-
1
-
-
39549093148
-
General cardiovascular risk profile for use in primary care: The Framingham Heart Study
-
Feb 12;
-
D'Agostino Sr RB, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008 Feb 12; 117 (6): 743-53
-
(2008)
Circulation
, vol.117
, Issue.6
, pp. 743-753
-
-
D'Agostino Sr, R.B.1
Vasan, R.S.2
Pencina, M.J.3
-
2
-
-
0033953535
-
Risk stratification in hypertension: New insights from the Framingham Study
-
Jan;
-
Kannel WB. Risk stratification in hypertension: new insights from the Framingham Study. Am J Hypertens 2000 Jan; 13 (1 Pt 2): 3S-10S
-
(2000)
Am J Hypertens
, vol.13
, Issue.1 PART 2
-
-
Kannel, W.B.1
-
3
-
-
0038047699
-
Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States
-
May 14;
-
Wolf-Maier K, Cooper RS, Banegas JR, et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA 2003 May 14; 289 (18): 2363-9
-
(2003)
JAMA
, vol.289
, Issue.18
, pp. 2363-2369
-
-
Wolf-Maier, K.1
Cooper, R.S.2
Banegas, J.R.3
-
4
-
-
34547841317
-
Essential hypertension
-
Aug 18;
-
Messerli FH, Williams B, Ritz E. Essential hypertension. Lancet 2007 Aug 18; 370 (9587): 591-603
-
(2007)
Lancet
, vol.370
, Issue.9587
, pp. 591-603
-
-
Messerli, F.H.1
Williams, B.2
Ritz, E.3
-
5
-
-
34547841331
-
Hypertension: Uncontrolled and conquering the world
-
Aug 18;
-
Hypertension: uncontrolled and conquering the world. Lancet 2007 Aug 18; 370 (9587): 539
-
(2007)
Lancet
, vol.370
, Issue.9587
, pp. 539
-
-
-
6
-
-
33847096347
-
Blood pressure parameters and risk of fatal stroke, NHANES II mortality study
-
Mar;
-
Brown DW, Giles WH, Greenlund KJ. Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. Am J Hypertens 2007 Mar; 20 (3): 338-41
-
(2007)
Am J Hypertens
, vol.20
, Issue.3
, pp. 338-341
-
-
Brown, D.W.1
Giles, W.H.2
Greenlund, K.J.3
-
7
-
-
40949133247
-
Treatment potential for cholesterol management in patients with coronary heart disease in 15 European countries: Findings from the EUROASPIRE II survey
-
Apr;
-
Kotseva K, Stagmo M, De Bacquer D, et al. Treatment potential for cholesterol management in patients with coronary heart disease in 15 European countries: findings from the EUROASPIRE II survey. Atherosclerosis 2008 Apr; 197 (2): 710-7
-
(2008)
Atherosclerosis
, vol.197
, Issue.2
, pp. 710-717
-
-
Kotseva, K.1
Stagmo, M.2
De Bacquer, D.3
-
8
-
-
4143134423
-
Risk factor management in diabetic and non-diabetic patients with coronary heart disease: Findings from the EUROAS-PIRE I AND II surveys
-
Jul;
-
Pyorala K, Lehto S, De Bacquer D, et al. Risk factor management in diabetic and non-diabetic patients with coronary heart disease: findings from the EUROAS-PIRE I AND II surveys. Diabetologia 2004 Jul; 47 (7): 1257-65
-
(2004)
Diabetologia
, vol.47
, Issue.7
, pp. 1257-1265
-
-
Pyorala, K.1
Lehto, S.2
De Bacquer, D.3
-
9
-
-
12444263222
-
Blood pressure is insufficiently controlled in European patients with established coronary heart disease
-
Oct;
-
Boersma E, Keil U, De Bacquer D, et al. Blood pressure is insufficiently controlled in European patients with established coronary heart disease. J Hypertens 2003 Oct; 21 (10): 1831-40
-
(2003)
J Hypertens
, vol.21
, Issue.10
, pp. 1831-1840
-
-
Boersma, E.1
Keil, U.2
De Bacquer, D.3
-
10
-
-
34447314994
-
World Health Organization (WHO) and International Society of Hypertension (ISH) risk prediction charts: Assessment of cardiovascular risk for prevention and control of cardiovascular disease in low and middle-income countries
-
Aug;
-
Mendis S, Lindholm LH, Mancia G, et al. World Health Organization (WHO) and International Society of Hypertension (ISH) risk prediction charts: assessment of cardiovascular risk for prevention and control of cardiovascular disease in low and middle-income countries. J Hypertens 2007 Aug; 25 (8): 1578-82
