Kinetics and thermodynamics of metal-loaded transferrins: Transferrin receptor 1 interactions

Biochemical Society Transactions

Volumn 36, Issue 6, 2008, Pages 1422-1426

  Ha Duong, Nguyêt Thanh ^a   Hémadi, Miryana ^a   Chikh, Zohra ^a   Chahine, Jean Michel El Hage ^a  

^a UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

Fast kinetics; Iron acquisition; Protein protein interaction; Thermodynamics; Transferrin; Transferrin receptor 1

Indexed keywords

ALUMINUM; BISMUTH; CD71 ANTIGEN; COBALT; GALLIUM; IRON; METAL; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING KINETICS; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENDOCYTOSIS; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; THERMODYNAMICS; CHEMISTRY; HUMAN; KINETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE;

BINDING, COMPETITIVE; HUMANS; KINETICS; METALS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TRANSFERRIN; THERMODYNAMICS; TRANSFERRIN;

EID: 59149097402     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0361422     Document Type: Article

References (33)

1. Hentze, M.W., Muckenthaler, M.U. and Andrews, N.C. (2004) Balancing acts: molecular control of mammalian iron metabolism. Cell 117, 285-297
2. Crichton, R.R. (2001) Inorganic Biochemistry of iron Metabolism: from molecular Mechanisms to Clinical Consequences, 2nd edn, J. Wiley & Sons., Chichester
3. MacGillivray, R.T., Mendez, E., Shewale, J.G., Sinha, S.K., Lineback-Zins, J. and Brew, K. (1983) The primary structure of human serum transferrin. J. Biol. Chem. 258, 3543-3553
4. Zuccola, H.J. (1992) The Crystal Structure of Monoferric Human Serum Transfenin. Ph.D. Thesis, Georgia Institute of Technology, Atlanta, GA, U.S.A.
5. Wally, J., Halbrooks, P.J., Vonrhein, C., Rould, M.A., Everse, S.J., Mason, A. B. and Buchanan, S.K. (2006) The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding. J. Biol. Chem. 281, 24934-24944
6. Lawrence, C.M., Ray, S., Babyonyshev, M., Galluser, R., Borhani, D.W. and Harrison, S.C. (1999) Crystal structure of the ectodomain of human transferrin receptor. Science 286, 779-782
7. Hémadi, M., Kahn, P.H., Miquel, G. and El Hage Chahine, J.M. (2004) Transferrin's mechanism of interaction with receptor 1. Biochemistry 43, 1736-1745
8. Hémadi, M., Ha-Duong, NT and El Hage Chahine, J.M. (2006) The mechanism of iron release from the transferrin-receptof 1 adduct. J. Mol. Biol. 358, 1125-1136
9. Dautry-Varsat, A., Ciechanover, A. and Lodish, H.F. (1983) pH and the recycling of transferrin during ieceptor-mediated endocytosis. Proc. Natl. Acad. Sci. U.S.A., 80, 2258-2262
10. Shelf, D., Pelletier, L., O'Connell, C.B., Warren, G. and Mellman, I. (2002) Transferrin receptor recycling in the absence of perinuclear recycling endosomes. J. Cell. Biol. 156, 797-804
11. Sun, H., Li, H. and Sadler, P.J. (1999) Transferrin as a metal ion mediator. Chem. Rev. 99, 2817-2842
12. Aisen, P., Aasa, R. and Redfield, A.G. (1969) The chromium, manganese, and cobalt complexes of transferrin. J. Biol. Chem. 244, 4628-4633
13. Tinoco, A.D., Eames, E.V. and Valentine, A.M. (2008) Reconsideration of serum Ti(IV) transport: albumin and transferrin trafficking of Ti(IV) and its complexes. J. Am Chem. Soc. 130, 2262-2270
14. 2+ to apotransferrin: can this protein account for entry of uranium into human cells? Biochemistry 46, 2215-2226
