메뉴 건너뛰기




Volumn 52, Issue 8, 2008, Pages 1288-1295

Somatostatin receptors subtypes 2 and 5, dopamine receptor type 2 expression and gsp status as predictors of octreotide LAR® responsiveness in acromegaly

Author keywords

Acromegaly; Dopamine receptor; Octreotide LAR ; Somatostatin receptor

Indexed keywords


EID: 58949104925     PISSN: 00042730     EISSN: 16779487     Source Type: Journal    
DOI: 10.1590/s0004-27302008000800014     Document Type: Article
Times cited : (14)

References (40)
  • 2
    • 15944401695 scopus 로고    scopus 로고
    • The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical 'cure'
    • Nomikos P, Buchfelder M, Fahlbusch R. The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical 'cure'. Eur J Endocrinol. 2005;152(3):379-87.
    • (2005) Eur J Endocrinol , vol.152 , Issue.3 , pp. 379-387
    • Nomikos, P.1    Buchfelder, M.2    Fahlbusch, R.3
  • 4
    • 34347380169 scopus 로고    scopus 로고
    • A prospective, multicentre study to investigate the efficacy, safety and tolerability of octreotide LAR (long-acting repeatable octreotide) in the primary therapy of patients with acromegaly
    • Mercado M, Borges F, Bouterfa H, Chang TC, Chervin A, Farrall AJ, et al. A prospective, multicentre study to investigate the efficacy, safety and tolerability of octreotide LAR (long-acting repeatable octreotide) in the primary therapy of patients with acromegaly. Clin Endocrinol (Oxf). 2007;66(6):859-68.
    • (2007) Clin Endocrinol (Oxf) , vol.66 , Issue.6 , pp. 859-868
    • Mercado, M.1    Borges, F.2    Bouterfa, H.3    Chang, T.C.4    Chervin, A.5    Farrall, A.J.6
  • 5
    • 0029111738 scopus 로고
    • Safety and efficacy of long-term octreotide therapy of acromegaly: Results of a multicenter trial in 103 patients-a clinical research center study
    • Newman CB, Melmed S, Snyder PJ, Young WF, Boyajy LD, Levy R, et al. Safety and efficacy of long-term octreotide therapy of acromegaly: results of a multicenter trial in 103 patients-a clinical research center study. J Clin Endocrinol Metab. 1995;80(9):2768-75.
    • (1995) J Clin Endocrinol Metab , vol.80 , Issue.9 , pp. 2768-2775
    • Newman, C.B.1    Melmed, S.2    Snyder, P.J.3    Young, W.F.4    Boyajy, L.D.5    Levy, R.6
  • 6
    • 10744227971 scopus 로고    scopus 로고
    • Four-year treatment with octreotide-long-acting repeatable in 110 acromegalic patients: Predictive value of shortterm results?
    • Cozzi R, Attanasio R, Montini M, Pagani G, Lasio G, Lodrini S, et al. Four-year treatment with octreotide-long-acting repeatable in 110 acromegalic patients: predictive value of shortterm results? J Clin Endocrinol Metab. 2003;88(7):3090-8.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.7 , pp. 3090-3098
    • Cozzi, R.1    Attanasio, R.2    Montini, M.3    Pagani, G.4    Lasio, G.5    Lodrini, S.6
  • 7
    • 19944381531 scopus 로고    scopus 로고
    • Intravenous octreotide test predicts the long term outcome of treatment with octreotide-long-acting repeatable in active acromegaly
    • Biermasz NR, Pereira AM, Smit JW, Romijn JA, Roelfsema F. Intravenous octreotide test predicts the long term outcome of treatment with octreotide-long-acting repeatable in active acromegaly. Growth Horm IGF Res. 2005;15(3):200-6.
    • (2005) Growth Horm IGF Res , vol.15 , Issue.3 , pp. 200-206
    • Biermasz, N.R.1    Pereira, A.M.2    Smit, J.W.3    Romijn, J.A.4    Roelfsema, F.5
  • 9
    • 22744455955 scopus 로고    scopus 로고
    • Limited predictive value of an acute test with subcutaneous octreotide for long-term IGF-I normalization with Sandostatin LAR in acromegaly
    • de Herder WW, Taal HR, Uitterlinden P, Feelders RA, Janssen JA, van der Lely AJ. Limited predictive value of an acute test with subcutaneous octreotide for long-term IGF-I normalization with Sandostatin LAR in acromegaly. Eur J Endocrinol. 2005;153(1):67-71.
