The effects of liberal versus restrictive transfusion thresholds on ambulation after hip fracture surgery

Transfusion

Volumn 49, Issue 2, 2009, Pages 227-234

  Foss, Nicolai B ^a   Kristensen, Morten Tange ^b   Jensen, Pia Søe ^b   Palm, Henrik ^b   Krasheninnikoff, Michael ^b   Kehlet, Henrik ^b  

^a HVIDOVRE HOSPITAL   (Denmark)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CEFUROXIME; ENOXAPARIN; HEMOGLOBIN;

AGED; ANEMIA; ARTICLE; BLOOD TRANSFUSION; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HIP FRACTURE; HIP SURGERY; HOSPITALIZATION; HUMAN; HYPOVOLEMIA; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; PATIENT MOBILITY; PERIOPERATIVE PERIOD; POSTOPERATIVE INFECTION; POSTOPERATIVE THROMBOSIS; RANDOMIZED CONTROLLED TRIAL; REHABILITATION CARE;

AGED; AGED, 80 AND OVER; BLOOD TRANSFUSION; DENMARK; FEMALE; GUIDELINES AS TOPIC; HEMOGLOBINS; HIP FRACTURES; HOSPITALIZATION; HUMANS; LENGTH OF STAY; MALE; PERIOPERATIVE CARE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; WALKING;

EID: 58849155196     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2008.01967.x     Document Type: Article

References (30)

