The clinical feature of invasive fungal infection in pediatric patients with hematologic and malignant diseases: A 10-year analysis at a single institution at Japan

Journal of Pediatric Hematology/Oncology

Volumn 30, Issue 12, 2008, Pages 886-890

  Kobayashi, Ryoji ^a,b   Kaneda, Makoto ^b   Sato, Tomonobu ^a,b   Ichikawa, Mizuho ^b   Suzuki, Daisuke ^b   Ariga, Tadashi ^b  

^a SAPPORO HOKUYU HOSPITAL   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

AML; Hematologic malignancy; Invasive fungal infection

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ANTIBIOTIC AGENT; COTRIMOXAZOLE; FLUCONAZOLE; FLUOROURACIL; ITRACONAZOLE; MICAFUNGIN; MICONAZOLE; VORICONAZOLE; ANTIFUNGAL AGENT;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; APLASTIC ANEMIA; ARTICLE; BRAIN INFECTION; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; ENDOPHTHALMITIS; FEMALE; FUNGEMIA; HEPATITIS; HUMAN; KIDNEY INFECTION; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; MYCOSIS; NEPHROBLASTOMA; NEWBORN; PATHOGENESIS; PNEUMOCYSTIS PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; PROPHYLAXIS; RISK FACTOR; SCHOOL CHILD; SOLID TUMOR; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME; BLOOD DISEASE; CLINICAL TRIAL; INCIDENCE; INFANT; JAPAN; SURVIVAL RATE; TIME;

ADOLESCENT; ADULT; ANTIFUNGAL AGENTS; CHILD; CHILD, PRESCHOOL; FEMALE; FUNGEMIA; HEMATOLOGIC NEOPLASMS; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; JAPAN; MALE; MYCOSES; RISK FACTORS; STEM CELL TRANSPLANTATION; SURVIVAL RATE; TIME FACTORS; YOUNG ADULT;

EID: 59149089046     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181864a80     Document Type: Article

References (19)

1. Frickhofen N, Kaltwasser JP, Schrezenmeier H, et al. Treatment of aplastic anemia with antithymocyte globulin and methylpredniso-lone with or without cyclosporine. N Eng J Med. 1991;324: 1297-1304.
2. Kojima S, Hibi S, Kosaka Y, et al. Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia. Blood. 2000;96:2049-2054.
3. Chandrasekar PH, Weinmann A, Shearer C. Autopsy identified infections among bone marrow transplant recipients: a clinico-pathologic study of 56 patients. Bone Marrow Transplant. 1995;16: 676-681.
4. Donnelly JP. Symptoms and diagnosis of nosocomial fungal infections-state-of-the-art. Eur J Med Res. 2003;7:192-199.
5. Erjavec Z, Verweij PE. Recent progress in the diagnosis of fungal infections in the immunocompromised host. Drug Resist Update. 2002;5:3-10.
6. Zaoutis TE, Benjamin DK, Steinbach WJ. Antifungal treatment in pediatric patients. Drug Resist Updat. 2005;8:235-245.
7. Steinbach WJ, Walsh TJ. Mycoses in pediatric patients. Infect Dis Clin North Am. 2006;20:663-678.
8. Hovi L, Saarinen-Pihkala UM, Vettenranta K, et al. Invasive fungal infections in pediatric bone marrow transplant recipients: single center experience of 10 years. Bone Marrow Transplant. 2000;26: 999-1004.
9. Benjamin DK Jr, Miller WC, Bayliff S, et al. Infections diagnosed in the first year after pediatric stem cell transplantation. Pediatr Infect Dis J. 2002;21:227-234.
10. Dvorak CC, Steinbach WJ, Brown JM, et al. Risks and outcomes of invasive fungal infections in pediatric patients undergoing allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2005; 36:621-629.
11. Rosen GP, Nielsen K, Glenn S, et al. Invasive fungal infections in pediatric oncology patients: 11-year experience at a single institution. J Pediatr Hematol Oncol. 2005;27:135-140.
12. Ascioglu S, Rex JH, de Pauw B, et al; Invasive Fungal Infections Cooperative Group of the European Organization for Research and Treatment of Cancer; Mycoses Study Group of the National Institute of Allergy and Infectious Diseases. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis. 2002;34:7-14.
13. Kobayashi R, Kaneda M, Sato T, et al. Evaluation of risk factors for invasive fungal infection after allogeneic stem cell transplantation in pediatric patients. J Pediatr Hematol Oncol. 2007;29: 786-791.
14. Kaspers GJ, Creutzig U. Pediatric acute myeloid leukemia: international progress and future directions. Leukemia. 2005;19: 2025-2029.
15. Kobayashi R, Tawa A, Hanada R, et al. Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia. Pediatr Blood Cancer. 2007;48:393-398.
16. Lehrnbecher T, Kaiser J, Varwig D, et al. Antifungal usage in children undergoing intensive treatment for acute myeloid leukemia: analysis of the multicenter clinical trial AML-BFM 93. Eur J Clin Microbiol Infect Dis. 2007;26:735-738.
17. Dini G, Castagnola E, Comoli P, et al. Infections after stem cell transplantation in children: state of the art and recommendations. Bone Marrow Transplant. 2001;28(suppl 1):S18-S21.
18. Peters M, Weiner J, Whelan G. Fungal infection associated with gastroduodenal ulceration: endoscopic and pathologic appearances. Gastroenterology. 1980;78:350-354.
19. Siwek GT, Dodgson KJ, de Magalhaes-Silverman M, et al. Invasive zygomycosis in hematopoietic stem cell transplant recipients receiving voriconazole prophylaxis. Clin Infect Dis. 2004;39: 584-587.