intrahepatic chemotherapy for unresectable hepatocellular carcinoma
    • Doci R, Bignami P, Bozzetti F et al. Intrahepatic chemotherapy for unresectable hepatocellular carcinoma. Cancer 1988; 61: 1983-7.
    • (1988) Cancer , vol.61 , pp. 1983-1987
    • Doci, R.1    Bignami, P.2    Bozzetti, F.3
  • 10
    • 0016753347 scopus 로고
    • Treatment of hepatocellular carcinoma with adriamycin
    • Olweny CH, Toya T, Katongole-Mobidof F et al. Treatment of hepatocellular carcinoma with adriamycin. Cancer 1975; 36: 1250-7.
    • (1975) Cancer , vol.36 , pp. 1250-1257
    • Olweny, C.H.1    Toya, T.2    Katongole-Mobidof, F.3
  • 11
    • 0037080269 scopus 로고    scopus 로고
    • Combined intraarterial 5-fluorouracil and subcutaneous interferon-alpha therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches
    • Sakon M, Nagano H, Dono K et al. Combined intraarterial 5-fluorouracil and subcutaneous interferon-alpha therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches. Cancer 2002; 94: 435-42.
    • (2002) Cancer , vol.94 , pp. 435-442
    • Sakon, M.1    Nagano, H.2    Dono, K.3
  • 12
    • 33646383886 scopus 로고    scopus 로고
    • Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion
    • Obi S, Yoshida H, Toune R et al. Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion. Cancer 2006; 106: 1990-7.
    • (2006) Cancer , vol.106 , pp. 1990-1997
    • Obi, S.1    Yoshida, H.2    Toune, R.3
  • 13
    • 0034324083 scopus 로고    scopus 로고
    • Pegylated interferon-a2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data
    • Paul G, Jane WSF, Regine R et al. Pegylated interferon-a2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Clin Pharmacol Ther 2000; 68: 556-67.
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 556-567
    • Paul, G.1    Jane, W.S.F.2    Regine, R.3
  • 14
    • 0020396015 scopus 로고
    • Toxicity and response criteria of Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC et al. Toxicity and response criteria of Eastern Cooperative Oncology Group. Am J Clin Oncol 1982; 5: 649-55.
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 15
    • 0034770932 scopus 로고    scopus 로고
    • Intraarterial chemotherapy of liver metastasis: Implantation of microcatheter-port system with use of modified fixed catheter tip technique
    • Irie T. Intraarterial chemotherapy of liver metastasis: Implantation of microcatheter-port system with use of modified fixed catheter tip technique. J Vasc Interv Radiol 2001; 12: 1215-18.
    • (2001) J Vasc Interv Radiol , vol.12 , pp. 1215-1218
    • Irie, T.1
  • 16
    • 1842479859 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C
    • Strader DB, Wright T, Thomas DL et al. Diagnosis, management, and treatment of hepatitis C. Hepatology 2004; 39: 1147-69.
    • (2004) Hepatology , vol.39 , pp. 1147-1169
    • Strader, D.B.1    Wright, T.2    Thomas, D.L.3
  • 17
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 2000; 92: 205-16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 18
    • 33646783722 scopus 로고    scopus 로고
    • NCI Common Toxicity Criteria. [Cited 9 August 2006.] Available from URL
    • NCI Common Toxicity Criteria. Common Terminology Criteria for Adverse Events v3.0 (CTCAE). [Cited 9 August 2006.] Available from URL: http://ctep.cancer.gov/reporting/ctc.html
    • Common Terminology Criteria for Adverse Events V3.0 (CTCAE)
  • 19
    • 0027584709 scopus 로고
    • Hepatocellular carcinoma with portal tumor thrombus: Analysis of factors determining prognosis
    • Fujii T, Takayasu K, Muramatsu Y et al. Hepatocellular carcinoma with portal tumor thrombus: Analysis of factors determining prognosis. Jpn J Clin Oncol 1993; 23: 105-9.
