Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension

Journal of Hypertension

Volumn 27, Issue 1, 2009, Pages 181-189

  Maekawa, Ai ^a   Kakizoe, Yutaka ^a   Miyoshi, Taku ^a   Wakida, Naoki ^a   Ko, Takehiro ^a   Shiraishi, Naoki ^a   Adachi, Masataka ^a   Tomita, Kimio ^a   Kitamura, Kenichiro ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Epithelial sodium channel; Prostasin; Renal injury; Salt sensitive hypertension; Serine protease inhibitor

Indexed keywords

4 (4 GUANIDINOBENZOYLOXY)PHENYLACETIC ACID; CAMOSTAT MESILATE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CREATININE; EPITHELIAL SODIUM CHANNEL; NEPHRIN; POTASSIUM; PROSTASIN; PROTEINASE; SODIUM; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1; 4-(4-GUANIDINOBENZOYLOXY)PHENYLACETIC ACID; ALDOSTERONE; ANTIHYPERTENSIVE AGENT; DRUG DERIVATIVE; GABEXATE; GUANIDINE DERIVATIVE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DAHL SALT SENSITIVE RAT; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; GENE SILENCING; HYPERTENSION; IN VITRO STUDY; KIDNEY; KIDNEY COLLECTING TUBULE; KIDNEY INJURY; NONHUMAN; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; SALT INTAKE; SODIUM TRANSPORT; SODIUM URINE LEVEL; ANIMAL; BLOOD; CELL CULTURE; GENETICS; MOUSE; PATHOLOGY;

ALDOSTERONE; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CELLS, CULTURED; GABEXATE; GUANIDINES; HYPERTENSION; KIDNEY; MICE; RATS; RATS, INBRED DAHL; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS;

EID: 58849147112     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328317a762     Document Type: Article

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