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Volumn 19, Issue 3, 2009, Pages 177-187

Electrophysiological characterization of the effects of asenapine at 5-HT1A, 5-HT2A, α2-adrenergic and D2 receptors in the rat brain

Author keywords

Asenapine; Dopamine; Electrophysiology; Norepinephrine; Schizophrenia; Serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; ALPHA 2 ADRENERGIC RECEPTOR; APOMORPHINE; ASENAPINE; CLONIDINE; DOPAMINE 2 RECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR;

EID: 58949100862     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2008.11.001     Document Type: Article
Times cited : (46)

References (58)
  • 1
    • 0018066653 scopus 로고
    • Feedback regulation of central monoaminergic neurons: evidence from single-cell recording studies
    • Aghajanian G.K. Feedback regulation of central monoaminergic neurons: evidence from single-cell recording studies. Essays Neurochem. Neuropharmacol. 3 (1978) 1-32
    • (1978) Essays Neurochem. Neuropharmacol. , vol.3 , pp. 1-32
    • Aghajanian, G.K.1
  • 2
    • 0020413359 scopus 로고
    • Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure
    • Aghajanian G.K., and Vandermaelen C.P. Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure. J. Neurosci. 2 (1982) 1786-1792
    • (1982) J. Neurosci. , vol.2 , pp. 1786-1792
    • Aghajanian, G.K.1    Vandermaelen, C.P.2
  • 3
    • 0025934933 scopus 로고
    • Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons
    • Aston-Jones G., Akaoka H., Charléty P., and Chouvet G. Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons. J. Neurosci. 11 (1991) 760-769
    • (1991) J. Neurosci. , vol.11 , pp. 760-769
    • Aston-Jones, G.1    Akaoka, H.2    Charléty, P.3    Chouvet, G.4
  • 4
    • 24144465700 scopus 로고    scopus 로고
    • Atypical antipsychotics for mood and anxiety disorders: safe and effective adjuncts?
    • Blier P. Atypical antipsychotics for mood and anxiety disorders: safe and effective adjuncts?. J. Psychiatry Neurosci. 30 (2005) 232-233
    • (2005) J. Psychiatry Neurosci. , vol.30 , pp. 232-233
    • Blier, P.1
  • 7
    • 0038653525 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of second-generation antipsychotics
    • Davis J.M., Chen N., and Glick I.D. A meta-analysis of the efficacy of second-generation antipsychotics. Arch. Gen. Psychiatry 60 (2003) 553-564
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 553-564
    • Davis, J.M.1    Chen, N.2    Glick, I.D.3
  • 8
    • 0035477920 scopus 로고    scopus 로고
    • Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity
    • Dawe G.S., Huff K.D., Vandergriff J.L., Sharp T., O'Neill M.J., and Rasmussen K. Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity. Biol. Psychiatry 50 (2001) 510-520
    • (2001) Biol. Psychiatry , vol.50 , pp. 510-520
    • Dawe, G.S.1    Huff, K.D.2    Vandergriff, J.L.3    Sharp, T.4    O'Neill, M.J.5    Rasmussen, K.6
  • 9
    • 28044469011 scopus 로고    scopus 로고
    • Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: role in atypical antipsychotic action
    • Diaz-Mataix L., Scorza M.C., Bortolozzi A., Toth M., Celada P., and Artigas F. Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: role in atypical antipsychotic action. J. Neurosci. 25 (2005) 10831-10843
    • (2005) J. Neurosci. , vol.25 , pp. 10831-10843
    • Diaz-Mataix, L.1    Scorza, M.C.2    Bortolozzi, A.3    Toth, M.4    Celada, P.5    Artigas, F.6
  • 10
    • 0035068099 scopus 로고    scopus 로고
    • Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment
    • Dong J., and Blier P. Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment. Psychopharmacology (Berl) 155 (2001) 52-57
    • (2001) Psychopharmacology (Berl) , vol.155 , pp. 52-57
    • Dong, J.1    Blier, P.2
  • 11
    • 33847275575 scopus 로고    scopus 로고
    • Noradrenergic augmentation of escitalopram response by risperidone: electrophysiologic studies in the rat brain
    • Dremencov E., El Mansari M., and Blier P. Noradrenergic augmentation of escitalopram response by risperidone: electrophysiologic studies in the rat brain. Biol. Psychiatry 61 (2007) 671-678
    • (2007) Biol. Psychiatry , vol.61 , pp. 671-678
