메뉴 건너뛰기




Volumn 29, Issue SUPPL. 1, 2009, Pages 49-56

Retreatment of chronic hepatitis C: Who and how?

Author keywords

Hepatitis C; Non responders; Retreatment

Indexed keywords

ALBINTERFERON ALPHA2B; ANTIVIRUS AGENT; ERYTHROPOIETIN; INTERFERON; METFORMIN; PEGINTERFERON; PEGINTERFERON ALPHA2A; REBETRON; RIBAVIRIN; STAT C AGENT; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 59149089845     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2008.01932.x     Document Type: Conference Paper
Times cited : (13)

References (58)
  • 1
    • 0022868893 scopus 로고
    • Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report
    • Hoofnagle JH, Mullen KD, Jones DB, et al. Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med 1986; 315: 1575-8.
    • (1986) N Engl J Med , vol.315 , pp. 1575-1578
    • Hoofnagle, J.H.1    Mullen, K.D.2    Jones, D.B.3
  • 2
    • 0032585237 scopus 로고    scopus 로고
    • Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT)
    • Poynard T, Marcellin P, Lee SS, et al. Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet 1998; 352: 1426-32.
    • (1998) Lancet , vol.352 , pp. 1426-1432
    • Poynard, T.1    Marcellin, P.2    Lee, S.S.3
  • 3
    • 0032547938 scopus 로고    scopus 로고
    • Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group
    • McHutchison JG, Gordon SC, Schiff ER, et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med 1998; 339: 1485-92.
    • (1998) N Engl J Med , vol.339 , pp. 1485-1492
    • McHutchison, J.G.1    Gordon, S.C.2    Schiff, E.R.3
  • 4
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-82.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 5
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial. Lancet 2001; 358: 958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 6
    • 38649090347 scopus 로고    scopus 로고
    • Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial
    • Mangia A, Minerva N, Bacca D, et al. Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial. Hepatology 2008; 47: 43-50.
    • (2008) Hepatology , vol.47 , pp. 43-50
    • Mangia, A.1    Minerva, N.2    Bacca, D.3
  • 7
    • 1642328395 scopus 로고    scopus 로고
    • A 48-week duration of therapy with pegylated interferon alpha 2b plus ribavirin may be too short to maximize long-term response among patients infected with genotype-1 hepatitis C virus
    • Drusano GL, Preston SL. A 48-week duration of therapy with pegylated interferon alpha 2b plus ribavirin may be too short to maximize long-term response among patients infected with genotype-1 hepatitis C virus. J Infect Dis 2004; 189: 964-70.
    • (2004) J Infect Dis , vol.189 , pp. 964-970
    • Drusano, G.L.1    Preston, S.L.2
  • 8
    • 33646590308 scopus 로고    scopus 로고
    • Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon alpha-2a (40 kd)/ribavirin therapy
    • Jensen DM, Morgan TR, Marcellin P, et al. Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon alpha-2a (40 kd)/ribavirin therapy. Hepatology 2006; 43: 954-60.
    • (2006) Hepatology , vol.43 , pp. 954-960
    • Jensen, D.M.1    Morgan, T.R.2    Marcellin, P.3
  • 9
    • 48749099989 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C Type 1 and 4 patients with rapid virological response
    • Ferenci P, Laferl H Austrian Hepatitis Study Group et al. Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C Type 1 and 4 patients with rapid virological response. Gastroenterology 2008; 135: 1561.
    • (2008) Gastroenterology , vol.135 , pp. 1561
    • Ferenci, P.1    Laferl, H.2
  • 10
    • 50649099151 scopus 로고    scopus 로고
    • Rapid virological response is a more important predictor of sustained virological response (SVR) than genotype in patients with chronic hepatitis C virus infection
    • abstract 7
    • Fried MW, Hadziyannis SJ, Shiffman M, Messinger D. Rapid virological response is a more important predictor of sustained virological response (SVR) than genotype in patients with chronic hepatitis C virus infection. J Hepatol 2008; 48(Suppl. 2): S5, abstract 7.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.3    Messinger, D.4
  • 11
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • PEGASYS International Study Group et al
    • Hadziyannis SJ, Sette Jr PEGASYS International Study Group et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette, Jr.2
  • 12
    • 33750369259 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40KD) plus ribavirin in chronic hepatitis C patients who failed previous interferon therapy
    • Canadian Pegasys Study Group et al
    • Sherman M, Yoshida EM Canadian Pegasys Study Group et al. Peginterferon alfa-2a (40KD) plus ribavirin in chronic hepatitis C patients who failed previous interferon therapy. Gut 2006; 55: 1631-8.
