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Volumn 877, Issue 5-6, 2009, Pages 477-481
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Determination of asiatic acid in beagle dog plasma after oral administration of Centella asiatica extract by precolumn derivatization RP-HPLC
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Author keywords
Asiatic acid; Beagle dog; Centella asiatica extract; Pharmacokinetics; Precolumn derivatization HPLC
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Indexed keywords
ACIDS;
CHEMICAL REACTIONS;
CHROMATOGRAPHIC ANALYSIS;
DICHLOROMETHANE;
HEXANE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIQUID CHROMATOGRAPHY;
METHANOL;
PHARMACOKINETICS;
PINCH EFFECT;
PLASMAS;
2 PROPANOLS;
ASIATIC ACID;
BEAGLE DOG;
BEAGLE DOGS;
CALIBRATION CURVES;
CENTELLA ASIATICA EXTRACT;
CHROMATOGRAPHIC SEPARATIONS;
CONCENTRATION OF;
DOG PLASMAS;
EXTRACTION RECOVERIES;
GRADIENT ELUTIONS;
LOWER LIMIT OF QUANTIFICATIONS;
N HEXANES;
ORAL ADMINISTRATIONS;
PHARMACOKINETIC PARAMETERS;
PHARMACOKINETIC STUDIES;
PLASMA SAMPLES;
PRECOLUMN DERIVATIZATION HPLC;
QUANTITATIVE DETERMINATIONS;
REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;
RP-HPLC;
URSOLIC ACIDS;
UV WAVELENGTHS;
WATER-METHANOL SYSTEMS;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
ASIATIC ACID;
CENTELLA ASIATICA EXTRACT;
DICHLOROMETHANE;
N HEXANE DICHLOROMETHANE 2 PROPANOL;
PROPANOL;
TOLUIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
URSOLIC ACID;
ACCURACY;
AREA UNDER THE CURVE;
ARTICLE;
CENTELLA ASIATICA;
DERIVATIZATION;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG HYDROLYSIS;
DRUG ISOLATION;
DRUG STRUCTURE;
ELUTION;
EXPERIMENTAL DOG;
PRIORITY JOURNAL;
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
SINGLE DRUG DOSE;
ULTRAVIOLET SPECTROSCOPY;
ADMINISTRATION, ORAL;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DOGS;
DRUG STABILITY;
HYDROLYSIS;
REPRODUCIBILITY OF RESULTS;
TIME FACTORS;
TRITERPENES;
CANIS FAMILIARIS;
CENTELLA ASIATICA;
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EID: 58949087352
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2008.11.045 Document Type: Article |
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Times cited : (31)
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References (11)
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