Treatment of intracerebral hemorrhage: What should we do now?

Current Neurology and Neuroscience Reports

Volumn 9, Issue 1, 2009, Pages 13-18

  Wang, David Z ^a   Talkad, Arun V ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPROTECTIVE AGENT;

BLOOD PRESSURE; BRAIN CIRCULATION; BRAIN HEMORRHAGE; COMPUTER ASSISTED TOMOGRAPHY; HEMATOMA; HUMAN; HYPERTENSION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; REVIEW; TREATMENT OUTCOME;

BLOOD PRESSURE; CEREBRAL HEMORRHAGE; CEREBROVASCULAR CIRCULATION; HEMATOMA; HUMANS; HYPERTENSION; MAGNETIC RESONANCE IMAGING; NEUROPROTECTIVE AGENTS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 59149084366     PISSN: 15284042     EISSN: 15346293     Source Type: Journal    
DOI: 10.1007/s11910-009-0003-z     Document Type: Article

References (50)

1. Broderick J, Connolly S, Feldmann E, et al.: Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group. Stroke 2007, 38:2001-2023. This recent update of the 1999 guidelines is the most comprehensive blueprint on the diagnosis, treatment, and management of complications in patients with ICH based on the available clinical evidence. New recommendations include surgical treatment of large cerebellar hematoma, lowered MAP range, MRI and CT as equal diagnostic imaging choices, and the end-of-life decision-making process. (Pubitemid 46850654)
2. Broderick JP, Adams HP Jr, Barsan W, et al.: Guidelines for the management of spontaneous intracerebral hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke 1999, 30:905-915. (Pubitemid 29156390)
3. Frankowski RF: Epidemiology of stroke and intracerebral hemorrhage. In Intracerebral Hematomas. Edited by Kaufman HH. New York, NY: Raven Press; 1992:1-11.
4. Russell MW, Joshi AV, Neumann PJ, et al.: Predictors of hospital length of stay and cost in patients with intracerebral hemorrhage. Neurology 2006, 67:1279-1281. (Pubitemid 44563844)
5. Qureshi AI, Tuhrim S, Roderick JP, et al.: Spontaneous intracerebral hemorrhage. N Engl J Med 2001, 344:1450-1460. (Pubitemid 32402103)
6. Hänggi D, Steiger HJ: Spontaneous intracerebral haemorrhage in adults: a literature overview. Acta Neurochir 2008, 150:371-379.
7. Nilsson OG, Lindgren A, Stahl N, et al.: Incidence of intracerebral and subarachnoid haemorrhage in southern Sweden. J Neurol Neurosurg Psychiatry 2000, 69:601-607.
8. Steiner T, Rosand J, Diringer M: Intracerebral hemorrhage associated with oral anticoagulant therapy: current practices and unresolved questions. Stroke 2006, 37:256-262. (Pubitemid 43732088)
9. Rosand J, Eckman MH, Knudsen KA, et al.: The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch Intern Med 2004, 164:880-884. (Pubitemid 38520629)
10. Flibotte JJ, Hagan N, O'Donnell J, et al.: Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 2004, 63:1059-1064. (Pubitemid 39287915)
11. Yasaka M, Minematsu K, Naritomi H, et al.: Predisposing factors for enlargement of intracerebral hemorrhage in patients treated with warfarin. Thromb Haemost 2003, 89:278-283. (Pubitemid 36227279)
12. Jiang He J, Whelton PK, Vu B, et al.: Aspirin and risk of hemorrhagic stroke: a meta-analysis of randomized controlled trials. JAMA 1998, 280:1930-1935. (Pubitemid 28559811)
13. Iso H, Jacobs DR Jr, Wentworth D, et al.: The role of statins in preventing stroke. N Engl J Med 1989, 320:904-910.
14. Labovitz DL, Boden-Albala B, Hauser WA, et al.: Lacunar infarct or deep intracerebral hemorrhage: who gets which? The Northern Manhattan Study. Neurology 2007, 68:606-608.
15. Goldstein LB, Amarenco P, Szarek M, et al.: Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study. Neurology 2008, 70:2364-2370.
16. Ogasawara K, Sakai N, Kuroiwa T, et al.: Intracranial hemorrhage associated with cerebral hyperperfusion syndrome following carotid endarterectomy and carotid artery stenting: retrospective review of 4494 patients. J Neurosurg 2007, 107:1130-1136. (Pubitemid 350255174)
17. Abou-Chebl A, Yadav JS, Reginelli JP, et al.: Intracranial hemorrhage and hyperperfusion syndrome following carotid artery stenting: risk factors, prevention, and treatment. J Am Coll Cardiol 2004, 543:1596-1601. (Pubitemid 38561339)
18. Kang HS, Han MH, Kwon OK, et al.: Intracranial hemorrhage after carotid angioplasty: a pooled analysis. J Endovasc Ther 2007, 14:77-85.
19. Koennecke HC: Cerebral microbleeds on MRI: prevalence, associations, and potential clinical implications. Neurology 2006, 66:165-171.
20. *-weighted MR images in patients with spontaneous intracerebral hemorrhage. AJNR Am J Neuroradiol 1999, 20:637-642. (Pubitemid 30429021)
21. Kidwell CS, Chalela JA, Saver JL: Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA 2004, 292:1823-1830. (Pubitemid 40169292)
22. Steiner T, Kaste M, Forsting M, et al.: Recommendations for the management of intracranial haemorrhage - part I: spontaneous intracerebral haemorrhage. The European Stroke Initiative Writing Committee and the Writing Committee for the EUSI Executive Committee. Cererbovasc Dis 2006, 22:294-316. These guidelines list a concise and complete review of all published surgical trials treating ICH. They describe the management options in treating ICH and offer recommendations on the treatment of complications of ICH and the use of antithrombotics during and after ICH. (Pubitemid 44338094)