    • Dremencov, E.1    El Mansari, M.2    Blier, P.3
  • 12
    • 34548024621 scopus 로고    scopus 로고
    • Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons
    • Dremencov E., El Mansari M., and Blier P. Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons. Psychopharmacology (Berl) 194 (2007) 63-72
    • (2007) Psychopharmacology (Berl) , vol.194 , pp. 63-72
    • Dremencov, E.1    El Mansari, M.2    Blier, P.3
  • 14
    • 0021137420 scopus 로고
    • Idazoxan (RX 781094) selectively antagonizes alpha 2-adrenoceptors on rat central neurons
    • Freedman J.E., and Aghajanian G.K. Idazoxan (RX 781094) selectively antagonizes alpha 2-adrenoceptors on rat central neurons. Eur. J. Pharmacol. 105 (1984) 265-272
    • (1984) Eur. J. Pharmacol. , vol.105 , pp. 265-272
    • Freedman, J.E.1    Aghajanian, G.K.2
  • 15
    • 0028025252 scopus 로고
    • Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain
    • Garris P.A., Ciolkowski E.L., Pastore P., and Wightman R.M. Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain. J. Neurosci. 14 (1994) 6084-6093
    • (1994) J. Neurosci. , vol.14 , pp. 6084-6093
    • Garris, P.A.1    Ciolkowski, E.L.2    Pastore, P.3    Wightman, R.M.4
  • 16
    • 0342748363 scopus 로고    scopus 로고
    • Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons
    • Gartside S.E., Hajos-Korcsok E., Bagdy E., Harsing Jr. L.G., Sharp T., and Hajos M. Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience 98 (2000) 295-300
    • (2000) Neuroscience , vol.98 , pp. 295-300
    • Gartside, S.E.1    Hajos-Korcsok, E.2    Bagdy, E.3    Harsing Jr., L.G.4    Sharp, T.5    Hajos, M.6
  • 17
    • 76249084105 scopus 로고    scopus 로고
    • Ghanbari, R., El Mansari, M., Blier, P., in press. Electrophysiological effects of the co-administration of escitalopram and bupropion on rat serotonin and norepinephrine neurons. J. Psychopharmacol. doi:10.1177/0269881108095714.
    • Ghanbari, R., El Mansari, M., Blier, P., in press. Electrophysiological effects of the co-administration of escitalopram and bupropion on rat serotonin and norepinephrine neurons. J. Psychopharmacol. doi:10.1177/0269881108095714.
  • 18
    • 0023863123 scopus 로고
    • Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry
    • Gonon F.G. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience 24 (1988) 9-28
    • (1988) Neuroscience , vol.24 , pp. 9-28
    • Gonon, F.G.1
  • 19
    • 0020558538 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons
    • Grace A.A., and Bunney B.S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. Neuroscience 10 (1983) 301-348
    • (1983) Neuroscience , vol.10 , pp. 301-348
    • Grace, A.A.1    Bunney, B.S.2
  • 20
    • 0021718376 scopus 로고
    • The control of firing pattern in nigral dopamine neurons: burst firing
    • Grace A.A., and Bunney B.S. The control of firing pattern in nigral dopamine neurons: burst firing. J. Neurosci. 4 (1984) 2877-2890
    • (1984) J. Neurosci. , vol.4 , pp. 2877-2890
    • Grace, A.A.1    Bunney, B.S.2
  • 21
    • 46449102689 scopus 로고    scopus 로고
    • Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions
    • Guiard B.P., El Mansari M., Merali Z., and Blier P. Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. Int. J. Neuropsychopharmacol. 11 (2008) 625-639
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , pp. 625-639
    • Guiard, B.P.1    El Mansari, M.2    Merali, Z.3    Blier, P.4
  • 22
    • 0033623208 scopus 로고    scopus 로고
    • Effects of sustained (+/-)pindolol administration on serotonin neurotransmission in rats
    • Haddjeri N., and Blier P. Effects of sustained (+/-)pindolol administration on serotonin neurotransmission in rats. J. Psychiatry Neurosci. 25 (2000) 378-388
    • (2000) J. Psychiatry Neurosci. , vol.25 , pp. 378-388
    • Haddjeri, N.1    Blier, P.2
  • 23
    • 0030902677 scopus 로고    scopus 로고
    • Modulation of the firing activity of noradrenergic neurones in the rat locus coeruleus by the 5-hydroxtryptamine system
    • Haddjeri N., de Montigny C., and Blier P. Modulation of the firing activity of noradrenergic neurones in the rat locus coeruleus by the 5-hydroxtryptamine system. Br. J. Pharmacol. 120 (1997) 865-875
