Effects of creatinin phosphokinase competitive inhibitor on system and tissue energy metabolism in rats in the norm and during unloading

Aviakosmicheskaya i Ekologicheskaya Meditsina

Volumn 42, Issue 4, 2008, Pages 35-39

  Mukhina, A M ^a   Nemirovskaya, T L ^a   Larina, I M ^a   Pastushkova, L Kh ^a   Vasilieva, G Yu ^a   Istomina, V E ^a   Veselova, O M ^a   Turtikova, O V ^a   Shenkman, B S ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMP ACTIVATED PROTEIN KINASE KINASE; AMP-ACTIVATED PROTEIN KINASE KINASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; GLUCOSE; GUANIDINE DERIVATIVE; GUANIDINOPROPIONIC ACID; PROPIONIC ACID DERIVATIVE; PROTEIN KINASE; SUCCINATE DEHYDROGENASE;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENERGY METABOLISM; ENZYME ACTIVATION; FOLLOW UP; IMMOBILIZATION; IMMUNOHISTOCHEMISTRY; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; METABOLISM; METHODOLOGY; PHYSIOLOGY; RAT; SKELETAL MUSCLE; WEIGHTLESSNESS; WISTAR RAT;

ANIMALS; ASPARTATE AMINOTRANSFERASES; CREATINE KINASE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; ENZYME ACTIVATION; FOLLOW-UP STUDIES; GLUCOSE; GUANIDINES; HINDLIMB SUSPENSION; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAMUSCULAR; MALE; MUSCLE, SKELETAL; PROPIONIC ACIDS; PROTEIN KINASES; RATS; RATS, WISTAR; SUCCINATE DEHYDROGENASE; WEIGHTLESSNESS SIMULATION;

EID: 58849124350     PISSN: 0233528X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Russian source
2. Russian source
3. Russian source
4. Russian source
5. Bergeron R., Ren J.M., Cadman K.S. et al. Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis//Am. J. Physiol. Endocrinol. Metab. 2001. V. 281. No 6. P. E1340-E1346.
6. Bergeron R., Russell R.R., Young LH. et al. Effect of AMPK activation on muscle glucose metabolism in conscious rats//Am. J. Physiol. 1999. V. 276. No 5. Pt. 1. P. E938-E944.
7. Freyssenet D., Berthon P., Barthélémy J.C. et al. Energetic status and mitochondrial oxidative capacity of rat skeletal muscle in response to creatine analogue ingestion//Biochim. Biophys. Acta. 1995. Mar. 14. V. 1228. No 2-3. P. 211-215.
8. Grigoriev A.I., Kaplansky A.S., Durnova G.N., Popova LA. Biochemical and morphological stress-reactions in humans and animals in microgravity//Acta Astronaut. 1997. V. 40. No 1. P. 51-56.
9. Grindeland R.E., Popova I.A., Vasques M., Arnaud S.B. Cosmos 1887 mission overview: effects of microgravity on rat body and adrenal weights and plasma constituents//FASEB J. 1990. Jan. V. 4. No 1. P. 105-109.
10. Leclerc I., Viollet. B., da Silva Xavier G. et al. Role of AMP-activated protein kinase in the regulation of gene transcription//Biochem. Soc. Transact. 2002. V. 30. Pt. 2. P. 307-311.
11. Merrill A.H. Jr., Wang E., Mullins R.E. et al. Analyses of plasma for metabolic and hormonal changes in rats flown aboard COSMOS 2044//J. Appl. Physiol. 1992. Aug. V. 73. No 2 (Suppl.). P. 132S-135S.
12. Popova I.A., Grigoriev A.I. Metabolic effects of spaceflight: Cosmos missions overview//Adv. Space Biol. Med. 1994. V. 4. P. 69-83.
13. Putman C.T., Kiricsi M., Pearcey J. et al. AMPK activation increases uncoupling protein-3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions//J. Physiol. 2003. V. 551. Pt. 1. P. 169-178.
14. Richter E.A., Nielsen J.N., Jørgensen S.B. et al. Signalling to glucose transport in skeletal muscle during exercise//Acta Physiol. Scand. 2003. V. 178. P. 329-335.
15. Ruderman N.B., Park H., Kaushik V.K. et al. AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise//Acta Physiol. Scand. 2003. V. 178. No 4. P. 435-442.
16. Schaart G., Hesselink R.P., Keizer H.A. et al. A modified PAS stain combined with immunofluorescence for quantitative analyses of glycogen in muscle sections//Histochem. Cell Biol. 2004. Aug. V. 122. No 2. P. 161-169.
17. Winder W.W. Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle//J. Appl. Physiol. 2001. V. 91. P. 1017-1028.
18. Zong H., Ren J.M., Young L.H. et al. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation//Proc. Natl. Acad. Sci. USA. 2002. V. 99. No 25. P. 15983-15987.