Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training

International Journal of Sport Nutrition and Exercise Metabolism

Volumn 19, Issue 1, 2009, Pages 79-96

  Cornish, Stephen M ^a   Candow, Darren G ^b   Jantz, Nathan T ^a   Chilibeck, Philip D ^a   Little, Jonathan P ^a   Forbes, Scott ^a   Abeysekara, Saman ^a   Zello, Gordon A ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF REGINA   (Canada)

Author keywords

3 methylhistidine; Bone; Exercise; Muscle; Nutraceutical; Oxidative stress

Indexed keywords

3 METHYLHISTIDINE; 8 ISOPROSTANE; AMINO TERMINAL TELOPEPTIDE; CONJUGATED LINOLEIC ACID; CREATINE; NUTRACEUTICAL;

ADULT; ANTHROPOMETRY; ARTICLE; BODY COMPOSITION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EXERCISE; FEMALE; HUMAN; KIDNEY FUNCTION; MALE; MICROALBUMINURIA; NORMAL HUMAN; OSTEOLYSIS; OXIDATIVE STRESS; PLETHYSMOGRAPHY; PROTEIN DEGRADATION; RANDOMIZED CONTROLLED TRIAL; STRENGTH; SUPPLEMENTATION; TRAINING; WHEY;

EID: 58849125330     PISSN: 1526484X     EISSN: 15432742     Source Type: Journal    
DOI: 10.1123/ijsnem.19.1.79     Document Type: Article

References (49)