-
(2007)
J Hypertens
, vol.25
, Issue.8
, pp. 1578-1582
-
-
Mendis, S.1
Lindholm, L.H.2
Mancia, G.3
-
11
-
-
53749091595
-
Long-term follow-up after tight control of blood pressure in type 2 diabetes
-
Oct 9;
-
Holman RR, Paul SK, Bethel MA, et al. Long-term follow-up after tight control of blood pressure in type 2 diabetes. N Engl J Med 2008 Oct 9; 359 (15): 1565-76
-
(2008)
N Engl J Med
, vol.359
, Issue.15
, pp. 1565-1576
-
-
Holman, R.R.1
Paul, S.K.2
Bethel, M.A.3
-
12
-
-
24644510705
-
Long-term effects of ramipril on cardiovascular events and on diabetes: Results of the HOPE study extension
-
Aug 30;
-
Bosch J, Lonn E, Pogue J, et al. Long-term effects of ramipril on cardiovascular events and on diabetes: results of the HOPE study extension. Circulation 2005 Aug 30; 112 (9): 1339-46
-
(2005)
Circulation
, vol.112
, Issue.9
, pp. 1339-1346
-
-
Bosch, J.1
Lonn, E.2
Pogue, J.3
-
13
-
-
33646181189
-
-
Ahn SA, Jong P, Yusuf S, et al. Early versus delayed enalapril in patients with left ventricular systolic dysfunction: impact on morbidity and mortality 15 years after the SOLVD trial. J Am Coll Cardiol 2006 May 2; 47 (9): 1904-5
-
Ahn SA, Jong P, Yusuf S, et al. Early versus delayed enalapril in patients with left ventricular systolic dysfunction: impact on morbidity and mortality 15 years after the SOLVD trial. J Am Coll Cardiol 2006 May 2; 47 (9): 1904-5
-
-
-
-
14
-
-
0032912752
-
Long-term survival in severe heart failure in patients treated with enalapril: Ten year follow-up of CONSENSUS I
-
Jan;
-
Swedberg K, Kjekshus J, Snapinn S. Long-term survival in severe heart failure in patients treated with enalapril: ten year follow-up of CONSENSUS I. Eur Heart J 1999 Jan; 20 (2): 136-9
-
(1999)
Eur Heart J
, vol.20
, Issue.2
, pp. 136-139
-
-
Swedberg, K.1
Kjekshus, J.2
Snapinn, S.3
-
15
-
-
49349109830
-
Development of heart failure in recent hypertension trials
-
Jul;
-
Tocci G, Sciarretta S, Volpe M. Development of heart failure in recent hypertension trials. J Hypertens 2008 Jul; 26 (7): 1477-86
-
(2008)
J Hypertens
, vol.26
, Issue.7
, pp. 1477-1486
-
-
Tocci, G.1
Sciarretta, S.2
Volpe, M.3
-
16
-
-
0345492460
-
A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial
-
Dec 3;
-
Pepine CJ, Handberg EM, Cooper-DeHoff RM, et al. A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. JAMA 2003 Dec 3; 290 (21): 2805-16
-
(2003)
JAMA
, vol.290
, Issue.21
, pp. 2805-2816
-
-
Pepine, C.J.1
Handberg, E.M.2
Cooper-DeHoff, R.M.3
-
17
-
-
0344373794
-
Major outcomes in high-risk hypertensive patients ran-domized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
-
ALLHAT Investigators, Dec 18;
-
ALLHAT Investigators. Major outcomes in high-risk hypertensive patients ran-domized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002 Dec 18; 288 (23): 2981-97
-
(2002)
JAMA
, vol.288
, Issue.23
, pp. 2981-2997
-
-
-
18
-
-
0029584472
-
Evaluating the benefits of an antihypertensive agent using trials based on event and organ damage: The Systolic Hypertension in the Elderly Long-term Lacidipine (SHELL) trial and the European Lacidipine Study on Atherosclerosis (ELSA)
-
Dec;
-
Zanchetti A. Evaluating the benefits of an antihypertensive agent using trials based on event and organ damage: the Systolic Hypertension in the Elderly Long-term Lacidipine (SHELL) trial and the European Lacidipine Study on Atherosclerosis (ELSA). J Hypertens Suppl 1995 Dec; 13 (4): S35-9
-
(1995)
J Hypertens Suppl
, vol.13
, Issue.4
-
-
Zanchetti, A.1
-
19
-
-
0034688194
-
Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
-
Jan 20;