15. Bernstein, L.R. (1998) Mechanisms of therapeutic activity for gallium, Pharmacol. Rev. 50, 665-682
16. Shreeve, W.W. (2007) Use of isotopes in the diagnosis of hematopoietic disorders. Exp. Hematol. 35, 173-179
17. Manyak, M.J. (2008) Indium-111 capromab pendetide in the management of recurrent prostate cancer. Expert Rev. Anticancer Ther. 8, 175-181
18. Ward, R.J., Zhang, Y. and Crichton, R.R. (2001) Aluminium toxicity and iron homeostasis. J. Inorg. Biochem. 87, 9-14
19. Krewski, D., Yokel, R.A., Nieboer, E., Borchelt, D., Cohen, J., Harry, J., Kacew, S., Lindsay, J., Mahfouz, A.M. and Rondeau, V. (2007) Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide. J. Toxicol. Environ. Health B Crit. Rev. 10 (Suppl. 1), 1-269
20. Timerbaev, A.R., Foteeva, L.S., Rudnev, A.V., Abramski, J.K., Polec-Pawlak, K., Hartinger, C.G., Jarosz, M. and Keppler, B.K. (2007) Probing the stability of serum protein-ruthenium(III) drug adducts in the presence of extracellular reductants using CE. Electrophoresis 28, 2235-2240
21. Jakupec, M.A., Galanski, M., Arion, V.B., Hartinger, C.G. and Keppler, B.K. (2008) Antitumour metal compounds: more than theme and variations. Dalton Trans. 183-194
22. Hobdy, E. and Murren, J. (2004) AN-9 (Titan). Curr. Opin. Investig. Drugs 5, 628-634
23. Bernasconi, C.F. (1976) Relaxation Kinetics, Academic Press, New York
24. Eigen, M. and DeMaeyer, L. (1963) Relaxation methods. Tech. Org. Chem. 8, 895-1029
25. Pakdaman, R., Abdallah, F.B. and El Hage Chahine, J.M. (1999) Transferrin, is a mixed chelate-protein ternary complex involved in the mechanism of iron uptake by serum-transferrin in vitro? J. Mol. Biol. 293, 1273-1284
26. Hémadi, M., Miquel, G., Kahn, P.H. and El Hage Chahine, J.M. (2003) Aluminium exchange between citrate and human serum transferrin and interaction with transferrin receptor 1. Biochemistry 42, 3120-3130
27. Miquel, G., Nekaa, T., Kahn, P.H., Hémadi, M. and El Hage Chahine, J.M. (2004) Mechanism of formation of the complex between transferrin and bismuth, and interaction with transferrin receptor 1. Biochemistry 43, 14722-14731
28. Chikh, Z., Ha-Duong, N.T., Miquel, G. and El Hage Chahine, J.M. (2007) Gallium uptake by transferrin and interaction with receptor 1. J. Biol. Inorg. Chem. 12, 90-100
29. Chikh, Z., Hémadi, M., Miquel, G., Ha-Duong, N.T. and El Hage Chahine, J.M. (2008) Cobalt and the iron acquisition pathway: competition towards interaction with receptor 1. J. Mol. Biol. 380, 900-916
30. Makey, D.G. and Seal, U.S. (1976) The detection of four molecular forms of human transferrin during the iron binding process. Biochim. Biophys. Acta 453, 250-256
31. Turkewitz, A.P., Amatruda, J.F., Borhani, D., Harrison, S.C. and Schwartz, A.L. (1988) A high yield purification of the human transferrin receptor and properties of its major extracellular fragment. J. Biol. Chem. 263, 8318-8325
32. Fuchs, H., Gessner, R., Tauber, R. and Ghosh, R. (1995) Functionnal reconstitution of the human placental transferrin receptor into phospholipid bilayers leads to long tubular structures proceeding from vesicle surface. Biochemistry 34, 6196-6207
33. Cheng, Y., Zak, O., Aisen, P., Harrison, S.C. and Walz, T. (2004) Structure of the human transferrin receptor-transferrin complex. Cell 116, 565-576