    • (2006) Gut , vol.55 , pp. 1631-1638
    • Sherman, M.1    Yoshida, E.M.2
  • 13
    • 12844279849 scopus 로고    scopus 로고
    • High-dose ribavirin in combination with standard dose peginterferon for treatment of patients with chronic hepatitis C
    • Lindahl K, Stahle L, Bruchfeld A, Schvarcz R. High-dose ribavirin in combination with standard dose peginterferon for treatment of patients with chronic hepatitis C. Hepatology 2005; 41: 275-9.
    • (2005) Hepatology , vol.41 , pp. 275-279
    • Lindahl, K.1    Stahle, L.2    Bruchfeld, A.3    Schvarcz, R.4
  • 14
    • 34548319085 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C virus genotype 1 with peginterferon, ribavirin, and epoetin alpha
    • Shiffman ML, Salvatore J, Hubbard S, et al. Treatment of chronic hepatitis C virus genotype 1 with peginterferon, ribavirin, and epoetin alpha. Hepatology 2007; 46: 371-9.
    • (2007) Hepatology , vol.46 , pp. 371-379
    • Shiffman, M.L.1    Salvatore, J.2    Hubbard, S.3
  • 15
    • 33947265559 scopus 로고    scopus 로고
    • Induction versus noninduction antiviral therapy for chronic hepatitis C virus in patients with congenital coagulation disorders: A Canadian multicentre trial
    • Chatterjee A, Swain MG, Lee SS, et al. Induction versus noninduction antiviral therapy for chronic hepatitis C virus in patients with congenital coagulation disorders: A Canadian multicentre trial. Can J Gastroenterol 2007; 21: 91-5.
    • (2007) Can J Gastroenterol , vol.21 , pp. 91-95
    • Chatterjee, A.1    Swain, M.G.2    Lee, S.S.3
  • 16
    • 34548606126 scopus 로고    scopus 로고
    • Efficacy of interferon alpha-2b induction therapy before retreatment for chronic hepatitis C
    • Carr C, Hollinger FB, Yoffe B, et al. Efficacy of interferon alpha-2b induction therapy before retreatment for chronic hepatitis C. Liver Int 2007; 27: 1111-8.
    • (2007) Liver Int , vol.27 , pp. 1111-1118
    • Carr, C.1    Hollinger, F.B.2    Yoffe, B.3
  • 17
    • 54449089071 scopus 로고    scopus 로고
    • Improved outcomes in hepatitis C patients with difficult to treat characteristics: Randomized study of higher doses of peginterferon α-2a and ribavirin
    • Fried MW, Jensen D, Rodriguez-Torres M, et al. Improved outcomes in hepatitis C patients with difficult to treat characteristics: Randomized study of higher doses of peginterferon α-2a and ribavirin. Hepatology, 2008; 48: 1033.
    • (2008) Hepatology, , vol.48 , pp. 1033
    • Fried, M.W.1    Jensen, D.2    Rodriguez-Torres, M.3
  • 18
    • 58049199079 scopus 로고    scopus 로고
    • Final results of the IDEAL (individualized dosing efficacy versus flat dosing to assess optimal pegylated interferon therapy) phase IIIB study
    • abstract #991
    • Sulkowski M, Lawitz E, Shiffman ML, et al. Final results of the IDEAL (individualized dosing efficacy versus flat dosing to assess optimal pegylated interferon therapy) phase IIIB study. J Hepatol 2008; 48(Suppl. 2): S370, abstract #991.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Sulkowski, M.1    Lawitz, E.2    Shiffman, M.L.3
  • 19
    • 33645992473 scopus 로고    scopus 로고
    • Extended treatment duration for hepatitis C virus type: Comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin
    • Berg T, von Wagner M, Nasser S, et al. Extended treatment duration for hepatitis C virus type: Comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin. Gastroenterology 2006; 130: 1086-97.
    • (2006) Gastroenterology , vol.130 , pp. 1086-1097
    • Berg, T.1    von Wagner, M.2    Nasser, S.3
  • 20
    • 33746564989 scopus 로고    scopus 로고
    • Peginterferon-alfa2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment
    • TeraViC-4 Study Group et al
    • Sánchez-Tapias JM, Diago M TeraViC-4 Study Group et al. Peginterferon-alfa2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment. Gastroenterology 2006; 131: 451-60.