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000 Jan 20; 342 (3): 145-53
-
(2000)
N Engl J Med
, vol.342
, Issue.3
, pp. 145-153
-
-
Yusuf, S.1
Sleight, P.2
Pogue, J.3
-
20
-
-
0035968623
-
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack
-
Group TPpaRSSPC, Sep 29;
-
Group TPpaRSSPC. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001 Sep 29; 358 (9287): 1033-41
-
(2001)
Lancet
, vol.358
, Issue.9287
, pp. 1033-1041
-
-
-
21
-
-
0042330455
-
Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: Randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study)
-
Sep 6;
-
Fox KM. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003 Sep 6; 362 (9386): 782-8
-
(2003)
Lancet
, vol.362
, Issue.9386
, pp. 782-788
-
-
Fox, K.M.1
-
22
-
-
19644400972
-
-
Braunwald E, Domanski MJ, Fowler SE, et al. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004 Nov 11; 351 (20): 2058-68
-
Braunwald E, Domanski MJ, Fowler SE, et al. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004 Nov 11; 351 (20): 2058-68
-
-
-
-
23
-
-
0037420492
-
Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
-
Apr 5;
-
Sever PS, Dahlof B, Poulter NR, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003 Apr 5; 361 (9364): 1149-58
-
(2003)
Lancet
, vol.361
, Issue.9364
, pp. 1149-1158
-
-
Sever, P.S.1
Dahlof, B.2
Poulter, N.R.3
-
24
-
-
0026785561
-
Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
-
The SOLVD Investigators, Sep 3;
-
The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 1992 Sep 3; 327 (10): 685-91
-
(1992)
N Engl J Med
, vol.327
, Issue.10
, pp. 685-691
-
-
-
25
-
-
0025913812
-
Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
-
The SOLVD Investigators, Aug 1;
-
The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991 Aug 1; 325 (5): 293-302
-
(1991)
N Engl J Med
, vol.325
, Issue.5
, pp. 293-302
-
-
-
26
-
-
34548420712
-
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
-
Sep 8;
-
Patel A, MacMahon S, Chalmers J, et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 2007 Sep 8; 370 (9590): 829-40
-
(2007)
Lancet
, vol.370
, Issue.9590
, pp. 829-840
-
-
Patel, A.1
MacMahon, S.2
Chalmers, J.3
-
27
-
-
0023266532
-
Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
-
The CONSENSUS Trial Study Group, Jun 4;
-
The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 1987 Jun 4; 316 (23): 1429-35
-
(1987)
N Engl J Med
, vol.316
, Issue.23
, pp. 1429-1435
-
-
-
28
-
-
42049107348
-
Telmisartan, ramipril, or both in patients at high risk for vascular events
-
Apr 10;
-
Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008 Apr 10; 358 (15): 1547-59
-
(2008)
N Engl J Med
, vol.358
, Issue.15
, pp. 1547-1559
-
-
Yusuf, S.1
Teo, K.K.2
Pogue, J.3
-
29
-
-
0037160969
-
Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
-
Mar 23;
-
Lindholm LH, Ibsen H, Dahlof B, et al. Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002 Mar 23; 359 (9311): 1004-10
-
(2002)
Lancet
, vol.359
, Issue.9311
, pp. 1004-1010
-
-
Lindholm, L.H.1
Ibsen, H.2
Dahlof, B.3
-
30
-
-
34247379373
-
Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): A randomised, open-label, blinded endpoint morbidity-mortality study
-
Apr 28;
-
Mochizuki S, Dahlof B, Shimizu M, et al. Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet 2007 Apr 28; 369 (9571): 1431-9
-
(2007)
Lancet
, vol.369
, Issue.9571
, pp. 1431-1439
-
-
Mochizuki, S.1
Dahlof, B.2
Shimizu, M.3
-
31
-
-
2942635317
-
-
Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004 Jun 19; 363 (9426): 2022-31
-
Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004 Jun 19; 363 (9426): 2022-31
-
-
-
-
32
-
-
0242490542
-
-
Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003 Nov 13; 349 (20): 1893-906