    • (2005) Eur J Endocrinol , vol.153 , Issue.1 , pp. 67-71
    • de Herder, W.W.1    Taal, H.R.2    Uitterlinden, P.3    Feelders, R.A.4    Janssen, J.A.5    van der Lely, A.J.6
  • 10
    • 19044395416 scopus 로고    scopus 로고
    • Usefulness of subcutaneous or long-acting octreotide as a predictive test and in the treatment of acromegaly]. Arq Bras Endocrinol
    • Halah FP, Elias LL, Martinelli CE, Jr., Castro M, Moreira AC. [Usefulness of subcutaneous or long-acting octreotide as a predictive test and in the treatment of acromegaly]. Arq Bras Endocrinol Metabol. 2004;48(2):245-52.
    • (2004) Metabol , vol.48 , Issue.2 , pp. 245-252
    • Halah, F.P.1    Elias, L.L.2    Martinelli Jr., C.E.3    Castro, M.4    Moreira, A.C.5
  • 11
    • 15044348198 scopus 로고    scopus 로고
    • The value of an acute octreotide suppression test in predicting long-term responses to depot somatostatin analogues in patients with active acromegaly
    • Karavitaki N, Botusan I, Radian S, Coculescu M, Turner HE, Wass JA. The value of an acute octreotide suppression test in predicting long-term responses to depot somatostatin analogues in patients with active acromegaly. Clin Endocrinol (Oxf). 2005;62(3):282-8.
    • (2005) Clin Endocrinol (Oxf) , vol.62 , Issue.3 , pp. 282-288
    • Karavitaki, N.1    Botusan, I.2    Radian, S.3    Coculescu, M.4    Turner, H.E.5    Wass, J.A.6
  • 12
    • 0023794888 scopus 로고
    • Therapy of acromegaly with sandostatin: The predictive value of an acute test, the value of serum somatomedin-C measurements in dose adjustment and the definition of a biochemical 'cure'
    • Lamberts SW, Uitterlinden P, Schuijff PC, Klijn JG. Therapy of acromegaly with sandostatin: the predictive value of an acute test, the value of serum somatomedin-C measurements in dose adjustment and the definition of a biochemical 'cure'. Clin Endocrinol (Oxf). 1988;29(4):411-20.
    • (1988) Clin Endocrinol (Oxf) , vol.29 , Issue.4 , pp. 411-420
    • Lamberts, S.W.1    Uitterlinden, P.2    Schuijff, P.C.3    Klijn, J.G.4
  • 13
    • 33644670829 scopus 로고    scopus 로고
    • Poor responses to a test dose of subcutaneous octreotide predict the need for adjuvant therapy to achieve 'safe' growth hormone levels
    • Lindsay JR, McConnell EM, Hunter SJ, McCance DR, Sheridan B, Atkinson AB. Poor responses to a test dose of subcutaneous octreotide predict the need for adjuvant therapy to achieve 'safe' growth hormone levels. Pituitary. 2004;7(3):139-44.
    • (2004) Pituitary , vol.7 , Issue.3 , pp. 139-144
    • Lindsay, J.R.1    McConnell, E.M.2    Hunter, S.J.3    McCance, D.R.4    Sheridan, B.5    Atkinson, A.B.6
  • 14
    • 33749059233 scopus 로고    scopus 로고
    • Acute test with subcutaneous octreotide as a predictor of the response to treatment with octreotide LAR]. Arq Bras Endocrinol
    • Taboada GF, Donangelo I, Guimaraes RF, Silva MO, Fontes R, Gadelha MR. [Acute test with subcutaneous octreotide as a predictor of the response to treatment with octreotide LAR]. Arq Bras Endocrinol Metabol. 2005;49(3):390-5.
    • (2005) Metabol , vol.49 , Issue.3 , pp. 390-395
    • Taboada, G.F.1    Donangelo, I.2    Guimaraes, R.F.3    Silva, M.O.4    Fontes, R.5    Gadelha, M.R.6
  • 15
    • 0030747124 scopus 로고    scopus 로고
    • 111Indium-pentetreotide pituitary scintigraphy and hormonal responses to octreotide in acromegalic patients
    • Legovini P, De Menis E, Billed D, Conti B, Zoli P, Conte N. 111Indium-pentetreotide pituitary scintigraphy and hormonal responses to octreotide in acromegalic patients. J Endocrinol Invest. 1997;20(7):424-8.