    • (2006) Gastroenterology , vol.131 , pp. 451-460
    • Sánchez-Tapias, J.M.1    Diago, M.2
  • 21
    • 46249087915 scopus 로고    scopus 로고
    • A randomized, prospective trial of ribavirin 400mg/day versus 800mg/day in combination with peginterferon alfa-2a in hepatitis C virus genotypes 2 and 3
    • Austrian Hepatitis Study Group et al
    • Ferenci P, Brunner H Austrian Hepatitis Study Group et al. A randomized, prospective trial of ribavirin 400mg/day versus 800mg/day in combination with peginterferon alfa-2a in hepatitis C virus genotypes 2 and 3. Hepatology 2008; 47: 1816-23.
    • (2008) Hepatology , vol.47 , pp. 1816-1823
    • Ferenci, P.1    Brunner, H.2
  • 22
    • 38649090068 scopus 로고    scopus 로고
    • Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response
    • North-C Group et al
    • Dalgard O, Bjøro K North-C Group et al. Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response. Hepatology 2008; 47: 35-42.
    • (2008) Hepatology , vol.47 , pp. 35-42
    • Dalgard, O.1    Bjøro, K.2
  • 23
    • 20544443172 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3
    • Mangia A, Santoro R, Minerva N, et al. Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3. N Engl J Med 2005; 352: 2609-17.
    • (2005) N Engl J Med , vol.352 , pp. 2609-2617
    • Mangia, A.1    Santoro, R.2    Minerva, N.3
  • 24
    • 33749360440 scopus 로고    scopus 로고
    • Effect of ribavirin in genotype 1 patients with hepatitis C responding to pegylated interferon alfa-2a plus ribavirin
    • Bronowicki JP, Ouzan D, Asselah T, et al. Effect of ribavirin in genotype 1 patients with hepatitis C responding to pegylated interferon alfa-2a plus ribavirin. Gastroenterology 2006; 131: 1040-8.
    • (2006) Gastroenterology , vol.131 , pp. 1040-1048
    • Bronowicki, J.P.1    Ouzan, D.2    Asselah, T.3
  • 25
    • 36949040347 scopus 로고    scopus 로고
    • Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3
    • Canadian Pegasys Study Group et al
    • Powis J, Peltekian KM Canadian Pegasys Study Group et al. Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3. J Viral Hepatol 2008; 15: 52-7.
    • (2008) J Viral Hepatol , vol.15 , pp. 52-57
    • Powis, J.1    Peltekian, K.M.2
  • 26
    • 0043037223 scopus 로고    scopus 로고
    • High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
    • Bressler BL, Guindi M, Tomlinson G, Heathcote J. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003; 38: 639-44.
    • (2003) Hepatology , vol.38 , pp. 639-644
    • Bressler, B.L.1    Guindi, M.2    Tomlinson, G.3    Heathcote, J.4
  • 27
    • 10744227418 scopus 로고    scopus 로고
    • The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients
    • Patton HM, Patel K, Behling C, et al. The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol 2004; 40: 484-90.
    • (2004) J Hepatol , vol.40 , pp. 484-490
    • Patton, H.M.1    Patel, K.2    Behling, C.3
  • 28
    • 15744381704 scopus 로고    scopus 로고
    • Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
    • Romero-Gómez M, Del Mar Viloria M, Andrade RJ, et al. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005; 128: 636-41.
    • (2005) Gastroenterology , vol.128 , pp. 636-641
    • Romero-Gómez, M.1    Del Mar Viloria, M.2    Andrade, R.J.3
  • 29
    • 33846463006 scopus 로고    scopus 로고
    • Race, insulin resistance and hepatic steatosis in chronic hepatitis C
    • Virahep-C Study Group et al
    • Conjeevaram HS, Kleiner DE Virahep-C Study Group et al. Race, insulin resistance and hepatic steatosis in chronic hepatitis C. Hepatology 2007; 45: 80-7.
    • (2007) Hepatology , vol.45 , pp. 80-87
    • Conjeevaram, H.S.1    Kleiner, D.E.2
  • 30
    • 34848862552 scopus 로고    scopus 로고
    • Impact of Asian race on response to combination therapy with peginterferon alfa-2a and ribavirin in chronic hepatitis C
    • Canadian Pegasys Expanded Access Group et al
    • Missiha S, Heathcote J Canadian Pegasys Expanded Access Group et al. Impact of Asian race on response to combination therapy with peginterferon alfa-2a and ribavirin in chronic hepatitis C. Am J Gastroenterol 2007; 102: 2181-8.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2181-2188
    • Missiha, S.1    Heathcote, J.2
  • 31
    • 33645114359 scopus 로고    scopus 로고
    • Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1
    • Walsh MJ, Jonsson JR, Richardson MM, et al. Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1. Gut 2006; 55: 529-35.