1. Foss NB, Kehlet H. Hidden blood loss after hip fracture surgery. J Bone Joint Surg Br 2006 88 : 1053 9.
2. Marval PD, Hardman JG. Perioperative blood loss and transfusion requirements in patients with fractured neck of femur. Eur J Anaesthesiol 2004 21 : 412 4.
3. Carson JL, Duff A, Poses RM, Berlin JA, Spence RK, Trout R, Noveck H, Strom BL. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet 1996 348 : 1055 60.
4. Wu WC, Schifftner TL, Henderson WG, Eaton CB, Poses RM, Uttley G, Sharma SC, Vezeridis M, Khuri SF, Friedmann PD. Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA 2007 297 : 2481 8.
5. Carson JL, Terrin ML, Magaziner J. Anemia and postoperative rehabilitation. Can J Anaesth 2003 50 : S60 4.
6. Carson JL, Noveck H, Berlin JA, Gould SA. Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion. Transfusion 2002 42 : 812 8.
7. Carson JL, Duff A, Berlin JA, Lawrence VA, Poses RM, Huber EC, O'Hara DA, Noveck H, Strom BL. Perioperative blood transfusion and postoperative mortality. JAMA 1998 279 : 199 205.
8. Halm EA, Wang JJ, Boockvar K, Penrod J, Silberzweig SB, Magaziner J, Koval KJ, Siu AL. The effect of perioperative anemia on clinical and functional outcomes in patients with hip fracture. J Orthop Trauma 2004 18 : 369 74.
9. Lawrence VA, Silverstein JH, Cornell JE, Pederson T, Noveck H, Carson JL. Higher Hb level is associated with better early functional recovery after hip fracture repair. Transfusion 2003 43 : 1717 22.
10. Foss NB, Kristensen MT, Kehlet H. Anaemia impedes functional mobility after hip fracture surgery. Age Ageing 2008 37 : 173 8.
11. Carson JL, Terrin ML, Barton FB, Aaron R, Greenburg AG, Heck DA, Magaziner J, Merlino FE, Bunce G, McClelland B, Duff A, Noveck H. A pilot randomized trial comparing symptomatic vs. haemoglobin-level-driven red blood cell transfusion following hip fracture. Transfusion 1998 38 : 522 9.
12. Whitley E, Ball J. Statistical review 4: sample size calculations. Crit Care 2002 6 : 335 41.
13. Foss NB, Kristensen MT, Kristensen BB, Jensen PS, Kehlet H. Effect of postoperative epidural analgesia on rehabilitation and pain after hip fracture surgery: a randomized, double-blind, placebo-controlled trial. Anesthesiology 2005 102 : 1197 204.
14. Quereshi KN, Hodkinson HM. Evaluation of a ten-question mental test in the institutionalised elderly. Age Ageing 1974 3 : 152 7.
15. Parker MJ, Palmer CR. A new mobility score for predicting mortality after hip fracture. J Bone Joint Surg Br 1993 75 : 797 8.
16. Foss NB, Kristensen MT, Kehlet H. Prediction of postoperative rehabilitation and mortality after hip fracture: the cumulated ambulation score. Clin Rehabil 2006 20 : 701 8.
17. Halm EA, Wang JJ, Boockvar K, Penrod J, Silberzweig SB, Magaziner J, Koval KJ, Siu AL. Effects of blood transfusion on clinical and functional outcomes in patients with hip fracture. Transfusion 2003 43 : 1358 65.
18. Kehlet H, Dahl JB. Anaesthesia, surgery and challenges in postoperative recovery. Lancet 2003 362 : 1921 8.
19. Morrison RS, Magaziner J, McLaughlin MA, Orosz G, Silberzweig SB, Koval KJ, Siu AL. The impact of post-operative pain on outcomes following hip fracture. Pain 2003 103 : 303 11.
20. Foss NB, Kristensen MT, Palm H, Kehlet H. Postoperative pain after hip fracture surgery is procedure specific. Br J Anaesth 2008, in press.
21. Palm H, Jacobsen S, Sonne-Holm S, Gebuhr P. Integrity of the lateral femoral wall in intertrochanteric hip fractures: an important predictor of a reoperation. J Bone Joint Surg Am 2007 89 : 470 5.
22. Foss NB, Kehlet H. Mortality in hip fracture patients after admitted during weekends and holidays. Br J Anaesth 2006 96 : 450 4.
23. Lu-Yao GL, Baron JA, Barrett JA, Fisher ES. Treatment and survival among elderly Americans with hip fracture: a population based study. Am J Public Health 1994 84 : 1287 91.
24. Matot I, Oppenheim-Eden A, Ratrot R, Baranova J, Davidson E, Eylon S, Peyser A, Liebergall M. Preoperative cardiac events in elderly patients with hip fracture randomized to epidural or conventional analgesia. Anesthesiology 2003 98 : 156 63.
25. Scheinin H, Virtanen T, Kentala E, Uotila P, Laitio T, Hartiala J, Heikkila H, Sarioloa-Heinonen K, Pullisaar O, Yli-Mayry S, Jalonen J. Epidural infusion of bupivacaine and fentanyl reduces perioperative myocardial ischaemia in elderly patients with hip fracture - a randomized controlled trial. Acta Anaesthesiol Scand 2000 44 : 1061 70.
26. Freudenberger RS, Carson JL. Is there an optimal hemoglobin value in the cardiac intensive care unit? Curr Opin Crit Care 2003 9 : 356 61.
27. Nielsen HJ. Detrimental effects of perioperative blood transfusion. Br J Surg 1995 82 : 582 7.
28. Carson JL, Altman DG, Duff A, Noveck H, Weinstein MP, Sonnenberg FA, Hudson JI, Provenzano G. Risk of bacterial infection associated with allogenic blood transfusion among patients undergoing hip fracture repair. Transfusion 1999 39 : 694 700.
29. Johnston P, Wynn-Jones H, Chakravarty D, Boyle A, Parker MJ. Is perioperative blood transfusion a risk factor for mortality or infection after hip fracture? J Orthop Trauma 2006 20 : 675 9.
30. Merrer J, Girou E, Lortat-Jacob A, Montravers P, Lucet JC. Surgical site infection after surgery to repair femoral neck fracture: a French multicenter retrospective study. Infect Control Hosp Epidemiol 2007 28 : 1169 74.