-
Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003 Nov 13; 349 (20): 1893-906
-
-
-
-
33
-
-
0035818884
-
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
-
Dec 6;
-
Cohn JN, Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 2001 Dec 6; 345 (23): 1667-75
-
(2001)
N Engl J Med
, vol.345
, Issue.23
, pp. 1667-1675
-
-
Cohn, J.N.1
Tognoni, G.2
-
34
-
-
0035922444
-
The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
-
Sep 20;
-
Parving HH, Lehnert H, Brochner-Mortensen J, et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001 Sep 20; 345 (12): 870-8
-
(2001)
N Engl J Med
, vol.345
, Issue.12
, pp. 870-878
-
-
Parving, H.H.1
Lehnert, H.2
Brochner-Mortensen, J.3
-
35
-
-
52249116778
-
Telmisartan to prevent recurrent stroke and cardiovascular events
-
Sep 18;
-
Yusuf S, Diener HC, Sacco RL, et al. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med 2008 Sep 18; 359 (12): 1225-37
-
(2008)
N Engl J Med
, vol.359
, Issue.12
, pp. 1225-1237
-
-
Yusuf, S.1
Diener, H.C.2
Sacco, R.L.3
-
36
-
-
53049109468
-
Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial
-
Sep 27;
-
Yusuf S, Teo K, Anderson C, et al., Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet. 2008 Sep 27; 372 (9644): 1174-83
-
(2008)
Lancet
, vol.372
, Issue.9644
, pp. 1174-1183
-
-
Yusuf, S.1
Teo, K.2
Anderson, C.3
-
37
-
-
20444427156
-
Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: Principal results of a prospective randomized controlled study (MOSES)
-
Jun;
-
Schrader J, Luders S, Kulschewski A, et al. Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 2005 Jun; 36 (6): 1218-26
-
(2005)
Stroke
, vol.36
, Issue.6
, pp. 1218-1226
-
-
Schrader, J.1
Luders, S.2
Kulschewski, A.3
-
38
-
-
34548383480
-
ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension
-
Sep;
-
Mancia G, De Backer G, Dominiczak A, et al. 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. J Hypertens 2007 Sep; 25 (9): 1751-62
-
(2007)
J Hypertens
, vol.25
, Issue.9
, pp. 1751-1762
-
-
Mancia, G.1
De Backer, G.2
Dominiczak, A.3
-
39
-
-
39449086771
-
Therapeutic implications of recent megatrials in hypertension: In favor of new drugs
-
Nov-Dec;
-
Volpe M, Tocci G. Therapeutic implications of recent megatrials in hypertension: in favor of new drugs. J Nephrol 2007 Nov-Dec; 20 Suppl. 12: S12-8
-
(2007)
J Nephrol
, vol.20
, Issue.SUPPL. 12
-
-
Volpe, M.1
Tocci, G.2
-
40
-
-
33645470860
-
Fewer mega-trials and more clinically oriented studies in hypertension research? The case of blocking the renin-angiotensin-aldosterone system
-
Apr;
-
Volpe M, Tocci G, Pagannone E. Fewer mega-trials and more clinically oriented studies in hypertension research? The case of blocking the renin-angiotensin-aldosterone system. J Am Soc Nephrol 2006 Apr; 17 (4 Suppl. 2): S36-43
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.4 SUPPL. 2
-
-
Volpe, M.1
Tocci, G.2
Pagannone, E.3
-
41
-
-
34250322546
-
Blood pressure control in Italy: Results of recent surveys on hypertension
-
Jul;
-
Volpe M, Tocci G, Trimarco B, et al. Blood pressure control in Italy: results of recent surveys on hypertension. J Hypertens 2007 Jul; 25 (7): 1491-8
-
(2007)
J Hypertens
, vol.25
, Issue.7
, pp. 1491-1498
-
-
Volpe, M.1
Tocci, G.2
Trimarco, B.3
-
42
-
-
0036668188
-
Systolic and diastolic blood pressure control in antihypertensive drug trials
-
Aug;
-
Mancia G, Grassi G. Systolic and diastolic blood pressure control in antihypertensive drug trials. J Hypertens 2002 Aug; 20 (8): 1461-4
-
(2002)
J Hypertens
, vol.20
, Issue.8
, pp. 1461-1464
-
-
Mancia, G.1
Grassi, G.2
-
43
-
-
34047231332
-
Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: Is oral renin inhibition the solution?