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 865-875
    • Haddjeri, N.1    de Montigny, C.2    Blier, P.3
  • 24
    • 0033135315 scopus 로고    scopus 로고
    • Modulation of the firing activity of rat serotonin and noradrenaline neurons by (+/-)pindolol
    • Haddjeri N., de Montigny C., and Blier P. Modulation of the firing activity of rat serotonin and noradrenaline neurons by (+/-)pindolol. Biol. Psychiatry 45 (1999) 1163-1169
    • (1999) Biol. Psychiatry , vol.45 , pp. 1163-1169
    • Haddjeri, N.1    de Montigny, C.2    Blier, P.3
  • 25
    • 5044233152 scopus 로고    scopus 로고
    • Electrophysiological evidence for the tonic activation of 5-HT(1A) autoreceptors in the rat dorsal raphe nucleus
    • Haddjeri N., Lavoie N., and Blier P. Electrophysiological evidence for the tonic activation of 5-HT(1A) autoreceptors in the rat dorsal raphe nucleus. Neuropsychopharmacology 29 (2004) 1800-1806
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1800-1806
    • Haddjeri, N.1    Lavoie, N.2    Blier, P.3
  • 26
    • 0030592690 scopus 로고    scopus 로고
    • Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation
    • Hajos M., and Sharp T. Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation. Brain Res. 740 (1996) 162-168
    • (1996) Brain Res. , vol.740 , pp. 162-168
    • Hajos, M.1    Sharp, T.2
  • 27
    • 0034696902 scopus 로고    scopus 로고
    • Effect of acute treatment with YM992 on extracellular norepinephrine levels in the rat frontal cortex
    • Hatanaka K., Yatsugi S., and Yamaguchi T. Effect of acute treatment with YM992 on extracellular norepinephrine levels in the rat frontal cortex. Eur. J. Pharmacol. 395 (2000) 31-36
    • (2000) Eur. J. Pharmacol. , vol.395 , pp. 31-36
    • Hatanaka, K.1    Yatsugi, S.2    Yamaguchi, T.3
  • 28
    • 0026516484 scopus 로고
    • Influence of impulse pattern on noradrenaline release from sympathetic nerves in cerebral and some peripheral vessels
    • Hardebo J.E. Influence of impulse pattern on noradrenaline release from sympathetic nerves in cerebral and some peripheral vessels. Acta. Physiol. Scand. 144 (1992) 333-339
    • (1992) Acta. Physiol. Scand. , vol.144 , pp. 333-339
    • Hardebo, J.E.1
  • 29
    • 0031464026 scopus 로고    scopus 로고
    • Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine
    • Hertel P., Nomikos G.G., and Svensson T.H. Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine. Br. J. Pharmacol. 122 (1997) 1639-1646
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1639-1646
    • Hertel, P.1    Nomikos, G.G.2    Svensson, T.H.3
  • 30
    • 53949102049 scopus 로고    scopus 로고
    • Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus
    • Huang M., Li Z., Dai J., Shahid M., Wong E.H., and Meltzer H.Y. Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus. Neuropsychopharmacology 33 (2008) 2934-2945
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2934-2945
    • Huang, M.1    Li, Z.2    Dai, J.3    Shahid, M.4    Wong, E.H.5    Meltzer, H.Y.6
  • 31
    • 0035096016 scopus 로고    scopus 로고
    • 5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release
    • Ichikawa J., Ishii H., Bonaccorso S., Fowler W.L., O'Laughlin I.A., and Meltzer H.Y. 5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release. J. Neurochem. 76 (2001) 1521-1531
    • (2001) J. Neurochem. , vol.76 , pp. 1521-1531
    • Ichikawa, J.1    Ishii, H.2    Bonaccorso, S.3    Fowler, W.L.4    O'Laughlin, I.A.5    Meltzer, H.Y.6
  • 32
    • 0037195552 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism
    • Ichikawa J., Li Z., Dai J., and Meltzer H.Y. Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism. Brain Res. 956 (2002) 349-357
    • (2002) Brain Res. , vol.956 , pp. 349-357
    • Ichikawa, J.1    Li, Z.2    Dai, J.3    Meltzer, H.Y.4
  • 33
    • 0001192938 scopus 로고
    • Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing
    • Kandel E.R., and Spencer W.A. Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing. J. Neurophysiol. 24 (1961) 243-259
    • (1961) J. Neurophysiol. , vol.24 , pp. 243-259