    • (1997) J Endocrinol Invest , vol.20 , Issue.7 , pp. 424-428
    • Legovini, P.1    De Menis, E.2    Billed, D.3    Conti, B.4    Zoli, P.5    Conte, N.6
  • 16
    • 1842333956 scopus 로고    scopus 로고
    • Results of somatostatin receptor scintigraphy do not predict pituitary tumor volume- and hormone-response to ocreotide therapy and do not correlate with tumor histology
    • Plockinger U, Bader M, Hopfenmuller W, Saeger W, Quabbe HJ. Results of somatostatin receptor scintigraphy do not predict pituitary tumor volume- and hormone-response to ocreotide therapy and do not correlate with tumor histology. Eur J Endocrinol. 1997;136(4):369-76.
    • (1997) Eur J Endocrinol , vol.136 , Issue.4 , pp. 369-376
    • Plockinger, U.1    Bader, M.2    Hopfenmuller, W.3    Saeger, W.4    Quabbe, H.J.5
  • 17
    • 0029618395 scopus 로고
    • In vivo responsiveness of morphological variants of growth hormone-producing pituitary adenomas to octreotide
    • Ezzat S, Kontogeorgos G, Redelmeier DA, Horvath E, Harris AG, Kovacs K. In vivo responsiveness of morphological variants of growth hormone-producing pituitary adenomas to octreotide. Eur J Endocrinol. 1995;133(6):686-90.
    • (1995) Eur J Endocrinol , vol.133 , Issue.6 , pp. 686-690
    • Ezzat, S.1    Kontogeorgos, G.2    Redelmeier, D.A.3    Horvath, E.4    Harris, A.G.5    Kovacs, K.6
  • 18
    • 39149098829 scopus 로고    scopus 로고
    • The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma
    • Fougner SL, Borota OC, Berg JP, Hald JK, Ramm-Pettersen J, Bollerslev J. The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma. Clin Endocrinol (Oxf). 2008;68(3):458-65.
    • (2008) Clin Endocrinol (Oxf) , vol.68 , Issue.3 , pp. 458-465
    • Fougner, S.L.1    Borota, O.C.2    Berg, J.P.3    Hald, J.K.4    Ramm-Pettersen, J.5    Bollerslev, J.6
  • 19
    • 40849118727 scopus 로고    scopus 로고
    • Immunohistochemical Detection of Somatostatin Receptor (SSTR) Subtypes 2A and 5 in Pituitary Adenoma from Acromegalic Patients: Good Correlation with Preoperative Response to Octreotide
    • Takei M, Suzuki M, Kajiya H, Ishii Y, Tahara S, Miyakoshi T, et al. Immunohistochemical Detection of Somatostatin Receptor (SSTR) Subtypes 2A and 5 in Pituitary Adenoma from Acromegalic Patients: Good Correlation with Preoperative Response to Octreotide. Endocr Pathol. 2007;18(4): 208-16.
    • (2007) Endocr Pathol , vol.18 , Issue.4 , pp. 208-216
    • Takei, M.1    Suzuki, M.2    Kajiya, H.3    Ishii, Y.4    Tahara, S.5    Miyakoshi, T.6
  • 21
    • 0033322617 scopus 로고    scopus 로고
    • Impact of gsp oncogene on the expression of genes coding for Gsalpha, Pit-1, Gi2alpha, and somatostatin receptor 2 in human somatotroph adenomas: Involvement in octreotide sensitivity
    • Barlier A, Pellegrini-Bouiller I, Gunz G, Zamora AJ, Jaquet P, Enjalbert A. Impact of gsp oncogene on the expression of genes coding for Gsalpha, Pit-1, Gi2alpha, and somatostatin receptor 2 in human somatotroph adenomas: involvement in octreotide sensitivity. J Clin Endocrinol Metab. 1999;84(8):2759-65.
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.8 , pp. 2759-2765
    • Barlier, A.1    Pellegrini-Bouiller, I.2    Gunz, G.3    Zamora, A.J.4    Jaquet, P.5    Enjalbert, A.6
  • 22
    • 27544470454 scopus 로고    scopus 로고
    • The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly
    • Bhayana S, Booth GL, Asa SL, Kovacs K, Ezzat S. The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly. J Clin Endocrinol Metab. 2005;90(11):6290-5.
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.11 , pp. 6290-6295
    • Bhayana, S.1    Booth, G.L.2    Asa, S.L.3    Kovacs, K.4    Ezzat, S.5
  • 23
    • 17744393215 scopus 로고    scopus 로고
    • Prevalence of Gs alpha mutations in Korean patients with pituitary adenomas
    • Kim HJ, Kim MS, Park YJ, Kim SW, Park DJ, Park KS, et al. Prevalence of Gs alpha mutations in Korean patients with pituitary adenomas. J Endocrinol. 2001;168(2):221-6.