1. Antolic, A., Roy, B.D., Tarnopolsky, M.A., Zernicke, R.F., Wohl, G.R., Shaughnessy, S.G., et al. (2007). Creatine monohydrate increases bone mineral density in young Sprague-Dawley rats. Medicine and Science in Sports and Exercise, 39, 816-820.
2. Azain, M.J., Hausman, D.B., Sisk, M.B., Flatt, W.P., & Jewell, D.E. (2000). Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. The Journal of Nutrition, 130, 1548-1554.
3. Basu, S., Riserus, U., Turpeinen, A., & Vessby, B. (2000). Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. Clinical Science (London, England: 1979), 99, 511-516.
4. Bhattacharya, A., Banu, J., Rahman, M., Causey, J., & Fernandes, G. (2006). Biological effects of conjugated linoleic acids in health and disease. The Journal of Nutritional Biochemistry, 17, 789-810.
5. Burke, D.G., Chilibeck, P.D., Davidson, K.S., Candow, D.G., Farthing, J., & Smith-Palmer, T. (2001). The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength. International Journal of Sport Nutrition and Exercise Metabolism, 11, 349-364.
6. Burke, D.G., Chilibeck, P.D., Parise, G., Candow, D.G., Mahoney, D., & Tarnopolsky, M. (2003). Effect of creatine and weight training on muscle creatine and performance in vegetarians. Medicine and Science in Sports and Exercise, 35, 1946-1955.
7. Burke, D.G., Silver, S., Holt, L.E., Smith Palmer, T., Culligan, C.J., & Chilibeck, P.D. (2000). The effect of continuous low dose creatine supplementation on force, power, and total work. International Journal of Sport Nutrition and Exercise Metabolism, 10, 235-244.
8. Candow, D.G., Burke, N.C., Smith-Palmer, T., & Burke, D.G. (2006). Effect of whey and soy protein supplementation combined with resistance training in young adults. International Journal of Sport Nutrition and Exercise Metabolism, 16, 233-244.
9. Candow, D.G., & Chilibeck, P.D. (2005). Differences in size, strength, and power of upper and lower body muscle groups in young and older men. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 60, 148-156.
10. Candow, D.G., Chilibeck, P.D., Burke, D.G., Davison, K.S., & Smith-Palmer, T. (2001). Effect of glutamine supplementation combined with resistance training in young adults. European Journal of Applied Physiology, 86, 142-149.
11. Chilibeck, P.D., Chrusch, M.J., Chad, K.E., Davison, K.S., & Burke, D.G. (2005). Creatine monohydrate and resistance training increase bone mineral content and density in older men. The Journal of Nutrition, Health & Aging, 9, 352-353.
12. Chilibeck, P.D., Stride, D., Farthing, J.P., & Burke, D.G. (2004). Effect of creatine ingestion after exercise on muscle thickness in males and females. Medicine and Science in Sports and Exercise, 36, 1781-1788.
13. Chrusch, M.J., Chilibeck, P.D., Chad, K.E., Davison, K.S., & Burke, D.G. (2001). Creatine supplementation combined with resistance training in older men. Medicine and Science in Sports and Exercise, 33, 2111-2117.
14. DeLany, J.P., Blohm, F., Truett, A.A., Scimeca, J.A., & West, D.B. (1999). Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. The American Journal of Physiology, 276, R1172-R1179.
15. Du, M., & Ahn, D.U. (2002). Effect of dietary conjugated linoleic acid on the growth rate of live birds and on the abdominal fat content and quality of broiler meat. Poultry Science, 81, 428-433.
16. Dugan, M., Aalhus, J., Jeremiah, L., Kramer, J., & Schaefer, A. (1999). The effects of feeding conjugated linoleic acid on subsequent pork quality. Canadian Journal of Animal Science, 79, 45-51.
17. Dugan, M., Aalhus, J., Schaefer, A., & Kramer, J. (1997). The effect of feeding conjugated linoleic acid on fat to lean repartitioning and feed conversion in pigs. Canadian Journal of Animal Science, 77, 723-725.
18. Esmarck, B., Andersen, J.L., Olsen, S., Richter, E.A., Mizuno, M., & Kjaer, M. (2001). Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans. The Journal of Physiology, 535, 301-311.
19. Gaullier, J.M., Halse, J., Hoivik, H.O., Hoye, K., Syvertsen, C., Nurminiemi, M., et al. (2007). Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese. The British Journal of Nutrition, 97, 550-560.
20. Gerber, I., ap Gwynn, I., Alini, M., & Wallimann, T. (2005). Stimulatory effects of creatine on metabolic activity, differentiation and mineralization of primary osteoblast-like cells in monolayer and micromass cell cultures. European Cells & Materials, 10, 8-22.
21. Hartman, J.W., Tang, J.E., Wilkinson, S.B., Tarnopolsky, M.A., Lawrence, R.L., Fullerton, A.V., et al. (2007). Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. The American Journal of Clinical Nutrition, 86, 373-381.
22. Hickson, J.F., Jr., & Hinkelmann, K. (1985). Exercise and protein intake effects on urinary 3-methylhistidine excretion. The American Journal of Clinical Nutrition, 41, 246-253.
23. Kreider, R.B., Ferreira, M., Wilson, M., Grindstaff, P., Plisk, A., Reinardy, J., et al. (1998). Effects of creatine supplementation on body composition, strength, and sprint performance. Medicine and Science in Sports and Exercise, 30, 73-82.