    • Kandel, E.R.1    Spencer, W.A.2
  • 34
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane J., Honigfeld G., Singer J., and Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch. Gen. Psychiatry 45 (1988) 789-796
    • (1988) Arch. Gen. Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 35
    • 1542776092 scopus 로고    scopus 로고
    • The expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders. Introduction: methods, commentary, and summary
    • Kane J.M., Leucht S., Carpenter D., and Docherty J.P. The expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders. Introduction: methods, commentary, and summary. J. Clin. Psychiatry 64 suppl 12 (2003) 5-19
    • (2003) J. Clin. Psychiatry , vol.64 , Issue.SUPPL. 12 , pp. 5-19
    • Kane, J.M.1    Leucht, S.2    Carpenter, D.3    Docherty, J.P.4
  • 36
    • 0345690100 scopus 로고    scopus 로고
    • Half a century of antipsychotics and still a central role for dopamine D2 receptors
    • Kapur S., and Mamo D. Half a century of antipsychotics and still a central role for dopamine D2 receptors. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 1081-1090
    • (2003) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.27 , pp. 1081-1090
    • Kapur, S.1    Mamo, D.2
  • 37
    • 34548009344 scopus 로고    scopus 로고
    • Long-term administration of citalopram reduces basal and stress-induced extracellular noradrenaline levels in rat brain
    • Kawahara Y., Kawahara H., Kaneko F., and Tanaka M. Long-term administration of citalopram reduces basal and stress-induced extracellular noradrenaline levels in rat brain. Psychopharmacology (Berl) 194 (2007) 73-81
    • (2007) Psychopharmacology (Berl) , vol.194 , pp. 73-81
    • Kawahara, Y.1    Kawahara, H.2    Kaneko, F.3    Tanaka, M.4
  • 38
    • 0029949349 scopus 로고    scopus 로고
    • Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine
    • Litman R.E., Su T.P., Potter W.Z., Hong W.W., and Pickar D. Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine. Br. J. Psychiatry 168 (1996) 571-579
    • (1996) Br. J. Psychiatry , vol.168 , pp. 571-579
    • Litman, R.E.1    Su, T.P.2    Potter, W.Z.3    Hong, W.W.4    Pickar, D.5
  • 39
    • 24144474010 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of quetiapine in bipolar depression
    • McFadden W., Calabrese J.R., and McCoy R. Double-blind, placebo-controlled study of quetiapine in bipolar depression. Int. J. Psychopharmacol. 7 suppl 1 (2004) S330
    • (2004) Int. J. Psychopharmacol. , vol.7 , Issue.SUPPL. 1
    • McFadden, W.1    Calabrese, J.R.2    McCoy, R.3
  • 41
    • 0002629884 scopus 로고
    • Atypical antipsychotic drugs
    • bloom F.E., and Kupfer D.J. (Eds), Raven Press, New York
    • Meltzer H.Y. Atypical antipsychotic drugs. In: bloom F.E., and Kupfer D.J. (Eds). Psychopharmacology: The fourth generation of progress (1995), Raven Press, New York 1277-1286
    • (1995) Psychopharmacology: The fourth generation of progress , pp. 1277-1286
    • Meltzer, H.Y.1
  • 42
    • 0027367344 scopus 로고
    • A 24-week study of 20 mg citalopram, 40 mg citalopram, and placebo in the prevention of relapse of major depression
    • Montgomery S.A., Rasmussen J.G., and Tanghoj P. A 24-week study of 20 mg citalopram, 40 mg citalopram, and placebo in the prevention of relapse of major depression. Int. Clin. Psychopharmacol. 8 (1993) 181-188
    • (1993) Int. Clin. Psychopharmacol. , vol.8 , pp. 181-188
    • Montgomery, S.A.1    Rasmussen, J.G.2    Tanghoj, P.3
  • 43
    • 29344438594 scopus 로고    scopus 로고
    • Use of atypical antipsychotics in refractory depression and anxiety
    • Nemeroff C.B. Use of atypical antipsychotics in refractory depression and anxiety. J. Clin. Psychiatry 66 suppl 8 (2005) 13-21
    • (2005) J. Clin. Psychiatry , vol.66 , Issue.SUPPL. 8 , pp. 13-21
    • Nemeroff, C.B.1
  • 44
    • 0030063466 scopus 로고    scopus 로고
    • Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors
    • Newman-Tancredi A., Chaput C., Verriele L., and Millan M.J. Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors. Neuropharmacology 35 (1996) 119-121
    • (1996) Neuropharmacology , vol.35 , pp. 119-121
