BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 4, 2009, Pages 753-758

  Bacolod, Manny D ^a,b   Fehdrau, Randy ^a   Johnson, Stewart P ^a   Bullock, Nancy S ^a   Bigner, Darell D ^a   Colvin, Michael ^a   Friedman, Henry S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

BCNU; Brain tumor; Cancer drug resistance; Carmustine; Medulloblastoma; Metallothionein

Indexed keywords

CADMIUM; CARMUSTINE; GLUTATHIONE; METALLOTHIONEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; ZINC;

ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CONTROLLED STUDY; DRUG DECOMPOSITION; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

CARMUSTINE; CEREBELLAR NEOPLASMS; DRUG RESISTANCE, NEOPLASM; HUMANS; MEDULLOBLASTOMA; METALLOTHIONEIN; TUMOR CELLS, CULTURED;

EID: 58849156422     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0792-9     Document Type: Article

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