    • (2001) J Endocrinol , vol.168 , Issue.2 , pp. 221-226
    • Kim, H.J.1    Kim, M.S.2    Park, Y.J.3    Kim, S.W.4    Park, D.J.5    Park, K.S.6
  • 24
    • 20844461864 scopus 로고    scopus 로고
    • Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: The relationship with endogenous srif activity and response to octreotide
    • Park C, Yang I, Woo J, Kim S, Kim J, Kim Y, et al. Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: the relationship with endogenous srif activity and response to octreotide. Endocr J. 2004;51(2):227-36.
    • (2004) Endocr J , vol.51 , Issue.2 , pp. 227-236
    • Park, C.1    Yang, I.2    Woo, J.3    Kim, S.4    Kim, J.5    Kim, Y.6
  • 25
    • 0025695763 scopus 로고
    • Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase
    • Spada A, Arosio M, Bochicchio D, Bazzoni N, Vallar L, Bassetti M, et al. Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase. J Clin Endocrinol Metab. 1990;71(6):1421-6.
    • (1990) J Clin Endocrinol Metab , vol.71 , Issue.6 , pp. 1421-1426
    • Spada, A.1    Arosio, M.2    Bochicchio, D.3    Bazzoni, N.4    Vallar, L.5    Bassetti, M.6
  • 26
    • 0029882954 scopus 로고    scopus 로고
    • Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients
    • Yang I, Park S, Ryu M, Woo J, Kim S, Kim J, et al. Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients. Eur J Endocrinol. 1996;134(6):720-6.
    • (1996) Eur J Endocrinol , vol.134 , Issue.6 , pp. 720-726
    • Yang, I.1    Park, S.2    Ryu, M.3    Woo, J.4    Kim, S.5    Kim, J.6
  • 27
    • 0035062749 scopus 로고    scopus 로고
    • Somatostatin receptor subtype 2 and 5 in human GH-secreting pituitary adenomas: Analysis of gene sequence and rnRNA expression
    • Corbetta S, Ballare E, Mantovani G, Lania A, Losa M, Di Blasio AM, et al. Somatostatin receptor subtype 2 and 5 in human GH-secreting pituitary adenomas: analysis of gene sequence and rnRNA expression. Eur J Clin Invest. 2001;31(3):208-14.
    • (2001) Eur J Clin Invest , vol.31 , Issue.3 , pp. 208-214
    • Corbetta, S.1    Ballare, E.2    Mantovani, G.3    Lania, A.4    Losa, M.5    Di Blasio, A.M.6
  • 28
    • 11144353578 scopus 로고    scopus 로고
    • The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro
    • Hofland LJ, van der Hoek J, van Koetsveld PM, de Herder WW, Waaijers M, Sprij-Mooij D, et al. The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro. J Clin Endocrinol Metab. 2004;89(4): 1577-85.
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.4 , pp. 1577-1585
    • Hofland, L.J.1    van der Hoek, J.2    van Koetsveld, P.M.3    de Herder, W.W.4    Waaijers, M.5    Sprij-Mooij, D.6
  • 29
    • 17744378733 scopus 로고    scopus 로고
    • Human somatostatin receptor subtypes in acromegaly: Distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes
    • Jaquet P, Saveanu A, Gunz G, Fina F, Zamora AJ, Grino M, et al. Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. J Clin Endocrinol Metab. 2000;85(2):781-92.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.2 , pp. 781-792
    • Jaquet, P.1    Saveanu, A.2    Gunz, G.3    Fina, F.4    Zamora, A.J.5    Grino, M.6
  • 30
    • 17744399907 scopus 로고    scopus 로고
    • Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas
    • Saveanu A, Gunz G, Dufour H, Caron P, Fina F, Ouafik L, et al. Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas. J Clin Endocrinol Metab. 2001;86(1):140-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.1 , pp. 140-145
    • Saveanu, A.1    Gunz, G.2    Dufour, H.3    Caron, P.4    Fina, F.5    Ouafik, L.6
  • 31
    • 33847747850 scopus 로고    scopus 로고
    • Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas
    • Taboada GF, Luque RM, Bastos W, Guimaraes RF, Marcondes JB, Chimelli LM, et al. Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas. Eur J Endocrinol. 2007;156(1):65-74.