    • (1993) Jpn J Clin Oncol , vol.23 , pp. 105-109
    • Fujii, T.1    Takayasu, K.2    Muramatsu, Y.3
  • 20
    • 0028081918 scopus 로고
    • Development of portal vein invasion and its outcome in hepatocellular carcinoma treated by transcatheter arterial chemo-embolization
    • Chen SC, Hsieh MY, Chuaug WL et al. Development of portal vein invasion and its outcome in hepatocellular carcinoma treated by transcatheter arterial chemo-embolization. J Gastroenterol Hepatol 1994; 9: 1-6.
    • (1994) J Gastroenterol Hepatol , vol.9 , pp. 1-6
    • Chen, S.C.1    Hsieh, M.Y.2    Chuaug, W.L.3
  • 21
    • 0029952414 scopus 로고    scopus 로고
    • Implications of surgical treatment for advanced hepatocellular carcinoma with tumor thrombi in the portal vein
    • Tanaka A, Morimoto T, Yamaoka Y et al. Implications of surgical treatment for advanced hepatocellular carcinoma with tumor thrombi in the portal vein. Hepatogastroenterology 1996; 43: 637-43.
    • (1996) Hepatogastroenterology , vol.43 , pp. 637-643
    • Tanaka, A.1    Morimoto, T.2    Yamaoka, Y.3
  • 22
    • 0030942752 scopus 로고    scopus 로고
    • A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein
    • Ando E, Yamashita F, Tanaka M et al. A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein. Cancer 1997; 79: 1890-6.
    • (1997) Cancer , vol.79 , pp. 1890-1896
    • Ando, E.1    Yamashita, F.2    Tanaka, M.3
  • 23
    • 0031782818 scopus 로고    scopus 로고
    • A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients
    • The Cancer of the Liver Italian Program (CLIP) Investigators
    • The Cancer of the Liver Italian Program (CLIP) Investigators. A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients. Hepatology 1998; 28: 751-5.
    • (1998) Hepatology , vol.28 , pp. 751-755
  • 24
    • 0026600296 scopus 로고
    • Stimulation of 5-fluorouracil metabolic activation by interferon-alpha in human colon carcinoma cells
    • Schwartz EL, Hoffman M, O'Connor CJ et al. Stimulation of 5-fluorouracil metabolic activation by interferon-alpha in human colon carcinoma cells. Biochem Biophys Res Commun 1992; 182: 1232-9.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1232-1239
    • Schwartz, E.L.1    Hoffman, M.2    O'Connor, C.J.3
  • 25
    • 0025293764 scopus 로고
    • Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: A review
    • Wadler S, Schwartz EL. Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: A review. Cancer Res 1990; 50: 3473-86.
    • (1990) Cancer Res , vol.50 , pp. 3473-3486
    • Wadler, S.1    Schwartz, E.L.2
  • 26
    • 0024414582 scopus 로고
    • Interferon effects upon fluorouracil metabolism by HL-60 cells
    • Elias L, Sandoval JM. Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem Biophys Res Commun 1989; 163: 867-74.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 867-874
    • Elias, L.1    Sandoval, J.M.2
  • 27
    • 19944430939 scopus 로고    scopus 로고
    • Combination of IFN-a and 5-fluorouracil induces apoptosis through IFN-a/ β receptor in human hepatocellular carcinoma cells
    • Kondo M, Nagano H, Wada H et al. Combination of IFN-a and 5-fluorouracil induces apoptosis through IFN-a/β receptor in human hepatocellular carcinoma cells. Clin Cancer Res 2005; 11: 1277-86.
    • (2005) Clin Cancer Res , vol.11 , pp. 1277-1286
    • Kondo, M.1    Nagano, H.2    Wada, H.3
  • 28
    • 0032903825 scopus 로고    scopus 로고
    • Synergistic effects of retrovirus IFN-alpha gene transfer and 5-FU on apoptosis of colon cancer cells
    • Sabaawy HE, Farley T, Ahmed T et al. Synergistic effects of retrovirus IFN-alpha gene transfer and 5-FU on apoptosis of colon cancer cells. Acta Haematol 1999; 101: 82-8.