    • Newman-Tancredi, A.1    Chaput, C.2    Verriele, L.3    Millan, M.J.4
  • 47
    • 0026772116 scopus 로고
    • Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine
    • Pickar D., Owen R.R., Litman R.E., Konicki E., Gutierrez R., and Rapaport M.H. Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. Arch. Gen. Psychiatry 49 (1992) 345-353
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 345-353
    • Pickar, D.1    Owen, R.R.2    Litman, R.E.3    Konicki, E.4    Gutierrez, R.5    Rapaport, M.H.6
  • 48
    • 35948982974 scopus 로고    scopus 로고
    • Efficacy and tolerability of asenapine in acute schizophrenia: a placebo- and risperidone-controlled trial
    • Potkin S.G., Cohen M., and Panagides J. Efficacy and tolerability of asenapine in acute schizophrenia: a placebo- and risperidone-controlled trial. J. Clin. Psychiatry 68 (2007) 1492-1500
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 1492-1500
    • Potkin, S.G.1    Cohen, M.2    Panagides, J.3
  • 49
    • 0001797297 scopus 로고
    • Behavioral correlates and firing repertoires of neurons in the dorsal hippocampal formation and septum of unrestrained rats
    • Isaacson L.R. (Ed), Plenum Press, New York
    • Ranck J.B. Behavioral correlates and firing repertoires of neurons in the dorsal hippocampal formation and septum of unrestrained rats. In: Isaacson L.R. (Ed). The hippocampus (1975), Plenum Press, New York 207-244
    • (1975) The hippocampus , pp. 207-244
    • Ranck, J.B.1
  • 50
    • 0030694503 scopus 로고    scopus 로고
    • Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation
    • Rollema H., Lu Y., Schmidt A.W., and Zorn S.H. Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Eur. J. Pharmacol. 338 (1997) R3-5
    • (1997) Eur. J. Pharmacol. , vol.338
    • Rollema, H.1    Lu, Y.2    Schmidt, A.W.3    Zorn, S.H.4
  • 52
    • 43049146626 scopus 로고    scopus 로고
    • Asenapine: a novel psychopharmacologic agent with a unique human receptor signature
    • (Electronic Publication ahead of print)
    • Shahid M., Walker G.B., Zorn S.H., and Wong E.H. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J. Psychopharmacol. (2008) (Electronic Publication ahead of print)
    • (2008) J. Psychopharmacol.
    • Shahid, M.1    Walker, G.B.2    Zorn, S.H.3    Wong, E.H.4
  • 53
    • 27544485778 scopus 로고    scopus 로고
    • Aripiprazole augmentation of antidepressants for the treatment of partially responding and nonresponding patients with major depressive disorder
    • Simon J.S., and Nemeroff C.B. Aripiprazole augmentation of antidepressants for the treatment of partially responding and nonresponding patients with major depressive disorder. J. Clin. Psychiatry 66 (2005) 1216-1220
    • (2005) J. Clin. Psychiatry , vol.66 , pp. 1216-1220
    • Simon, J.S.1    Nemeroff, C.B.2
  • 54
    • 0032845187 scopus 로고    scopus 로고
    • Comparison of the novel antipsychotic ziprazidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-HT1A receptor activation
    • Sprouse J.S., Reynolds L.S., Braselton J.P., Rollema H., and Zorn S.H. Comparison of the novel antipsychotic ziprazidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-HT1A receptor activation. Neuropsychopharmacology 21 (1999) 622-631
    • (1999) Neuropsychopharmacology , vol.21 , pp. 622-631
    • Sprouse, J.S.1    Reynolds, L.S.2    Braselton, J.P.3    Rollema, H.4    Zorn, S.H.5
  • 55
    • 0036720922 scopus 로고    scopus 로고
    • Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons
    • Szabo S.T., and Blier P. Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons. J. Pharmacol. Exp. Ther. 302 (2002) 983-991
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 983-991
    • Szabo, S.T.1    Blier, P.2
  • 56
    • 0033020993 scopus 로고    scopus 로고
    • Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers
    • Szabo S.T., de Montigny C., and Blier P. Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers. Br. J. Pharmacol. 126 (1999) 568-571
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 568-571
    • Szabo, S.T.1    de Montigny, C.2    Blier, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.