-
Apr;
-
Athyros VG, Mikhailidis DP, Kakafika AI, et al. Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution? Expert Opin Pharmacother 2007 Apr; 8 (5): 529-35
-
(2007)
Expert Opin Pharmacother
, vol.8
, Issue.5
, pp. 529-535
-
-
Athyros, V.G.1
Mikhailidis, D.P.2
Kakafika, A.I.3
-
44
-
-
58149391855
-
Renin receptor blockade: A better strategy for renal protection than renin-angiotensin system inhibition?
-
Oct;
-
Muller DN, Luft FC. Renin receptor blockade: a better strategy for renal protection than renin-angiotensin system inhibition? Curr Hypertens Rep 2008 Oct; 10 (5): 405-9
-
(2008)
Curr Hypertens Rep
, vol.10
, Issue.5
, pp. 405-409
-
-
Muller, D.N.1
Luft, F.C.2
-
45
-
-
33749985149
-
Oral renin inhibitors
-
Oct 21;
-
Staessen JA, Li Y, Richart T. Oral renin inhibitors. Lancet 2006 Oct 21; 368 (9545): 1449-56
-
(2006)
Lancet
, vol.368
, Issue.9545
, pp. 1449-1456
-
-
Staessen, J.A.1
Li, Y.2
Richart, T.3
-
46
-
-
0042738775
-
Angiotensin II AT2 receptor subtype: An uprising frontier in cardiovascular disease?
-
Aug;
-
Volpe M, Musumeci B, De Paolis P, et al. Angiotensin II AT2 receptor subtype: an uprising frontier in cardiovascular disease? J Hypertens 2003 Aug; 21 (8): 1429-43
-
(2003)
J Hypertens
, vol.21
, Issue.8
, pp. 1429-1443
-
-
Volpe, M.1
Musumeci, B.2
De Paolis, P.3
-
47
-
-
33845882230
-
The cardiovascular disease continuum validated: Clinical evidence of improved patient outcomes, part II: clinical trial evidence (acute coronary syndromes through renal disease) and future directions
-
Dec 19;
-
Dzau VJ, Antman EM, Black HR, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes, part II: clinical trial evidence (acute coronary syndromes through renal disease) and future directions. Circulation 2006 Dec 19; 114 (25): 2871-91
-
(2006)
Circulation
, vol.114
, Issue.25
, pp. 2871-2891
-
-
Dzau, V.J.1
Antman, E.M.2
Black, H.R.3
-
48
-
-
33845902544
-
The cardiovascular disease continuum validated: Clinical evidence of improved patient outcomes, part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)
-
Dec 19;
-
Dzau VJ, Antman EM, Black HR, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes, part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation 2006 Dec 19; 114 (25): 2850-70
-
(2006)
Circulation
, vol.114
, Issue.25
, pp. 2850-2870
-
-
Dzau, V.J.1
Antman, E.M.2
Black, H.R.3
-
49
-
-
18544369738
-
The cardiovascular continuum and renin-angiotensin-aldosterone system blockade
-
Apr;
-
Dzau V. The cardiovascular continuum and renin-angiotensin-aldosterone system blockade. J Hypertens Suppl 2005 Apr; 23 (1): S9-17
-
(2005)
J Hypertens Suppl
, vol.23
, Issue.1
-
-
Dzau, V.1
-
50
-
-
0029065156
-
Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke)
-
Jun;
-
Laragh JH. Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke). J Hum Hypertens 1995 Jun; 9 (6): 385-90
-
(1995)
J Hum Hypertens
, vol.9
, Issue.6
, pp. 385-390
-
-
Laragh, J.H.1
-
51
-
-
0015333482
-
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease
-
May;
-
Laragh JH, Baer L, Brunner HR, et al. Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease. Am J Med 1972 May; 52 (5): 633-52
-
(1972)
Am J Med
, vol.52
, Issue.5
, pp. 633-652
-
-
Laragh, J.H.1
Baer, L.2
Brunner, H.R.3
-
52
-
-
45149113838
-
Aliskiren: Renin inhibitor for hypertension management
-
Jan;
-
Cheng JW. Aliskiren: Renin inhibitor for hypertension management. Clin Ther 2008 Jan; 30 (1): 31-47
-
(2008)
Clin Ther
, vol.30
, Issue.1
, pp. 31-47
-
-
Cheng, J.W.1
-
53
-
-
50349094508
-
-
Aug 12;
-
Brown MJ. Aliskiren. Circulation 2008 Aug 12; 118 (7): 773-84
