Relationship between right cervical vagus nerve stimulation and atrial fibrillation inducibility: Therapeutic intensities do not increase arrhythmogenesis

Heart Rhythm

Volumn 6, Issue 2, 2009, Pages 244-250

  Zhang, Youhua ^a   Ilsar, Itamar ^b   Sabbah, Hani N ^b   Ben David, Tamir ^c   Mazgalev, Todor N ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b HENRY FORD HEALTH SYSTEM   (United States)

^c BioControl Medical Ltd   (Israel)

Author keywords

Atrial fibrillation; Electrophysiology; Heart rate; Vagal stimulation; Vagus nerve

Indexed keywords

ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CAROTID SINUS NERVE; CERVICAL SPINAL CORD; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; DOG; HEART ATRIUM FIBRILLATION; HEART ATRIUM PACEMAKER; HEART RATE; IMPLANTATION; NONHUMAN; PERIODICITY; PRIORITY JOURNAL; SINUS NODE; SINUS RHYTHM; TITRIMETRY; TREATMENT DURATION; TREATMENT RESPONSE; VAGUS NERVE; VAGUS NERVE STIMULATION;

ANALYSIS OF VARIANCE; ANIMALS; ATRIAL FIBRILLATION; CROSS-OVER STUDIES; DOGS; ELECTROCARDIOGRAPHY, AMBULATORY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; VAGUS NERVE; VAGUS NERVE STIMULATION;

EID: 58849127466     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2008.10.043     Document Type: Article

References (35)

