Re: Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?

Journal of the National Cancer Institute

Volumn 101, Issue 2, 2009, Pages 124-125

  Block, Keith ^a,b   Koch, Amanda ^a,b   Mead, Mark ^a   Newman, Robert A ^c   Gyllenhaal, Charlotte ^a,b  

^a Institute for Integrative Cancer Research and Education   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BETA CAROTENE;

CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; COUNSELING; HEAD AND NECK CANCER; HUMAN; LETTER; MEDICAL RESEARCH; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PUBLICATION; SMOKING; SURVIVAL RATE; DIET SUPPLEMENTATION; DRUG POTENTIATION; EVIDENCE BASED MEDICINE; NEOPLASM; NOTE; RADIOTHERAPY;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; DIETARY SUPPLEMENTS; DRUG SYNERGISM; EVIDENCE-BASED MEDICINE; HUMANS; NEOPLASMS; RADIOTHERAPY;

EID: 59049105617     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djn446     Document Type: Letter

References (7)

1. Lawenda BD, Kelly KM, Ladas EJ, Sagar SM, Vickers A, Blumberg JB. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? J Natl Cancer Inst. 2008;100(11):773-783.
2. Bairati I, Meyer F, Gélinas M, et al. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. J Clin Oncol. 2005;23(24):5805-5813.
3. Bairati I, Meyer F, Jobin E, et al. Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients. Int J Cancer. 2006;119(9):2221-2224.
4. Meyer F, Bairati I, Fortin A, et al. Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: a randomized trial among head and neck cancer patients. Int J Cancer. 2008;122(7):1679-1683.
5. Dotinga R. Cancer patients should steer clear of antioxidants. HealthDay News. http://www.healthday.com/Article.asp?AID=615876. Accessed May 27, 2008.
6. Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer Treat Rev. 2007;33(5):407-418.
7. Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Int J Cancer. 2008;123(6):1227-1239