-
(2008)
Circulation
, vol.118
, Issue.7
, pp. 773-784
-
-
Aliskiren, B.M.J.1
-
54
-
-
33846996406
-
The (pro)renin receptor: Pathophysiological roles in cardiovascular and renal pathology
-
Mar;
-
Nguyen G. The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology. Curr Opin Nephrol Hypertens 2007 Mar; 16 (2): 129-33
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, Issue.2
, pp. 129-133
-
-
Nguyen, G.1
-
55
-
-
27444447364
-
Renin, prorenin and the putative (pro)renin receptor
-
Nov;
-
Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 2005 Nov; 46 (5): 1069-76
-
(2005)
Hypertension
, vol.46
, Issue.5
, pp. 1069-1076
-
-
Danser, A.H.1
Deinum, J.2
-
56
-
-
47049089844
-
Clinical pharmacokinetics and pharmacodynamics of aliskiren
-
Vaidyanathan S, Jarugula V, Dieterich HA, et al. Clinical pharmacokinetics and pharmacodynamics of aliskiren. Clin Pharmacokinet 2008; 47 (8): 515-31
-
(2008)
Clin Pharmacokinet
, vol.47
, Issue.8
, pp. 515-531
-
-
Vaidyanathan, S.1
Jarugula, V.2
Dieterich, H.A.3
-
57
-
-
34547628374
-
Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment
-
Vaidyanathan S, Bigler H, Yeh C, et al. Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment. Clin Pharmacokinet 2007; 46 (8): 661-75
-
(2007)
Clin Pharmacokinet
, vol.46
, Issue.8
, pp. 661-675
-
-
Vaidyanathan, S.1
Bigler, H.2
Yeh, C.3
-
58
-
-
33846456943
-
Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment
-
Feb;
-
Vaidyanathan S, Warren V, Yeh C, et al. Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment. J Clin Pharmacol 2007 Feb; 47 (2): 192-200
-
(2007)
J Clin Pharmacol
, vol.47
, Issue.2
, pp. 192-200
-
-
Vaidyanathan, S.1
Warren, V.2
Yeh, C.3
-
59
-
-
33749853955
-
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers
-
Nov;
-
Vaidyanathan S, Valencia J, Kemp C, et al. Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. Int J Clin Pract 2006 Nov; 60 (11): 1343-56
-
(2006)
Int J Clin Pract
, vol.60
, Issue.11
, pp. 1343-1356
-
-
Vaidyanathan, S.1
Valencia, J.2
Kemp, C.3
-
60
-
-
54049086657
-
Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: The role of p-glycoprotein in the disposition of aliskiren
-
Nov;
-
Vaidyanathan S, Camenisch G, Schuetz H, et al. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of p-glycoprotein in the disposition of aliskiren. J Clin Pharmacol 2008 Nov; 48 (11): 1323-38
-
(2008)
J Clin Pharmacol
, vol.48
, Issue.11
, pp. 1323-1338
-
-
Vaidyanathan, S.1
Camenisch, G.2
Schuetz, H.3
-
61
-
-
53549097913
-
The development of the direct renin inhibitor aliskiren: Treating hypertension and beyond
-
Sep;
-
Siragy H, Huang J, Lieb DC. The development of the direct renin inhibitor aliskiren: treating hypertension and beyond. Expert Opin Emerg Drugs 2008 Sep; 13 (3): 417-30
-
(2008)
Expert Opin Emerg Drugs
, vol.13
, Issue.3
, pp. 417-430
-
-
Siragy, H.1
Huang, J.2
Lieb, D.C.3
-
62
-
-
34547925543
-
Aliskiren: A review of its use in the management of hypertension
-
Frampton JE, Curran MP. Aliskiren: a review of its use in the management of hypertension. Drugs 2007; 67 (12): 1767-92
-
(2007)
Drugs
, vol.67
, Issue.12
, pp. 1767-1792
-
-
Frampton, J.E.1
Curran, M.P.2
-
63
-
-
33947182655
-
Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension
-
Mar 20;
-
Oh BH, Mitchell J, Herron JR, et al. Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension. J Am Coll Cardiol 2007 Mar 20; 49 (11): 1157-63
-
(2007)
J Am Coll Cardiol
, vol.49
, Issue.11
, pp. 1157-1163
-
-
Oh, B.H.1
Mitchell, J.2
Herron, J.R.3
-
64
-
-
36949012071
-