    • (1999) Acta Haematol , vol.101 , pp. 82-88
    • Sabaawy, H.E.1    Farley, T.2    Ahmed, T.3
  • 29
    • 0032991093 scopus 로고    scopus 로고
    • Interferon alpha receptor expression and growth inhibition by interferon alpha in human liver cell lines
    • Yano H, Iemura A, Haramaki M et al. Interferon alpha receptor expression and growth inhibition by interferon alpha in human liver cell lines. Hepatology 1999; 29: 1708-17.
    • (1999) Hepatology , vol.29 , pp. 1708-1717
    • Yano, H.1    Iemura, A.2    Haramaki, M.3
  • 30
    • 0033529122 scopus 로고    scopus 로고
    • Molecular mechanisms underlying interferon alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 CDK-complexes and activation of pocket proteins
    • Sangfelt O, Erickson S, Gastro J et al. Molecular mechanisms underlying interferon alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 CDK-complexes and activation of pocket proteins. Oncogene 1999; 18: 2798-810.
    • (1999) Oncogene , vol.18 , pp. 2798-2810
    • Sangfelt, O.1    Erickson, S.2    Gastro, J.3
  • 31
    • 0026646066 scopus 로고
    • Cytokine triggered molecular pathways that control cell cycle arrest
    • Kimchi A. Cytokine triggered molecular pathways that control cell cycle arrest. J Cell Biochem 1992; 50: 1-9.
    • (1992) J Cell Biochem , vol.50 , pp. 1-9
    • Kimchi, A.1
  • 32
    • 0024566466 scopus 로고
    • Selective interferon-induced enhancement of tumor-associated antigens on a spectrum of freshly isolated human adenocarcinoma cells
    • Guadagni F, Schlom J, Johnston WW et al. Selective interferon-induced enhancement of tumor-associated antigens on a spectrum of freshly isolated human adenocarcinoma cells. J Natl Cancer Inst 1989; 81: 502-12.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 502-512
    • Guadagni, F.1    Schlom, J.2    Johnston, W.W.3
  • 33
    • 0020611528 scopus 로고
    • Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes
    • Ortaldo JR, Mantovani A, Hobbs D et al. Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes. Int J Cancer 1983; 31: 285-9.
    • (1983) Int J Cancer , vol.31 , pp. 285-289
    • Ortaldo, J.R.1    Mantovani, A.2    Hobbs, D.3
  • 34
    • 0015305466 scopus 로고
    • Enhancement by interferon of the specific cytotoxicity of sensitized lymphocytes
    • Lindahl P, Leary R, Gresser I. Enhancement by interferon of the specific cytotoxicity of sensitized lymphocytes. Proc Natl Acad Sci USA 1972; 69: 721-5.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 721-725
    • Lindahl, P.1    Leary, R.2    Gresser, I.3
  • 35
    • 0021923058 scopus 로고
    • Direct and indirect effects of interferon on in vivo murine tumor cell growth
    • Uno K, Shimizu S, Ido M et al. Direct and indirect effects of interferon on in vivo murine tumor cell growth. Cancer Res 1985; 45: 1320-7.
    • (1985) Cancer Res , vol.45 , pp. 1320-1327
    • Uno, K.1    Shimizu, S.2    Ido, M.3
  • 36
    • 33748299480 scopus 로고    scopus 로고
    • Growth inhibitory effects of pegylated IFNa-2b on human liver cancer cells in vitro and in vivo
    • Yano H, Yanai Y, Momosaki S et al. Growth inhibitory effects of pegylated IFNa-2b on human liver cancer cells in vitro and in vivo. Liver Int 2006; 26: 964-75.
    • (2006) Liver Int , vol.26 , pp. 964-975
    • Yano, H.1    Yanai, Y.2    Momosaki, S.3
  • 37
    • 26244449102 scopus 로고    scopus 로고
    • Successful treatment of advanced hepatocellular carcinoma by combined administration of 5-fluorouracil and pegylated interferon α
    • Kurokohchi K, Takaguchi K, Kita K et al. Successful treatment of advanced hepatocellular carcinoma by combined administration of 5-fluorouracil and pegylated interferon α. World J Gastrol 2005; 11: 5401-3.
