Increased mast cell density in haemorrhoid venous blood vessels suggests a role in pathogenesis

Singapore Medical Journal

Volumn 49, Issue 12, 2008, Pages 977-979

  Taweevisit, Mana ^a   Wisadeopas, N ^a   Phumsuk, U ^a   Thorner, P S ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Anorectal tissue; Cytokines; Haemorrhoid pathophysiology; Haemorrhoids; Inflammatory mediators; Mast cells

Indexed keywords

ADULT; ARTICLE; BLOOD VESSEL; CELL DENSITY; CLINICAL ARTICLE; CONTROLLED STUDY; HEMORRHOID; HUMAN; HUMAN TISSUE; MAST CELL; PATHOGENESIS; PATHOPHYSIOLOGY; RETROSPECTIVE STUDY; STAINING;

ANAL CANAL; HEMORRHOIDS; HUMANS; MAST CELLS; MIDDLE AGED; VEINS;

EID: 58849158281     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Nisar P, Scholefield J. Managing haemorrhoids. BMJ 2003; 327:847-51.
2. Zuber T. Hemorrhoidectomy for thrombosed external hemorrhoids. Am Fam Physician 2002; 65:1629-32.
3. Schussman L, Lutz L. Outpatient management of hemorrhoids. Prim Care 1986; 13:527-41.
4. Johannsson H, Graf W, Pahlman L. Bowel habits in hemorrhoid patients and normal subjects. Am J Gastroenterol 2005; 100:401-6.
5. Sun W, Read N, Shorthouse A. Hypertensive anal cushions as a cause of the high anal canal pressure in patients with haemorrhoids. Br J Surg 1990; 77:458-62.
6. Ibaraki T, Muramatsu M, Takai S, et al. The relationship of tryptase- and chymase-positive mast cells to angiogenesis in stage I non-small cell lung cancer. Eur J Cardiothorac Surg 2005; 28:617-21.
7. Marshall J, Jawdat D. Mast cells in innate immunity. J Allergy Clin Immunol 2004; 114:21-7.
8. Haviarova Z, Weismann P, Pavlikova D, et al. Mast cell infiltration in the wall of varicose veins. Acta Histochem 2002; 104:357-60.
9. Kinnula V, Hodgson U, Lakari E, et al. Extracellular superoxide dismutase has a highly specific localization in idiopathic pulmonary fibrosis/usual interstitial pneumonia. Histopathology 2006; 49:66-74.
10. Qu Z, Liebler J, Powers M, et al. Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma. Am J Pathol 1995; 147:564-73.
11. Qu Z, Kayton R, Ahmadi P, et al. Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granules. Morphological evidence for bFGF release through degranulation. J Histochem Cytochem 1998; 46:119-28.
12. Glowacki J, Mulliken J. Mast cells in hemangiomas and vascular malformations. Pediatrics 1982; 70:48-51.
13. Pasyk K, Cherry G, Grabb W, Sasaki G. Quantitative evaluation of mast cells in cellularly dynamic and adynamic vascular malformations. Plast Reconstr Surg 1984; 73:69-77.
14. Krishnaswamy G, Ajitawi O, Chi D. The human mast cell: an overview. Methods Mol Biol 2006; 315:13-34.
15. Kitaura-Inenaga K, Hara M, Higuchi K, et al. Gene expression of cardiac mast cell chymase and tryptase in a murine model of heart failure caused by viral myocarditis. Circ J 2003; 67:881-4.