1. Zhang Y., and Mazgalev T.N. Role of the vagus in AF: pathophysiology and therapeutic applications. In: Natale A., and Jalife J. (Eds). Atrial Fibrillation: From Bench to Bedside (2008), Humana Press, Totowa, NJ 115-131
2. Andrus E.C., and Carter E.P. The refractory period of the normally-beating dog's auricle; with a note on the occurrence of auricular fibrillation following a single stimulus. J Exp Med 51 (1930) 357-368
3. Schauerte P., Scherlag B.J., Pitha J., et al. Catheter ablation of cardiac autonomic nerves for prevention of vagal atrial fibrillation. Circulation 102 (2000) 2774-2780
4. Lemola K., Chartier D., Yeh Y.H., et al. Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia. Circulation 117 (2008) 470-477
5. Scherlag B.J., Nakagawa H., Jackman W.M., et al. Electrical stimulation to identify neural elements on the heart: their role in atrial fibrillation. J Interv Card Electrophysiol 1 13 (2005) 37-42
6. Liu L., and Nattel S. Differing sympathetic and vagal effects on atrial fibrillation in dogs: role of refractoriness heterogeneity. Am J Physiol 273 (1997) H805-H816
7. Chiou C.W., Eble J.N., and Zipes D.P. Efferent vagal innervation of the canine atria and sinus and atrioventricular nodes. The third fat pad. Circulation 95 (1997) 2573-2584
8. Li M., Zheng C., Sato T., et al. Vagal nerve stimulation markedly improves long-term survival after chronic heart failure in rats. Circulation 109 (2004) 120-124
9. Sabbah H.N., Rastogi S., Mishra S., et al. Long-term therapy with neuroselective electric vagus nerve stimulation improves LV function and attenuates LV global remodeling in dogs with chronic heart failure (Abstract). Eur J Heart Failure 4 (2005) 166-167
10. Vanoli E., De Ferrari G.M., Stramba-Badiale M., et al. Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction. Circ Res 68 (1991) 1471-1481
11. Zamotrinsky A.V., Kondratiev B., and de Jong J.W. Vagal neurostimulation in patients with coronary artery disease. Auton Neurosci 88 (2001) 109-116
12. Schwartz P.J., De Ferrari G.M., Sanzo A., et al. Long term vagal stimulation in patients with advanced heart failure. First experience in man. Eur J Heart Fail 10 (2008) 884-891
13. Nadeau R., Cardinal R., Armour J.A., et al. Cervical vagosympathetic and mediastinal nerves activation effects on atrial arrhythmia formation. Anadolu Kardiyol Derg 7 Suppl 1 (2007) 34-36
14. Oh S., Zhang Y., Bibevski S., et al. Vagal denervation and atrial fibrillation inducibility: epicardial fat pad ablation does not have long-term effects. Heart Rhythm 3 (2006) 701-708
15. Coumel P. Cardiac arrhythmias and the autonomic nervous system. J Cardiovasc Electrophysiol 4 (1993) 338-355
16. Bettoni M., and Zimmermann M. Autonomic tone variations before the onset of paroxysmal atrial fibrillation. Circulation 105 (2002) 2753-2759
17. Fioranelli M., Piccoli M., Mileto G.M., et al. Analysis of heart rate variability five minutes before the onset of paroxysmal atrial fibrillation. Pacing Clin Electrophysiol 22 (1999) 743-749
18. Coccagna G., Capucci A., Bauleo S., et al. Paroxysmal atrial fibrillation in sleep. Sleep 20 (1997) 396-398
19. Wu T.J., Kim Y.H., Yashima M., et al. Progressive action potential duration shortening and the conversion from atrial flutter to atrial fibrillation in the isolated canine right atrium. J Am Coll Cardiol 38 (2001) 1757-1765
20. Tan A.Y., Zhou S., Ogawa M., et al. Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines. Circulation 118 (2008) 916-925
21. Pappone C., Santinelli V., Manguso F., et al. Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation 109 (2004) 327-334
22. Scanavacca M., Pisani C.F., Hachul D., et al. Selective atrial vagal denervation guided by evoked vagal reflex to treat patients with paroxysmal atrial fibrillation. Circulation 114 (2006) 876-885
23. Verma A., Saliba W.I., Lakkireddy D., et al. Vagal responses induced by endocardial left atrial autonomic ganglion stimulation before and after pulmonary vein antrum isolation for atrial fibrillation. Heart Rhythm 4 (2007) 1177-1182
24. Katritsis D., Giazitzoglou E., Sougiannis D., et al. Anatomic approach for ganglionic plexi ablation in patients with paroxysmal atrial fibrillation. Am J Cardiol 102 (2008) 330-334
25. Hirose M., Leatmanoratn Z., Laurita K.R., et al. Partial vagal denervation increases vulnerability to vagally induced atrial fibrillation. J Cardiovasc Electrophysiol 13 (2002) 1272-1279
26. Shafique S., and Dalsing M.C. Vagus nerve stimulation therapy for treatment of drug-resistant epilepsy and depression. Perspect Vasc Surg Endovasc Ther 18 (2006) 323-327
27. Srinivasan B., and Awasthi A. Transient atrial fibrillation after the implantation of a vagus nerve stimulator. Epilepsia 45 (2004) 1645
28. Braun A.P., Phan T.D., and Sulakhe P.V. Muscarinic acetylcholine receptors in the sino-atrial node and right atrium of bovine heart. Eur J Pharmacol 189 (1990) 201-215
29. Beau S.L., Hand D.E., Schuessler R.B., et al. Relative densities of muscarinic cholinergic and beta-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. Circ Res 77 (1995) 957-963
30. Tsutsumi T., Ide T., Yamato M., et al. Modulation of the myocardial redox state by vagal nerve stimulation after experimental myocardial infarction. Cardiovasc Res 77 (2008) 713-721
31. Gupta R.C., Imai M., Jiang A.J., et al. Chronic therapy with selective electric vagus nerve stimulation normalizes plasma concentration of tissue necrosis factor-α, interleukin-6 and B-type natriuretic peptide in dogs with heart failure. J Am Coll Cardiol 47 (2006) 77A
32. Tracey K.J. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 117 (2007) 289-296
33. Zhang Y., Yamada H., Bibevski S., et al. Chronic atrioventricular nodal vagal stimulation: first evidence for long-term ventricular rate control in canine atrial fibrillation model. Circulation 112 (2005) 2904-2911
34. Bianchi S., Rossi P., Scala A.D., et al. Endocardial transcatheter stimulation of the AV nodal fat pad: stabilization of rapid ventricular rate response during atrial fibrillation in left ventricular failure. J Cardiovasc Electrophysiol 20 (2009) 103-105
35. Ardell J.L., and Randall W.C. Selective vagal innervation of sinoatrial and atrioventricular nodes in canine heart. Am J Physiol 251 (1986) H764-H773