    • (2005) World J Gastrol , vol.11 , pp. 5401-5403
    • Kurokohchi, K.1    Takaguchi, K.2    Kita, K.3
  • 38
    • 33745713376 scopus 로고    scopus 로고
    • A randomized trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa-2b and peginterferon alfa-2a in patients with chronic hepatitis C (COMPARE)
    • Silva M, Poo J, Wagner F et al. A randomized trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa-2b and peginterferon alfa-2a in patients with chronic hepatitis C (COMPARE). J Hepatol 2006; 45: 204-13.
    • (2006) J Hepatol , vol.45 , pp. 204-213
    • Silva, M.1    Poo, J.2    Wagner, F.3
  • 39
    • 59149100586 scopus 로고    scopus 로고
    • Combination therapy of intra arterial 5FU and systemic interferon-a for advanced hepatocellular carcinoma with portal venous invasion
    • (In Japanese.)
    • Obi S, Imamura J, Kanda M et al. Combination therapy of intra arterial 5FU and systemic interferon-a for advanced hepatocellular carcinoma with portal venous invasion. Gastroenterology (Tokyo) 2006; 43: 260-8. (In Japanese.)
    • (2006) Gastroenterology (Tokyo) , vol.43 , pp. 260-268
    • Obi, S.1    Imamura, J.2    Kanda, M.3
  • 40
    • 7044236793 scopus 로고    scopus 로고
    • Review article: Pegylated interferons: Chemical and clinical differences
    • Foster GR. ReviewCarticle: Pegylated interferons: chemical and clinical differences. Aliment Pharmacol Ther 2004; 20: 825-30.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 825-830
    • Foster, G.R.1
  • 41
    • 0022320030 scopus 로고
    • Cellular basis for the inefficacy of 5-FU in human colon carcinoma
    • Drewinko B, Yang L-Y. Cellular basis for the inefficacy of 5-FU in human colon carcinoma. Cancer Treat Rep 1985; 69: 1391-8.
    • (1985) Cancer Treat Rep , vol.69 , pp. 1391-1398
    • Drewinko, B.1    Yang, L.-Y.2
  • 42
    • 0031956281 scopus 로고    scopus 로고
    • Apoptosis-and necrosis-inducing potential of cladribine, cytarabine, cisplatin, and 5-fluorouracil in vitro: A quantitative pharmacodynamic model
    • Guchelaar HJ, Vermes I, Koopmans RP et al. Apoptosis-and necrosis-inducing potential of cladribine, cytarabine, cisplatin, and 5-fluorouracil in vitro: A quantitative pharmacodynamic model. Cancer Chemother Pharmacol 1998; 42: 77-83.
    • (1998) Cancer Chemother Pharmacol , vol.42 , pp. 77-83
    • Guchelaar, H.J.1    Vermes, I.2    Koopmans, R.P.3
  • 43
    • 59149094025 scopus 로고    scopus 로고
    • Breakthrough of the hepatic arterial infusion chemotherapy of hepatocellular carcinoma
    • (In Japanese.)
    • Ueshima K, Tatsumi C, Sakaguchi Y et al. Breakthrough of the hepatic arterial infusion chemotherapy of hepatocellular carcinoma. Gastroenterology (Tokyo) 2006; 43: 253-9. (In Japanese.)
    • (2006) Gastroenterology (Tokyo) , vol.43 , pp. 253-259
    • Ueshima, K.1    Tatsumi, C.2    Sakaguchi, Y.3
  • 44
    • 0038440794 scopus 로고    scopus 로고
    • Ribavirin and alpha interferon enhance death receptor-mediated apoptosis and caspase activation in human hepatoma cells
    • Stephan FS, Markus S, Christoph PB et al. Ribavirin and alpha interferon enhance death receptor-mediated apoptosis and caspase activation in human hepatoma cells. Antimicrob Agents Chemother 2003; 47: 1912-21.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1912-1921
    • Stephan, F.S.1    Markus, S.2    Christoph, P.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.