    • (2007) Eur J Endocrinol , vol.156 , Issue.1 , pp. 65-74
    • Taboada, G.F.1    Luque, R.M.2    Bastos, W.3    Guimaraes, R.F.4    Marcondes, J.B.5    Chimelli, L.M.6
  • 32
    • 40949154229 scopus 로고    scopus 로고
    • Quantitative analysis of somatostatin receptor subtypes (1-5) gene expression levels in somatotropinomas and correlation to in vivo hormonal and tumor volume responses to treatment with octreotide LAR
    • Taboada GF, Luque RM, Neto LV, Machado Ede O, Sbaffi BC, Domingues RC, et al. Quantitative analysis of somatostatin receptor subtypes (1-5) gene expression levels in somatotropinomas and correlation to in vivo hormonal and tumor volume responses to treatment with octreotide LAR. Eur J Endocrinol. 2008;158(3):295-303.
    • (2008) Eur J Endocrinol , vol.158 , Issue.3 , pp. 295-303
    • Taboada, G.F.1    Luque, R.M.2    Neto, L.V.3    Machado Ede, O.4    Sbaffi, B.C.5    Domingues, R.C.6
  • 33
    • 0026688973 scopus 로고
    • Volume of pituitary macroadenomas: Assessment by MRI
    • Lundin P, Pedersen F. Volume of pituitary macroadenomas: assessment by MRI. J Comput Assist Tomogr. 1992;16(4):519-28.
    • (1992) J Comput Assist Tomogr , vol.16 , Issue.4 , pp. 519-528
    • Lundin, P.1    Pedersen, F.2
  • 34
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;18;3(7): RESEARCH0034.
    • (2002) Genome Biol , vol.3 , Issue.7
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 35
    • 0032252404 scopus 로고    scopus 로고
    • Activating mutations of the Gs alpha gene are associated with low levels of Gs alpha protein in growth hormone-secreting tumors
    • Ballare E, Mantovani S, Lania A, Di Blasio AM, Vallar L, Spada A. Activating mutations of the Gs alpha gene are associated with low levels of Gs alpha protein in growth hormone-secreting tumors. J Clin Endocrinol Metab. 1998;83(12):4386-90.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.12 , pp. 4386-4390
    • Ballare, E.1    Mantovani, S.2    Lania, A.3    Di Blasio, A.M.4    Vallar, L.5    Spada, A.6
  • 36
    • 0037323565 scopus 로고    scopus 로고
    • The pathophysiological consequences of somatostatin receptor internalization and resistance
    • Hofland LJ, Lamberts SW. The pathophysiological consequences of somatostatin receptor internalization and resistance. Endocr Rev. 2003;24(1):28-47.
    • (2003) Endocr Rev , vol.24 , Issue.1 , pp. 28-47
    • Hofland, L.J.1    Lamberts, S.W.2
  • 37
    • 0029791822 scopus 로고    scopus 로고
    • Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): Subtype selective internalization or upregulation
    • Hukovic N, Panetta R, Kumar U, Patel YC. Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): subtype selective internalization or upregulation. Endocrinology. 1996;137(9):4046-9.
    • (1996) Endocrinology , vol.137 , Issue.9 , pp. 4046-4049
    • Hukovic, N.1    Panetta, R.2    Kumar, U.3    Patel, Y.C.4
  • 38
    • 34548450155 scopus 로고    scopus 로고
    • Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonanceenergytransferanalysis
    • Baragli A, Alturaihi H, Watt HL, Abdallah A, Kumar U. Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonanceenergytransferanalysis. Cell Signal. 2007;19(11): 2304-16.
    • (2007) Cell Signal , vol.19 , Issue.11 , pp. 2304-2316
    • Baragli, A.1    Alturaihi, H.2    Watt, H.L.3    Abdallah, A.4    Kumar, U.5
  • 39
    • 0034616021 scopus 로고    scopus 로고
    • Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
    • Rocheville M, Lange DC, Kumar U, Patel SC, Patel RC, Patel YC. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science. 2000;288(5463):154-7.
    • (2000) Science , vol.288 , Issue.5463 , pp. 154-157
    • Rocheville, M.1    Lange, D.C.2    Kumar, U.3    Patel, S.C.4    Patel, R.C.5    Patel, Y.C.6
  • 40
    • 42149145552 scopus 로고    scopus 로고
    • Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy
    • Ferone D, de Herder WW, Pivonello R, Kros JM, van Koetsveld PM, de Jong T, et al. Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy. J Clin Endocrinol Metab. 2008;93(4):1412-7.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.4 , pp. 1412-1417
    • Ferone, D.1    de Herder, W.W.2    Pivonello, R.3    Kros, J.M.4    van Koetsveld, P.M.5    de Jong, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.