    • (2006) Gut , vol.55 , pp. 529-535
    • Walsh, M.J.1    Jonsson, J.R.2    Richardson, M.M.3
  • 32
    • 33144462713 scopus 로고    scopus 로고
    • Association of pretreatment serum interferon gamma inducible protein 10 levels with sustained virological response to peginterferon plus ribavirin therapy in genotype 1 infected patients with chronic hepatitis C
    • Diago M, Castellano G, García-Samaniego J, et al. Association of pretreatment serum interferon gamma inducible protein 10 levels with sustained virological response to peginterferon plus ribavirin therapy in genotype 1 infected patients with chronic hepatitis C. Gut 2006; 55: 374-9.
    • (2006) Gut , vol.55 , pp. 374-3749
    • Diago, M.1    Castellano, G.2    García-Samaniego, J.3
  • 33
  • 34
    • 19044361835 scopus 로고    scopus 로고
    • Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection
    • Chen L, Borozan I, Feld J, et al. Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection. Gastroenterology 2005; 128: 1437-44.
    • (2005) Gastroenterology , vol.128 , pp. 1437-1444
    • Chen, L.1    Borozan, I.2    Feld, J.3
  • 35
    • 36348960622 scopus 로고    scopus 로고
    • Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response
    • Feld JJ, Nanda S, Huang Y, et al. Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response. Hepatology 2007; 46: 1548-63.
    • (2007) Hepatology , vol.46 , pp. 1548-1563
    • Feld, J.J.1    Nanda, S.2    Huang, Y.3
  • 36
    • 41149156316 scopus 로고    scopus 로고
    • Liver gene expression signature to predict response to pegylated interferon plus ribavirin combination therapy in patients with chronic hepatitis C
    • Asselah T, Bieche I, Narguet S, et al. Liver gene expression signature to predict response to pegylated interferon plus ribavirin combination therapy in patients with chronic hepatitis C. Gut 2008; 57: 516-24.
    • (2008) Gut , vol.57 , pp. 516-524
    • Asselah, T.1    Bieche, I.2    Narguet, S.3
  • 37
    • 34547942089 scopus 로고    scopus 로고
    • Adherence to hepatitis C treatment in recovering heroin users maintained on methadone
    • Sylvestre DL, Clements BJ. Adherence to hepatitis C treatment in recovering heroin users maintained on methadone. Eur J Gastroenterol Hepatol 2007; 19: 741-7.
    • (2007) Eur J Gastroenterol Hepatol , vol.19 , pp. 741-747
    • Sylvestre, D.L.1    Clements, B.J.2
  • 38
    • 41149140327 scopus 로고    scopus 로고
    • Therapy of interferon-induced depression in chronic hepatitis C with citalopram: A randomised, double-blind, placebo-controlled study
    • Kraus MR, Schäfer A, Schöttker K, et al. Therapy of interferon-induced depression in chronic hepatitis C with citalopram: A randomised, double-blind, placebo-controlled study. Gut 2008; 57: 531-6.
    • (2008) Gut , vol.57 , pp. 531-536
    • Kraus, M.R.1    Schäfer, A.2    Schöttker, K.3
  • 39
    • 36549047972 scopus 로고    scopus 로고
    • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • TPL102357 Study Group et al
    • McHutchison JG, Dusheiko G TPL102357 Study Group et al. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 2007; 357: 2227-36.
    • (2007) N Engl J Med , vol.357 , pp. 2227-2236
    • McHutchison, J.G.1    Dusheiko, G.2
  • 40
    • 33646001297 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b plus ribavirin in the retreatment of interferon-ribavirin nonresponder patients
    • and the Nonresponder Retreatment Group et al
    • Taliani G, Gemignani G and the Nonresponder Retreatment Group et al. Pegylated interferon alfa-2b plus ribavirin in the retreatment of interferon-ribavirin nonresponder patients. Gastroenterology 2006; 130: 1098-1106.
