A Prospective Feasibility Trial Investigating the Use of the Impella 2.5 System in Patients Undergoing High-Risk Percutaneous Coronary Intervention (The PROTECT I Trial). Initial U.S. Experience

JACC: Cardiovascular Interventions

Volumn 2, Issue 2, 2009, Pages 91-96

  Dixon, Simon R ^a   Henriques, José P S ^b   Mauri, Laura ^c   Sjauw, Krischan ^b   Civitello, Andrew ^d   Kar, Biswajit ^d   Loyalka, Pranav ^d   Resnic, Frederic S ^c   Teirstein, Paul ^e   Makkar, Raj ^f   Palacios, Igor F ^g   Collins, Michael ^h   Moses, Jeffrey ^h   Benali, Karim ⁱ   O'Neill, William W ^j  

^a WILLIAM BEAUMONT HOSPITAL   (United States)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d TEXAS HEART INSTITUTE   (United States)

^e SCRIPPS CLINIC   (United States)

^f CEDARS SINAI MEDICAL CENTER   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h New York Presbyterian Hospital Columbia University Medical Center   (United States)

ⁱ Abiomed   (United States)

^j UNIVERSITY OF MIAMI   (United States)

more..

Author keywords

circulatory support; high risk; percutaneous coronary intervention

Indexed keywords

ADULT; AGED; ARTICLE; ASSISTED CIRCULATION; CARDIOGENIC SHOCK; CLINICAL ARTICLE; CLINICAL TRIAL; CORONARY ARTERY; DISEASE SEVERITY; FEASIBILITY STUDY; FEMALE; HEART ASSIST DEVICE; HEART HEMODYNAMICS; HEART INFARCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEMOLYSIS; HIGH RISK PATIENT; HUMAN; MALE; MEAN ARTERIAL PRESSURE; MULTICENTER STUDY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SAFETY; ST SEGMENT ELEVATION; SYSTEMIC CIRCULATION; BODY MASS; CORONARY ARTERY DISEASE; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEMODYNAMICS; MIDDLE AGED; RISK ASSESSMENT; RISK FACTOR; TRANSLUMINAL CORONARY ANGIOPLASTY; UNITED STATES; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BODY MASS INDEX; CORONARY ARTERY DISEASE; FEASIBILITY STUDIES; FEMALE; HEMODYNAMICS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; STROKE VOLUME; UNITED STATES; VENTRICULAR FUNCTION, LEFT; ANGIOPLASTY, BALLOON, CORONARY;

EID: 59149096411     PISSN: 19368798     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcin.2008.11.005     Document Type: Article

References (7)

1. Meyns B., Stolinski J., Leunens V., et al. Left ventricular support by catheter-mounted axial flow pump reduces infarct size. J Am Coll Cardiol 41 (2003) 1087-1095
2. Valgimigli M., Steendijk P., Sianos G., et al. Left ventricular unloading and concomitant total cardiac output increase by the use of percutaneous Impella Recover LP 2.5 assist device during high-risk coronary intervention. Cathet Cardiovasc Interv 65 (2005) 263-267
3. Remmelink M., Sjauw K.D., Henriques J.P., et al. Effects of left ventricular unloading by Impella Recover LP 2.5 on coronary hemodynamics. Cathet Cardiovasc Interv 70 (2007) 532-537
4. Siegenthaler M.P., Brehm K., Strecker T., et al. The Impella Recover microaxial left ventricular assist device reduces mortality for postcardiotomy failure: a three-center experience. J Thorac Cardiovasc Surg 127 (2004) 812-822
5. Strecker T., Fischlein T., and Pfeiffer S. Impella Recover 100: successful perioperative support for off pump coronary artery bypass grafting surgery in a patient with end-stage ischemic cardiomyopathy. J Cardiovasc Surg 45 (2004) 381-384
6. Meyns B., Dens J., Sergeant P., et al. Initial experiences with the Impella device in patients with cardiogenic shock-Impella support for cardiogenic shock. Thorac Cardiovasc Surg 51 (2003) 312-317
7. Henriques J.P.S., Remmelink M., Baan J., et al. Safety and feasibility of elective high-risk percutaneous coronary intervention procedures with left ventricular support of the Impella Recover LP 2.5. Am J Cardiol 97 (2006) 990-992