Accuracy of whole-body low-dose multidetector CT (WBLDCT) versus skeletal survey in the detection of myelomatous lesions, and correlation of disease distribution with whole-body MRI (WBMRI)

Skeletal Radiology

Volumn 38, Issue 3, 2009, Pages 225-236

  Gleeson, T G ^a,d   Moriarty, J ^a   Shortt, C P ^a   Gleeson, J P ^b   Fitzpatrick, P ^c   Byrne, B ^a   McHugh, J ^a   O'Connell, M ^a   O'Gorman, P ^a   Eustace, S J ^a  

^a MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY OF LIMERICK   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d ST PAUL S HOSPITAL   (Canada)

Author keywords

Computed tomography; MRI; Multiple myeloma; Radiation dosage; Radiographs; Whole body imaging

Indexed keywords

ADULT; AGED; ARTICLE; BONE ATROPHY; BONE MARROW BIOPSY; CANCER STAGING; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICAL BONE; DIAGNOSTIC ACCURACY; EVALUATION; FEMALE; GOLD STANDARD; HUMAN; IMAGE QUALITY; LOW ENERGY RADIATION; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIPLE MYELOMA; OSTEOLYSIS; PATIENT REFERRAL; PLASMA CELL DYSCRASIA; PRIORITY JOURNAL; RADIATION DOSE; RADIOLOGIST; RANDOMIZED CONTROLLED TRIAL; SIGNAL DETECTION; WHOLE BODY IMAGING; WHOLE BODY MRI;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; BONE MARROW; CHI-SQUARE DISTRIBUTION; FEASIBILITY STUDIES; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE MYELOMA; NEOPLASM STAGING; RADIATION DOSAGE; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 58849133680     PISSN: 03642348     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00256-008-0607-4     Document Type: Article

References (28)

1. A Baur A Stabler D Nagel 2002 Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon? Cancer 95 1334 1345
2. BGM Durie 2006 The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system Eur J Cancer 42 1539 1543
3. AH Mahnken JE Wildberger G Gehbauer 2002 Multidetector CT of the spine in multiple myeloma: comparison with MR imaging and radiography AJR 178 1429 1426
4. PG Richardson P Sonneveld M Schuster 2007 Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial Blood 110 3557 3560
5. K Orchard S Barrington J Buscombe A Hilson HG Prentice A Metha 2002 Fluoro-deoxyglucose positron emission tomography imaging for the detection of occult disease in multiple myeloma Br J Haematol 117 133 135
6. MA Bredella L Steinbach G Caputo G Segall R Hawkins 2005 Value of FDG PET in the assessment of patients with multiple myeloma AJR 184 1199 1204
7. BG Durie AD Waxman A D'Agnolo CM Williams 2002 Whole-body 18F-FDG PET identifies high-risk myeloma J Nucl Med 43 1457 1463
8. G Antoch FM Vogt LS Freudenberg 2003 Whole-body dual-modality PET/CT and whole-body MRI for tumour staging in oncology JAMA 290 3199 3206
9. DJ Brenner EJ Hall D Phil 2007 Computed tomography-an increasing source of radiation exposure N Engl J Med 357 2277 2284
10. E Cardis M Vrijheid M Blettner 2007 The 15-country collaborative study of cancer risk in radiation workers in the nuclear industry: estimates of radiation-related cancer risks Radiation Research 167 396 416
11. M Horger CD Claussen U Bross-Bach 2005 Whole-body low-dose multidetector row-CT in the diagnosis of multiple myeloma: an alternative to conventional radiography Eur J Rad 54 289 297
12. Gleeson TG, Byrne B, Kenny P, Fitzpatrick P, O'Gorman P, Eustace SJ. Dose Optimization in Whole Body Low Dose Multidetector CT (MDCT) in the Staging of Multiple Myeloma. Scholars and Awards Session: Residents in Radiology Awards. ARRS Annual Meeting, Orlando, 8th May, 2007.
13. Buhmann S, Schoenberg S, Becker CR, Lang N, Reiser MF, Baur-Melnyk A. Whole-body imaging approach of patients with multiple myeloma: comparing MR imaging with MD-CT. Eur Radiol 2006; (Suppl 1): B-003.
14. A Baur-Melnyk S Buhmann C Becker 2008 Whole-body MRI versus whole-body MDCT for staging of multiple myeloma AJR 190 1097 1104
15. GP Schmidt MF Reiser AB Baur-Melnyk 2007 Whole-body imaging of the musculoskeletal system: the value of MR imaging Skeletal Radiol 36 1109 1119
16. R Walker B Barlogie J Haessler 2007 Magnetic resonance imaging in multiple myeloma: diagnostic and clinical implications J Clin Oncol 25 1121 1128
17. BGM Durie 1986 Staging and kinetics of multiple myeloma Sem Oncol 13 300 309
18. P Kropil R Fenk LB Fritz 2008 Comparison of whole-body 64-slice multidetector computed tomography and conventional radiography in staging of multiple myeloma Eur Radiol 18 51 58
19. W Huda A Vance 2007 Patient radiation doses from adult and pediatric CT AJR 188 540 546
20. FE Lecouvet J Malghem L Michaux 2000 Skeletal survey in advanced multiple myeloma: radiographic versus MR imaging survey Br J Haematol 106 35 39
21. Weininger M, Lauterbach B, Knop S, et al. Whole-body MRI of multiple myeloma: Comparison of different MRI sequences in assessment of different growth patterns. Eur J Radiol 2007, December 18 (e-publication ahead of print).
22. N Ghanem C Lohrmann M Engelhardt 2006 Whole-body MRI in the detection of bone marrow infiltration in patients with plasma cell neoplasms in comparison to the radiological skeletal survey Eur Radiol 16 1005 1014
23. A Baur-Melnyk S Buhmann HR Durr M Reiser 2005 Role of MRI for the diagnosis and prognosis of multiple myeloma Eur J Rad 55 56 63
24. M Horger L Kna B Denecke 2007 The benefit of using whole-body, low-dose, nonenhanced, multidetector computed tomography for follow-up and therapy response monitoring in patients with multiple myeloma Cancer 109 1616 1626
25. M Chassang A Grimaud JM Cucchi 2007 Can low-dose computed tomographic scan of the spine replace conventional radiography? An evaluation based on imaging myelomas, bone metastases, and fractures from osteoporosis Clinical Imaging 31 225 227
26. SJ Golding PC Shrimpton 2002 Radiation dose in CT: are we meeting the challenge? (commentary) Br J Radiol 75 1 4
27. MA Lewis 2005 Patient dose reduction in CT (Commentary) Br J Radiol 78 880 883
28. JR Mayo J Aldrich NL Muller 2003 Radiation exposure at chest CT: a statement of the Fleischner Society Radiology 228 15 21