    • (2006) Gastroenterology , vol.130 , pp. 1098-1106
    • Taliani, G.1    Gemignani, G.2
  • 41
    • 39549120721 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2a (40kd) plus ribavirin (RBV) in prior non-responders to pegylated interferon alfa-2b (12kd)/RBV: Final efficacy and safety outcomes of the REPEAT study
    • abstract #LB4
    • Jensen DM, Freilich B, Andreone P, et al. Pegylated interferon alfa-2a (40kd) plus ribavirin (RBV) in prior non-responders to pegylated interferon alfa-2b (12kd)/RBV: Final efficacy and safety outcomes of the REPEAT study. Hepatology 2007; 46(Suppl. 1): 80A, abstract #LB4.
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Jensen, D.M.1    Freilich, B.2    Andreone, P.3
  • 42
    • 30344483613 scopus 로고    scopus 로고
    • Treatment with daily consensus interferon (CIFN) plus ribavirin in non-responder patients with chronic hepatitis C: A randomized open-label pilot study
    • Cornberg M, Hadem J, Herrmann E, et al. Treatment with daily consensus interferon (CIFN) plus ribavirin in non-responder patients with chronic hepatitis C: A randomized open-label pilot study. J Hepatol 2006; 44: 291-301.
    • (2006) J Hepatol , vol.44 , pp. 291-301
    • Cornberg, M.1    Hadem, J.2    Herrmann, E.3
  • 43
    • 41749093958 scopus 로고    scopus 로고
    • The DIRECT trial (daily-dose consensus interferon and Ribavirin: Efficacy of combined therapy): Treatment of non-responders to previous pegylated interferon plus ribavirin: Sustained virologic response data
    • abstract #168
    • Bacon B, Regev A, Ghalib RH, et al. The DIRECT trial (daily-dose consensus interferon and Ribavirin: Efficacy of combined therapy): treatment of non-responders to previous pegylated interferon plus ribavirin: Sustained virologic response data. Hepatology 2007; 46(Suppl. 1): 311A, abstract #168.
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Bacon, B.1    Regev, A.2    Ghalib, R.H.3
  • 44
    • 33644918919 scopus 로고    scopus 로고
    • A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
    • Bain VG, Kaita KD, Yoshida EM, et al. A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients. J Hepatol 2006; 44: 671-8.
    • (2006) J Hepatol , vol.44 , pp. 671-678
    • Bain, V.G.1    Kaita, K.D.2    Yoshida, E.M.3
  • 45
    • 30344483500 scopus 로고    scopus 로고
    • A phase 2 study of Albuferon in combination with ribavirin in non-responders to prior interferon therapy for chronic hepatitis C
    • Nelson D, Rustgi V, Balan V, et al. A phase 2 study of Albuferon in combination with ribavirin in non-responders to prior interferon therapy for chronic hepatitis C. Hepatology 2005; 42(Suppl. 1): 278A.
    • (2005) Hepatology , vol.42 , Issue.SUPPL. 1
    • Nelson, D.1    Rustgi, V.2    Balan, V.3
  • 46
    • 33947362952 scopus 로고    scopus 로고
    • Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis
    • Pockros PJ, Jeffers L, Afdhal N, et al. Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis. Hepatology 2007; 45: 569-78.
    • (2007) Hepatology , vol.45 , pp. 569-578
    • Pockros, P.J.1    Jeffers, L.2    Afdhal, N.3
  • 47
    • 59149089002 scopus 로고    scopus 로고
    • Interim analysis from TRIC-1. A study of Metformin with peginterferon alfa-2a and ribavirin in treatment naïve genotype 1 chronic hepatitis C with insulin resistance
    • Romero-Gomez M, Diago M, Andrade RJ, et al. Interim analysis from TRIC-1. A study of Metformin with peginterferon alfa-2a and ribavirin in treatment naïve genotype 1 chronic hepatitis C with insulin resistance. J Hepatol 2008; 48(Suppl. 2): S375.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Romero-Gomez, M.1    Diago, M.2    Andrade, R.J.3
  • 48
    • 1242340436 scopus 로고    scopus 로고
    • Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine amniotransferate, fasting insulin and quality of life
    • Hickman IJ, Jonsson JR, Prins JB, et al. Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine amniotransferate, fasting insulin and quality of life. Gut 2004; 53: 413-9.
    • (2004) Gut , vol.53 , pp. 413-419
    • Hickman, I.J.1    Jonsson, J.R.2    Prins, J.B.3
  • 49
    • 39849089235 scopus 로고    scopus 로고
    • Prolonged antiviral therapy with peginterferon to prevent complications of advanced liver disease associated with hepatitis C: Results of the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) trial
    • abstract #LB1
    • Di Bisceglie AM, Shiffman ML, Everson GT, et al. Prolonged antiviral therapy with peginterferon to prevent complications of advanced liver disease associated with hepatitis C: Results of the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) trial. Hepatology 2007; 46: 80A, abstract #LB1.