24. Kreider, R.B., Ferreira, M.P., Greenwood, M., Wilson, M., & Almada, A.L. (2002). Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. Journal of Strength and Conditioning Research, 16, 325-334.
25. Lemon, P.W. (1998). Effects of exercise on dietary protein requirements. International Journal of Sport Nutrition, 8, 426-447.
26. Louis, M., Lebacq, J., Poortmans, J.R., Belpaire-Dethiou, M.C., Devogelaer, J.P., Van Hecke, P., et al. (2003). Beneficial effects of creatine supplementation in dystrophic patients. Muscle & Nerve, 27, 604-610.
27. Lukaski, H.C., Mendez, J., Buskirk, E.R., & Cohn, S.H. (1981). Relationship between endogenous 3-methylhistidine excretion and body composition. The American Journal of Physiology, 240, E302-E307.
28. Nagao, K., Wang, Y.M., Inoue, N., Han, S.Y., Buang, Y., Noda, T., et al. (2003). The 10trans, 12cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats. Nutrition (Burbank, Los Angeles County, Calif.), 19, 652-656.
29. Navarro, V., Fernandez-Quintela, A., Churruca, I., & Portillo, M.P. (2006). The body fat-lowering effect of conjugated linoleic acid: A comparison between animal and human studies. Journal of Physiology and Biochemistry, 62, 137-147.
30. Nazare, J.A., de la Perriere, A.B., Bonnet, F., Desage, M., Peyrat, J., Maitrepierre, C., et al. (2007). Daily intake of conjugated linoleic acid-enriched yoghurts: Effects on energy metabolism and adipose tissue gene expression in healthy subjects. The British Journal of Nutrition, 97, 273-280.
31. Ohnuki, K., Haramizu, S., Ishihara, K., & Fushiki, T. (2001). Increased energy metabolism and suppressed body fat accumulation in mice by a low concentration of conjugated linoleic acid. Bioscience, Biotechnology, and Biochemistry, 65, 2200-2204.
32. Parise, G., Mihic, S., MacLennan, D., Yarasheski, K.E., & Tarnopolsky, M.A. (2001). Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis. Journal of Applied Physiology, 91, 1041-1047.
33. Park, Y., Albright, K.J., Liu, W., Storkson, J.M., Cook, M.E., & Pariza, M.W. (1997). Effect of conjugated linoleic acid on body composition in mice. Lipids, 32, 853-858.
34. Pinkoski, C., Chilibeck, P.D., Candow, D.G., Esliger, D., Ewaschuk, J.B., Facci, M., et al. (2006). The effects of conjugated linoleic acid supplementation during resistance training. Medicine and Science in Sports and Exercise, 38, 339-348.
35. Pistilli, E.E., Jackson, J.R., & Alway, S.E. (2006). Death receptor-associated pro-apoptotic signaling in aged skeletal muscle. Apoptosis, 11, 2115-2126.
36. Pline, K.A., & Smith, C.L. (2005). The effect of creatine intake on renal function. The Annals of Pharmacotherapy, 39, 1093-1096.
37. Rennie, M.J., & Tipton, K.D. (2000). Protein and amino acid metabolism during and after exercise and the effects of nutrition. Annual Review of Nutrition, 20, 457-483.
38. 10, and lipoic acid in mitochondrial disorders. Muscle & Nerve, 35, 235-242.
39. Song, H.J., Grant, I., Rotondo, D., Mohede, I., Sattar, N., Heys, S.D., et al. (2005). Effect of CLA supplementation on immune function in young healthy volunteers. European Journal of Clinical Nutrition, 59, 508-517.
40. Steck, S.E., Chalecki, A.M., Miller, P., Conway, J., Austin, G.L., Hardin, J.W., et al. (2007). Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. The Journal of Nutrition, 137, 1188-1193.
41. Tarnopolsky, M., Zimmer, A., Paikin, J., Safdar, A., Aboud, A., Pearce, E., et al. (2007). Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults. PLoS ONE, 2, e991.
42. Tarnopolsky, M.A., Atkinson, S.A., MacDougall, J.D., Chesley, A., Phillips, S., & Schwarcz, H.P. (1992). Evaluation of protein requirements for trained strength athletes. Journal of Applied Physiology, 73, 1986-1995.
43. Tarnopolsky, M.A., Mahoney, D.J., Vajsar, J., Rodriguez, C., Doherty, T.J., Roy, B.D., et al. (2004). Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy. Neurology, 62, 1771-1777.
44. Thomas, S., Reading, J., & Shephard, R.J. (1992). Revision of the Physical Activity Readiness Questionnaire (PAR-Q). Canadian Journal of Sport Sciences, 17, 338-345.
45. Thorsteinsdottir, B., Grande, J.P., & Garovic, V.D. (2006). Acute renal failure in a young weight lifter taking multiple food supplements, including creatine monohydrate. Journal of Renal Nutrition, 16, 341-345.
46. Tipton, K.D., Ferrando, A.A., Phillips, S.M., Doyle, D., Jr., & Wolfe, R.R. (1999). Post-exercise net protein synthesis in human muscle from orally administered amino acids. The American Journal of Physiology, 276, E628-E634.
47. Tipton, K.D., Rasmussen, B.B., Miller, S.L., Wolf, S.E., Owens-Stovall, S.K., Petrini, B.E., et al. (2001). Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. American Journal of Physiology. Endocrinology and Metabolism, 281, E197-E206.
48. Wassner, S.J., Schlitzer, J.L., & Li, J.B. (1980). A rapid, sensitive method for the determination of 3-methylhistidine levels in urine and plasma using high-pressure liquid chromatography. Annals of Biochemistry, 104, 284-289.
49. West, D.B., Delany, J.B., Camet, P.M., Blohm, F., Truett, A.A., & Scimeca, J. (1998). Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. The American Journal of Physiology, 275, R667-R672.