Isoniazid toxicity presenting as status epilepticus and severe metabolic acidosis

Journal of Association of Physicians of India

Volumn 57, Issue JAN., 2009, Pages 70-71

  Gokhale, Yojana A ^a   Vaidya, Meghna S ^a   Mehta, A D ^a   Rathod, N N ^a  

^a LOKMANYA TILAK MUNICIPAL MEDICAL COLLEGE AND GENERAL HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BUFFER; ISONIAZID; MANNITOL; OSMOTIC DIURETIC AGENT; PYRIDOXINE; TUBERCULOSTATIC AGENT; VITAMIN B COMPLEX;

ACIDOSIS; ADULT; ARTICLE; CASE REPORT; CHEMICALLY INDUCED DISORDER; EPILEPTIC STATE; FEMALE; HUMAN; CHEMICALLY INDUCED; STATUS EPILEPTICUS;

ACIDOSIS; ADULT; ANTITUBERCULAR AGENTS; BICARBONATES; BUFFERS; DIURETICS, OSMOTIC; FEMALE; HUMANS; ISONIAZID; MANNITOL; PYRIDOXINE; STATUS EPILEPTICUS; VITAMIN B COMPLEX;

EID: 58849123271     PISSN: 00045772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Weber WW, Hein DW. Clinical Pharmacokinetics of Isoniazide. Clin Pharmacol 1979;4:401.
2. Holtz P, Parm D. Pharmacological aspects of vitamin B-6. Pharm Rev 1964;16:113-78.
3. Holdiness MR. Neurological manifestations and toxicities of the antituberculous drugs - A Review. Med toxicol 1987;2:33-51.
4. Hankins DG, Saxena K, Faville RJ. Profound acidosis caused by isoniazide ingestion. Am J E merg Med 1987;5:165-66.
5. Sievers ML, Herrier RN. Treatment of acute isoniazide toxicity. Am J Hosp Pharmacol 1975;32:202-6.