Safety and efficacy of the oral direct renin inhibitor aliskiren in elderly patients with hypertension
-
Verdecchia P, Calvo C, Mockel V, et al. Safety and efficacy of the oral direct renin inhibitor aliskiren in elderly patients with hypertension. Blood Press 2007; 16 (6): 381-91
-
(2007)
Blood Press
, vol.16
, Issue.6
, pp. 381-391
-
-
Verdecchia, P.1
Calvo, C.2
Mockel, V.3
-
65
-
-
53349092083
-
Direct renin inhibition: An evaluation of the safety and tolerability of aliskiren
-
Sep;
-
Rashid H. Direct renin inhibition: an evaluation of the safety and tolerability of aliskiren. Curr Med Res Opin 2008 Sep; 24 (9): 2627-37
-
(2008)
Curr Med Res Opin
, vol.24
, Issue.9
, pp. 2627-2637
-
-
Rashid, H.1
-
66
-
-
33750357566
-
Aliskiren, a novel orally effective renin inhibitor, exhibits similar pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects
-
Dec;
-
Vaidyanathan S, Jermany J, Yeh C, et al. Aliskiren, a novel orally effective renin inhibitor, exhibits similar pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects. Br J Clin Pharmacol 2006 Dec; 62 (6): 690-8
-
(2006)
Br J Clin Pharmacol
, vol.62
, Issue.6
, pp. 690-698
-
-
Vaidyanathan, S.1
Jermany, J.2
Yeh, C.3
-
67
-
-
33846781398
-
Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension
-
Dec;
-
Kushiro T, Itakura H, Abo Y, et al. Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension. Hypertens Res 2006 Dec; 29 (12): 997-1005
-
(2006)
Hypertens Res
, vol.29
, Issue.12
, pp. 997-1005
-
-
Kushiro, T.1
Itakura, H.2
Abo, Y.3
-
68
-
-
34247867955
-
Direct renin inhibition with aliskiren in obese patients with arterial hypertension
-
May;
-
Jordan J, Engeli S, Boye SW, et al. Direct renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension 2007 May; 49 (5): 1047-55
-
(2007)
Hypertension
, vol.49
, Issue.5
, pp. 1047-1055
-
-
Jordan, J.1
Engeli, S.2
Boye, S.W.3
-
69
-
-
33750289480
-
Aliskiren exhibits similar pharmacokinetics in healthy volunteers and patients with type 2 diabetes mellitus
-
Zhao C, Vaidyanathan S, Yeh CM, et al. Aliskiren exhibits similar pharmacokinetics in healthy volunteers and patients with type 2 diabetes mellitus. Clin Pharmacokinet 2006; 45 (11): 1125-34
-
(2006)
Clin Pharmacokinet
, vol.45
, Issue.11
, pp. 1125-1134
-
-
Zhao, C.1
Vaidyanathan, S.2
Yeh, C.M.3
-
70
-
-
33846421005
-
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker
-
Feb;
-
O'Brien E, Barton J, Nussberger J, et al. Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension 2007 Feb; 49 (2): 276-84
-
(2007)
Hypertension
, vol.49
, Issue.2
, pp. 276-284
-
-
O'Brien, E.1
Barton, J.2
Nussberger, J.3
-
71
-
-
9644287897
-
Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
-
Dec;
-
Azizi M, Menard J, Bissery A, et al. Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol 2004 Dec; 15 (12): 3126-33
-
(2004)
J Am Soc Nephrol
, vol.15
, Issue.12
, pp. 3126-3133
-
-
Azizi, M.1
Menard, J.2
Bissery, A.3
-
72
-
-
0346447922
-
BP lowering with SPP 100: A novel orally active renin inhibitor - a pilot study [abstract]
-
Sept 1;
-
Stanton AV, Jensen C, Mann J, et al. BP lowering with SPP 100: a novel orally active renin inhibitor - a pilot study [abstract]. Hypertension 2001 Sept 1; 38 (3): 526
-
(2001)
Hypertension
, vol.38
, Issue.3
, pp. 526
-
-
Stanton, A.V.1
Jensen, C.2
Mann, J.3
-
73
-
-
0036372173
-
Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): Comparison with enalapril
-
Jan;
-
Nussberger J, Wuerzner G, Jensen C, et al. Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): comparison with enalapril. Hypertension 2002 Jan; 39 (1): E1-8