    • (2007) Hepatology , vol.46
    • Di Bisceglie, A.M.1    Shiffman, M.L.2    Everson, G.T.3
  • 50
    • 53049097017 scopus 로고    scopus 로고
    • Colchicine versus peg-interferon alfa-2b long term therapy: Results of the 4 year co-pilot trial
    • Afdhal NH, Levine R, Brown Jr R, et al. Colchicine versus peg-interferon alfa-2b long term therapy: Results of the 4 year co-pilot trial. J Hepatol 2008; 48(Suppl. 2): S4.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Afdhal, N.H.1    Levine, R.2    Brown Jr., R.3
  • 51
    • 53049104602 scopus 로고    scopus 로고
    • A study of telaprevir (TVR) with peginterferon alfa-2a (P) and ribavirin (R) in subjects with well-documented prior P/R null response, non-response or relapse: Preliminary results
    • abstract #1000
    • Poordad F, Shiffman M, Sherman K, et al. A study of telaprevir (TVR) with peginterferon alfa-2a (P) and ribavirin (R) in subjects with well-documented prior P/R null response, non-response or relapse: preliminary results. J Hepatol 2008; 48(Suppl. 2): S374, abstract #1000.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Poordad, F.1    Shiffman, M.2    Sherman, K.3
  • 52
    • 59149084775 scopus 로고    scopus 로고
    • Role of interferon response during re-treatment of null responders with Boceprevir combination therapy: Results of phase II trial
    • abstract #162
    • Schiff E, Poordad FF, Jacobson IM, et al. Role of interferon response during re-treatment of null responders with Boceprevir combination therapy: Results of phase II trial. 221. Digestive Disease Week 2008, abstract #162.
    • (2008) Digestive Disease Week , pp. 221
    • Schiff, E.1    Poordad, F.F.2    Jacobson, I.M.3
  • 53
    • 42949111104 scopus 로고    scopus 로고
    • Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41
    • Klade CS, Wedemeyer H, Berg T, et al. Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41. Gastroenterology 2008; 134: 1385-95.
    • (2008) Gastroenterology , vol.134 , pp. 1385-1395
    • Klade, C.S.1    Wedemeyer, H.2    Berg, T.3
  • 54
    • 36348931521 scopus 로고    scopus 로고
    • Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus
    • McHutchison JG, Bacon BR, Gordon SC, et al. Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus. Hepatology 2007; 46: 1341-9.
    • (2007) Hepatology , vol.46 , pp. 1341-1349
    • McHutchison, J.G.1    Bacon, B.R.2    Gordon, S.C.3
  • 55
    • 46249129186 scopus 로고    scopus 로고
    • Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus
    • Veldt BJ, Chen W, Heathcote EJ, et al. Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus. Hepatology 2008; 47: 1856-62.
    • (2008) Hepatology , vol.47 , pp. 1856-1862
    • Veldt, B.J.1    Chen, W.2    Heathcote, E.J.3
  • 56
    • 84984548367 scopus 로고    scopus 로고
    • Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: A follow-up study in Taiwan
    • Chen CL, Yang HI, Yang WS, et al. Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: A follow-up study in Taiwan. Gastroenterology 2008; 135: 111-21.
    • (2008) Gastroenterology , vol.135 , pp. 111-121
    • Chen, C.L.1    Yang, H.I.2    Yang, W.S.3
  • 57
    • 33644844121 scopus 로고    scopus 로고
    • The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma
    • Fujita Y, Shibata A, Ogimoto I, et al. The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma. Br J Cancer 2006; 94: 737-9.
    • (2006) Br J Cancer , vol.94 , pp. 737-739
    • Fujita, Y.1    Shibata, A.2    Ogimoto, I.3
  • 58
    • 33845655924 scopus 로고    scopus 로고
    • Inverse association between coffee drinking and the risk of hepatocellular carcinoma: A case-control study in Japan
    • Tanaka K, Hara M, Sakamoto T, et al. Inverse association between coffee drinking and the risk of hepatocellular carcinoma: A case-control study in Japan. Cancer Sci 2007; 98: 214.
    • (2007) Cancer Sci , vol.98 , pp. 214
    • Tanaka, K.1    Hara, M.2    Sakamoto, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.