Online preconcentration of recombinant Arg-Gly-Asp-hirudin using dynamic pH junction for analysis in human urine samples by capillary electrophoresis-mass spectrometry

Journal of Chromatography A

Volumn 1216, Issue 9, 2009, Pages 1490-1495

  Su, Shengmin ^a   Yu, Yunqiu ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

CE MS; Dynamic pH junction; Human urine; Online preconcentration; Quantitative assay; rRGD hirudin

Indexed keywords

CE-MS; DYNAMIC PH JUNCTION; HUMAN URINE; ONLINE PRECONCENTRATION; QUANTITATIVE ASSAY; RRGD-HIRUDIN;

BODY FLUIDS; CAPILLARY ELECTROPHORESIS; ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; ORGANIC ACIDS; ORGANIC POLYMERS; PHASE INTERFACES; SILICA;

FUSED SILICA;

ARGINYLGLYCYLASPARTIC ACID; FORMIC ACID; METHANOL; RECOMBINANT ARGINYLGLYCYLASPARTIC ACID HIRUDIN; RECOMBINANT HIRUDIN; SILICON DIOXIDE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; DRUG DETERMINATION; ELECTRIC POTENTIAL; ELECTROSPRAY; HUMAN; MASS SPECTROMETRY; ONLINE ANALYSIS; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; TEMPERATURE; URINALYSIS; URINE; VALIDATION PROCESS;

ELECTROPHORESIS, CAPILLARY; FORMIC ACIDS; HIRUDINS; HUMANS; HYDROGEN-ION CONCENTRATION; LEAST-SQUARES ANALYSIS; MASS SPECTROMETRY; METHANOL; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 59049093187     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.12.050     Document Type: Article

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