-
(2002)
Hypertension
, vol.39
, Issue.1
-
-
Nussberger, J.1
Wuerzner, G.2
Jensen, C.3
-
74
-
-
0347479295
-
Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
-
Dec;
-
Stanton A, Jensen C, Nussberger J, et al. Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension 2003 Dec; 42 (6): 1137-43
-
(2003)
Hypertension
, vol.42
, Issue.6
, pp. 1137-1143
-
-
Stanton, A.1
Jensen, C.2
Nussberger, J.3
-
75
-
-
14844363404
-
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
-
Mar 1;
-
Gradman AH, Schmieder RE, Lins RL, et al. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005 Mar 1; 111 (8): 1012-8
-
(2005)
Circulation
, vol.111
, Issue.8
, pp. 1012-1018
-
-
Gradman, A.H.1
Schmieder, R.E.2
Lins, R.L.3
-
76
-
-
33845366982
-
Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
-
Jan;
-
Villamil A, Chrysant SG, Calhoun D, et al. Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. J Hypertens 2007 Jan; 25 (1): 217-26
-
(2007)
J Hypertens
, vol.25
, Issue.1
, pp. 217-226
-
-
Villamil, A.1
Chrysant, S.G.2
Calhoun, D.3
-
77
-
-
36248931230
-
Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy
-
Oct;
-
Drummond W, Munger MA, Rafique Essop M, et al. Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy. J Clin Hypertens (Greenwich) 2007 Oct; 9 (10): 742-50
-
(2007)
J Clin Hypertens (Greenwich)
, vol.9
, Issue.10
, pp. 742-750
-
-
Drummond, W.1
Munger, M.A.2
Rafique Essop, M.3
-
78
-
-
38649102508
-
Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension
-
Dec;
-
Uresin Y, Taylor AA, Kilo C, et al. Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension. J Renin Angiotensin Aldosterone Syst 2007 Dec; 8 (4): 190-8
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, Issue.4
, pp. 190-198
-
-
Uresin, Y.1
Taylor, A.A.2
Kilo, C.3
-
79
-
-
39849089447
-
Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: A 6-month, randomized, double-blind trial
-
Mar;
-
Andersen K, Weinberger MH, Egan B, et al. Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial. J Hypertens 2008 Mar; 26 (3): 589-99
-
(2008)
J Hypertens
, vol.26
, Issue.3
, pp. 589-599
-
-
Andersen, K.1
Weinberger, M.H.2
Egan, B.3
-
80
-
-
34447521458
-
Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
-
Jul 21;
-
Oparil S, Yarows SA, Patel S, et al. Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial. Lancet 2007 Jul 21; 370 (9583): 221-9
-
(2007)
Lancet
, vol.370
, Issue.9583
, pp. 221-229
-
-
Oparil, S.1
Yarows, S.A.2
Patel, S.3
-
81
-
-
33747332458
-
The novel renin inhibitor aliskiren is not associated with rebound effects on blood pressure or plasma renin activity following treatment withdrawal [abstract]
-
Herron J, Mitchell J, Oh B. The novel renin inhibitor aliskiren is not associated with rebound effects on blood pressure or plasma renin activity following treatment withdrawal [abstract]. J Clin Hypertens 2006; 8 (5 Suppl. A): A86-7
-
(2006)
J Clin Hypertens
, vol.8
, Issue.5 SUPPL. A
-
-
Herron, J.1
Mitchell, J.2
Oh, B.3
-
82
-
-
44849114597
-
Aliskiren combined with losartan in type 2 diabetes and nephropathy
-
Jun 5;
-
Parving HH, Persson F, Lewis JB, et al. Aliskiren combined with losartan in type 2 diabetes and nephropathy. N Engl J Med 2008 Jun 5; 358 (23): 2433-46
-
(2008)
N Engl J Med
, vol.358
, Issue.23
, pp. 2433-2446
-
-
Parving, H.H.1
Persson, F.2
Lewis, J.B.3
-
83
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Sep 20;
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001 Sep 20; 345 (12): 861-9
-
(2001)
N Engl J Med
, vol.345
, Issue.12
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
|