The clinical impact of an early decline in kidney function in patients following heart transplantation

American Journal of Transplantation

Volumn 9, Issue 2, 2009, Pages 348-354

  Cantarovich, M ^a   Hirsh, A ^a   Alam, A ^a   Giannetti, N ^a   Cecere, R ^a   Carroll, P ^a   Edwardes, M E ^b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b Everest Clinical Research Services   (Canada)

Author keywords

Chronic dialysis; Creatinine clearance; Heart transplantation; Kidney transplantation; Mortality; Survival

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; DACLIZUMAB; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; THYMOCYTE ANTIBODY;

ADULT; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; DIALYSIS; DISEASE COURSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FAILURE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS;

COHORT STUDIES; CREATININE; FEMALE; HEART TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; RENAL INSUFFICIENCY; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME;

EID: 58849124839     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02490.x     Document Type: Article

References (26)

1. Macoviak JA, Oyer PE, Stinson EB, Jamieson SW, Baldwin JC, Shumway NE. Four years experience with cyclosporine for heart and heart-lung transplantation. Transplant Proc 1985 17 : 97 99.
2. Zietse R, Balk AH, vd Dorpel MA, Meeter K, Bos E, Weimar W. Time course of the decline in renal function in cyclosporine-treated heart transplant recipients. Am J Nephrol 1994 14 : 1 5.
3. Rubel JR, Milford EL, McKay DB, Jarcho JA. Renal insufficiency and end-stage renal disease in the heart transplant population. J Heart Lung Transplant 2004 23 : 289 300.
4. Ojo AO, Held PJ, Port FK et al. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med 2003 349 : 931 940.
5. Taylor DO, Edwards LB, Boucek MM et al. Registry of the international society for heart and lung transplantation: Twenty-fourth official adult heart transplant report-2007. J Heart Lung Transplant 2007 26 : 769 781.
6. Frimat L, Villemot JP, Cormier L et al. Treatment of end-stage renal failure after heart transplantation. Nephrol Dial Transplant 1998 13 : 2905 2908.
7. Alam A, Badovinac K, Ivis F, Trpeski L, Cantarovich M. The outcome of heart transplant recipients following the development of end stage renal disease: Analysis of the Canadian organ replacement register. Am J Transplant 2007 7 : 461 465.
8. Lindelow B, Bergh CH, Herlitz H, Waagstein F. Predictors and evolution of renal function during 9 years following heart transplantation. J Am Soc Nephrol 2000 11 : 951 957.
9. Satchithananda DK, Parameshwar J, Sharples L et al. The incidence of end-stage renal failure in 17 years of heart transplantation: A single center experience. J Heart Lung Transplant 2002 21 : 651 657.
10. Greenberg A, Thompson ME, Griffith BJ et al. Cyclosporine nephrotoxicity in cardiac allograft patients - a seven-year follow-up. Transplantation 1990 50 : 589 593.
11. van Gelder T, Balk AH, Zietse R, Hesse C, Mochtar B, Weimar W. Renal insufficiency after heart transplantation: A case-control study. Nephrol Dial Transplant 1998 13 : 2322 2326.
12. Myers BD, Sibley R, Newton L et al. The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int 1988 33 : 590 600.
13. Myers BD, Ross J, Newton L, Luetscher J, Perlroth M. Cyclosporine associated chronic nephropathy. N Engl J Med 1984 311 : 699 705.
14. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976 16 : 31 41.
15. Cantarovich M, Fitchett D, Latter D. Cyclosporine A trough levels, acute rejection and renal dysfunction after heart transplantation. Transplantation 1995 59 : 444 447.
16. Arora S, Andreassen A, Simonsen S et al. Prognostic importance of renal function 1 year after heart transplantation for all-cause and cardiac mortality and development of allograft vasculopathy. Transplantation 2007 84 : 149 154.
17. Palestine AG, Austin HA, Balow JE et al. Renal histopathologic alterations in patients treated with cyclosporine for uveitis. N Engl J Med 1986 314 : 1293 1298.
18. Greenberg A, Egel JW, Thompson ME et al. Early and late forms of cyclosporine nephrotoxicity: Studies in cardiac transplant recipients. Am J Kidney Dis 1987 9 : 12 22.
19. Griffith BP, Hardesty RL, Lee A et al. Management of cyclosporine toxicity by reduced dosage and azathioprine. Heart Transplant 1985 4 : 410 413.
20. Cantarovich M, Ross H, Arizón JM et al. Benefit of Neoral® C2 monitoring in de novo cardiac transplant recipients receiving basiliximab-induction. Transplantation 2008 85 : 992 999.
21. Dureau G, Obadia JF, Chuzel M, Boissonnat P. Introduction of mycophenolate mofetil and cyclosporine withdrawal in heart transplant patients with progressive deteriorating renal function. Transplant Proc 2000 32 : 461 462.
22. Gleissner CA, Doesch A, Ehlermann P. Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy. Am J Transplant 2006 6 : 2750 2758.
23. Cantarovich M, Giannetti N, Routy JP et al. Calcineurin inhibitor substitution ("retirement") with anti-CD25 monoclonal antibodies: A novel strategy in long-term heart transplant patients with progressive renal dysfunction. Am J Transplant 2006 Suppl 6 713.
24. Cantarovich M, Besner JG, Barkun J, Elstein E, Loertscher R. Two hour cyclosporine level determination is the appropriate tool to monitor Neoral therapy. Clin Transplant 1998 12 : 243 249.
25. Falkenhain ME, Cosio FG, Sedmak DD. Progressive histologic injury in kidneys from heart and liver transplant recipients receiving cyclosporine. Transplantation 1996 62 : 364 370.
26. Lin J, Valeri A, Markowitz G, D'Agati V, Cohen D, Radhakrishnan J. Angiotensin converting enzyme inhibition in chronic allograft nephropathy. Transplantation 2002 73 : 783 788.