Vitamin C activity of dehydroascorbic acid in humans - Association between changes in the blood vitamin C concentration or urinary excretion after oral loading

Journal of Nutritional Science and Vitaminology

Volumn 54, Issue 4, 2008, Pages 315-320

  Tsujimura, Masaru ^a   Higasa, Shizu ^a   Nakayama, Kazuhiro ^b   Yanagisawa, Yoshiko ^b   Iwamoto, Sadahiko ^b   Kagawa, Yasuo ^a  

^a KAGAWA NUTRITION UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Ascorbic acid; Dehydroascorbic acid; Glutathione S transferase P1; Polymorphism; Vitamin C metabolism

Indexed keywords

ASCORBIC ACID; DEHYDROASCORBIC ACID; GLUTATHIONE TRANSFERASE P1; MANGANESE SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE 3; UNCLASSIFIED DRUG; VITAMIN;

ADULT; ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN EXPERIMENT; KIDNEY CLEARANCE; LOADING DRUG DOSE; NORMAL HUMAN; NUTRIENT LOADING; NUTRITIONAL VALUE; SINGLE NUCLEOTIDE POLYMORPHISM; TURNOVER TIME; URINARY EXCRETION; URINE VOLUME; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM; XENOBIOTIC METABOLISM; BLOOD; CLINICAL TRIAL; CROSSOVER PROCEDURE; ORAL DRUG ADMINISTRATION; URINE;

ADMINISTRATION, ORAL; ASCORBIC ACID; CROSS-OVER STUDIES; DEHYDROASCORBIC ACID; FEMALE; HUMANS; VITAMINS; YOUNG ADULT;

EID: 59049104581     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.54.315     Document Type: Article

References (11)

1. Tsujimura M, Watanabe S, Michinaka K, Tokuhisa S, Fujita A. 1972. Metabolism of ascorbic acid and dehydroascorbic acid in man. Vitamins 45: 136-147 (in Japanese).
2. The subdivision on resources, The Council for Science and Technology, Ministry of Education, Culture, Sports, Science and Technology, Japan. 2005. Standard Tables of Food Composition in Japan, Fifth revised and enlarged edition. National Printing Bureau, Tokyo (in Japanese).
3. Ogiri Y, Fang S, Hayami S, Fujimura A, Yamamoto K, Yaita M, Kojo S. 2002. Very low vitamin C activity of orally administered L-dehydroascorbic acid. J Agric Food Chem 50: 227-229.
4. Higasa S, Tsujimura M. 2004. Vitamin C activity of dehydro-L-ascorbic acid in ODS rats. Vitamins 78: 319-325 (in Japanese).
5. Tsujimura M, Higasa S. 2007. Vitamin C activity of L-dehydroascorbic acid in human. Time-dependent vitamin C concentration in blood and urinary excretion after the oral load. Vitamins 81: 489-496 (in Japanese).
6. Higasa S, Tsujimura M, Hiraoka M, Nakayama K, Yanagisawa Y, Iwamoto S, Kagawa Y. 2007. Polymorphism of glutathione S-transferase P1 gene affects human vitamin C metabolism. Biochem Biophys Res Commun 364: 708-713.
7. Kallner AB, Hartmann D, Hornig DH. 1981, On the requirements of ascorbic acid in man: steady-state turnover and body pool in smokers. Am J Clin Nutr 34: 1347-1355.
8. Tsujimura M, Higasa S, Kasai T. 1996. Quantitative determination of total vitamin C in foods by HPLC using 2,4-dinitrophenylhydrazine as the Internal Standard. Vitamins 70: 241-248 (in Japanese).
9. Tsujimura M, Higasa S, Aono K, Seki T. 2006. Vitamin C activity of L-dehydroascorbic Acid in human. Time-dependent vitamin C urinary excretion after the oral load. Vitamins 80: 281-285 (in Japanese).
10. Wilson JX. 2005. Regulation of vitamin C transport. Annu Rev Nutr 25: 105-125.
11. Oreopoulos DG, Lindeman RD, VanderJagt DJ, Tzamaloukas AH, Bhagavan HN, Garry PJ. 1993. Renal excretion of ascorbic acid: effect of age and sex. J Am Coll Nutr 12: 537-542.