Combined column-mobile phase mixture statistical design optimization of high-performance liquid chromatographic analysis of multicomponent systems

Journal of Chromatography A

Volumn 1216, Issue 9, 2009, Pages 1439-1449

  Breitkreitz, Márcia C ^a   Jardim, Isabel C S F ^b   Bruns, Roy E ^b  

^a International Institute of Pharmaceutical Research   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Derringer's desirability function; HPLC; Mobile phase optimization; Response surface analysis; Split plot designs

Indexed keywords

DERRINGER'S DESIRABILITY FUNCTION; HPLC; MOBILE PHASE OPTIMIZATION; RESPONSE SURFACE ANALYSIS; SPLIT-PLOT DESIGNS;

ACETONITRILE; CHROMATOGRAPHIC ANALYSIS; DESIGN; FUNCTIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; METHANOL; MIXTURES; OPTIMIZATION; PESTICIDES; PROBABILITY DENSITY FUNCTION; SURFACE ANALYSIS; SURFACE PROPERTIES;

COLUMN CHROMATOGRAPHY;

ACETONITRILE; METHANOL; PESTICIDE; TETRAHYDROFURAN; WATER;

AQUEOUS SOLUTION; ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLUTE; STATISTICAL MODEL; VALIDATION PROCESS;

ACETONITRILES; ALGORITHMS; ANALYSIS OF VARIANCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FURANS; METHANOL; MODELS, STATISTICAL; PESTICIDES; REPRODUCIBILITY OF RESULTS;

EID: 59049083859     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.12.093     Document Type: Article

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