23. Mayer SA, Brun NC, Begtrup K, et al.: Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2008, 358:2127-2137. This article presents results of the FAST trial, the largest trial using the hemostatic agent rFVIIa to treat ICH. Despite a reduction in hematoma growth, there was absolutely no difference in the study's primary end point: mortality or severe disability at 90 days among patients taking rFVIIa compared with placebo. (Pubitemid 351679599)
24. Mayer SA, Brun NC, Begtrup K, et al.: Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2005, 352:777-785.
25. Kazui S, Minematsu K, Yamamoto H, et al.: Predisposing factors to enlargement of spontaneous intracerebral hematoma. Stroke 1997, 28:2370-2375. (Pubitemid 28007634)
26. Fujii Y, Takeuchi S, Sasaki O, et al.: Multivariate analysis of predictors of hematoma enlargement in spontaneous intracerebral hemorrhage. Stroke 1998, 29:1160-1166. (Pubitemid 28265472)
27. Qureshi AI, Wilson DA, Hanley DF, et al.: No evidence for an ischemic penumbra in massive experimental intracerebral hemorrhage. Neurology 1999, 52:266-272. (Pubitemid 29059050)
28. Zazulia AR, Diringer MN, Videen TO, et al.: Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage. J Cereb Blood Flow Metab 2001, 12:804-810. (Pubitemid 32613534)
29. Kidwell C, Saver JL, Mattiello J, et al.: Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology 2001, 57:1611-1617. (Pubitemid 33055479)
30. Powers WJ, Zazulia AR, Videen TO: Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage. Neurology 2001, 57:18-24. (Pubitemid 32634845)
31. Gebel JM Jr, Janch EC, Brott TG, et al.: Natural history of perihematomal edema in patients with hyperacute spontaneous intracerebral hemorrhage. Stroke 2002, 33:2631-2635. (Pubitemid 35266434)
32. Guidelines for the Management of Severe Traumatic Brain Injury: Cerebral Perfusion Pressures. Brain Trauma Foundation: New York; 2003.
33. Feigin VL, Anderson N, Rinkel GJ, et al.: Coricosteroids for aneurysmal subarachnoid haemorrrhage and primary intracerebral haemorrhage. Cochrane Database Syst Rev 2005, (3): CD004583.
34. Thiex R, Tsirka SE: Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications. Neurosurg Focus 2007, 22:E6.
35. Bereczki D, Liu M, Prado GF, Fekete I: Cochrane report: a systematic review of mannitol therapy for acute ischemic stroke and cerebral parenchymal hemorrhage. Stroke 2000, 31:2719-2722.
36. Koenig MA, Bryan M, Lewin JL 3rd, et al.: Reversal of trnastentorial herniation with hypertonic saline. Neurology 2008, 70:1023-1029. (Pubitemid 351451321)
37. Mendelow AD, Gregson BA, Fernandes HM, et al.: Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomized trial. Lancet 2005, 9457:387-397. (Pubitemid 40179225)
38. Auer L, Deinsberger W, Niederkorn K, et al.: Endoscopic surgery versus medical treatment for spontaneous intracerebral hematoma: a randomized study. J Neurosurg 1989, 70:530-535. (Pubitemid 19100711)
39. Teernstra OP, Evers SM, Lodder J, et al.: Stereotactic treatment of intracerebral hematoma by means of plasminogen activator: a multicenter randomized controlled trial (SICHPA). Stroke 2003, 34:968-974. (Pubitemid 36402971)
40. Naval NS, Nyquist PS, Carhuapoma JR: Management of spontaneous intracerebral hemorrhage. Neurol Clin 2008, 26:373-384. (Pubitemid 351736017)
41. Prasad K, Shrivastava A: Surgery for primary supratentorial intracerebral haemorrhage. Cochrane Database Syst Rev 2000, (2): CD000200.
42. ClinicalTrials.gov: Minimally Invasive Surgery Plus rtPA for Intracerebral Hemorrhage Evacuation (MISTIE). Available at http:// clinicaltrials.gov/ct2/results?term=NCT00224770. Accessed November 12, 2008.
43. Viswanathan A, Rakich SM, Engel C, et al.: Antiplatelet use after intracerebral hemorrhage. Neurology 2006, 66:206-209. (Pubitemid 43970155)
44. Eckman MH, Rosand J, Knudsen KA: Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis. Stroke 2003, 34:1710-1716. (Pubitemid 36842632)
45. FitzMaurice E, Wendell L, Snider R: Effect of statins on intracerebral hemorrhage outcome and recurrence. Stroke 2008, 39:2151-2154.
46. Lois C, Alvarez-Buylla A: Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc Natl Acad Sci U S A 1993, 90:2074-2077. (Pubitemid 23070000)
47. Masuda T, Isobe Y, Aihara N, et al.: Increase in neurogenesis and neuroblast migration after a small intracerebral hemorrhage in rats. Neurosci Lett 2007, 425:114-119. (Pubitemid 47410368)
48. Andres RH, Guzman R, Ducray AD, et al.: Cell replacement therapy for intracerebral hemorrhage. Neurosurg Focus 2008, 24:E15.
49. Jeong SW, Chu K, Jung KH, et al.: Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage. Stroke 2003, 34:2258-2263. (Pubitemid 37099846)
50. Komblum HI: Introduction to neural stem cells. Stroke 2007, 38(2 Suppl):810-816. This article offers an up-to-date review of the use of neuroprotectant and other stem cells for treating ICH in experimental models.