메뉴 건너뛰기




Volumn 15, Issue 1, 2009, Pages 72-79

Reversal of liver fibrosis

Author keywords

Antifibrotic; Cirrhosis; Fibrogenesis; Liver fibrosis

Indexed keywords

ALPHA TOCOPHEROL; ANTIFIBROTIC AGENT; ANTIOXIDANT; DELTA INTERFERON; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; FLAVANOID; INTERFERON; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; QUERCETIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 58849106702     PISSN: 13193767     EISSN: 19984049     Source Type: Journal    
DOI: 10.4103/1319-3767.45072     Document Type: Review
Times cited : (99)

References (97)
  • 2
    • 0001520008 scopus 로고
    • Hepatic lipocytes: The principal collagen-producing cells of normal rat liver
    • Friedman SL, Roll FJ, Boyles J, Bisslell DM. Hepatic lipocytes: The principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci 1985;82:8681-5.
    • (1985) Proc Natl Acad Sci , vol.82 , pp. 8681-8685
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3    Bisslell, D.M.4
  • 4
    • 0025359751 scopus 로고
    • Structure of the extracellular matrix in normal and fibrotic liver: Collagens and glycoproteins
    • Schuppan D. Structure of the extracellular matrix in normal and fibrotic liver: Collagens and glycoproteins. Semin Liver Dis 1990;10:1-10.
    • (1990) Semin Liver Dis , vol.10 , pp. 1-10
    • Schuppan, D.1
  • 5
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50.
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 6
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis-from bench to bedside
    • Friedman SL. Liver fibrosis-from bench to bedside. J Hepatol 2003;38:S38-53.
    • (2003) J Hepatol , vol.38
    • Friedman, S.L.1
  • 7
    • 0037371468 scopus 로고    scopus 로고
    • Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal
    • Bataller R, North KE, Brenner DA, Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal. Hepatology 2003;37:493-503.
    • (2003) Hepatology , vol.37 , pp. 493-503
    • Bataller, R.1    North, K.E.2    Brenner, D.A.3
  • 10
    • 0036829856 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and hepatitis C in the United States
    • El-Serag HB. Hepatocellular carcinoma and hepatitis C in the United States. Hepatology 2002;36:S74-83.
    • (2002) Hepatology , vol.36
    • El-Serag, H.B.1
  • 11
    • 3543098600 scopus 로고    scopus 로고
    • Liver fibrosis-from the bench to clinical targets
    • Pinzani M, Rombouts K. Liver fibrosis-from the bench to clinical targets. Dig Liver Dis 2004;36:231-42.
    • (2004) Dig Liver Dis , vol.36 , pp. 231-242
    • Pinzani, M.1    Rombouts, K.2
  • 12
    • 48349147074 scopus 로고    scopus 로고
    • The role of adipokines in liver fibrosis
    • Bertolani C, Marra F. The role of adipokines in liver fibrosis. Pathophysiology 2008;15:91-101.
    • (2008) Pathophysiology , vol.15 , pp. 91-101
    • Bertolani, C.1    Marra, F.2
  • 14
    • 34447317835 scopus 로고    scopus 로고
    • Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells
    • Novo E, Cannito S, Zamara E, Valfrè di Bonzo L, Caligiuri A, Cravanzola C, et al. Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells. Am J Pathol 2007;170:1942-53.
    • (2007) Am J Pathol , vol.170 , pp. 1942-1953
    • Novo, E.1    Cannito, S.2    Zamara, E.3    Valfrè di Bonzo, L.4    Caligiuri, A.5    Cravanzola, C.6
  • 15
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signalling in hepatic stellate cells
    • Pinzani M, Marra F. Cytokine receptors and signalling in hepatic stellate cells. Sem Liv Dis 2001;21:397-416.
    • (2001) Sem Liv Dis , vol.21 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 16
    • 0032857478 scopus 로고    scopus 로고
    • Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary fibrosis
    • Rosmorduc O, Wendum D, Corpechot C, Galy B, Sebbagh N, Raleigh J et al. Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary fibrosis. Am J Pathol 1999;155:1065-73
    • (1999) Am J Pathol , vol.155 , pp. 1065-1073
    • Rosmorduc, O.1    Wendum, D.2    Corpechot, C.3    Galy, B.4    Sebbagh, N.5    Raleigh, J.6
  • 17
    • 0036234428 scopus 로고    scopus 로고
    • Hypoxia - induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis
    • Corpechot C, Barbu V, Wendum D, Kinnman N, Rey C, Poupon R, et al. Hypoxia - induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology 2002;35:1010-21.
    • (2002) Hepatology , vol.35 , pp. 1010-1021
    • Corpechot, C.1    Barbu, V.2    Wendum, D.3    Kinnman, N.4    Rey, C.5    Poupon, R.6
  • 18
    • 37749049919 scopus 로고    scopus 로고
    • Antiangiogenic treatment with Sunitinib ameliorated inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats
    • Tugues S, Fernandez-Varo G, Muñoz-Luque J, Ros J, Arroyo V, Rodes J, et al. Antiangiogenic treatment with Sunitinib ameliorated inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology 2007;46:1919-26.
    • (2007) Hepatology , vol.46 , pp. 1919-1926
    • Tugues, S.1    Fernandez-Varo, G.2    Muñoz-Luque, J.3    Ros, J.4    Arroyo, V.5    Rodes, J.6
  • 19
    • 0034869459 scopus 로고    scopus 로고
    • Oxidative stress-related molecules and liver fibrosis
    • Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol 2001;35:297-306.
    • (2001) J Hepatol , vol.35 , pp. 297-306
    • Parola, M.1    Robino, G.2
  • 20
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
    • Tilg H, Hotamisligil GS. Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 2006;131:934-45.
    • (2006) Gastroenterology , vol.131 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 22
    • 0347949728 scopus 로고    scopus 로고
    • Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells
    • Zamara E, Novo E, Marra F, Gentilini A, Romanelli RG, Caligiuri A, et al. Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells. J Hepatol 2004;40:60-8.
    • (2004) J Hepatol , vol.40 , pp. 60-68
    • Zamara, E.1    Novo, E.2    Marra, F.3    Gentilini, A.4    Romanelli, R.G.5    Caligiuri, A.6
  • 23
    • 33745739887 scopus 로고    scopus 로고
    • NADPH oxidase in the liver: Defensive, offensive, or fibrogenic?
    • De Minicis S, Bataller R, Brenner DA. NADPH oxidase in the liver: Defensive, offensive, or fibrogenic? Gastroenterology 2006;131:272-5.
    • (2006) Gastroenterology , vol.131 , pp. 272-275
    • De Minicis, S.1    Bataller, R.2    Brenner, D.A.3
  • 24
    • 33845927120 scopus 로고    scopus 로고
    • Alcohol, oxidative stress and free radical damage
    • Albano E. Alcohol, oxidative stress and free radical damage. Proc Nutr Soc 2006;65:278-90.
    • (2006) Proc Nutr Soc , vol.65 , pp. 278-290
    • Albano, E.1
  • 25
    • 1942470986 scopus 로고    scopus 로고
    • Cirrhosis reversal: A duel between dogma and myth
    • Desmet VJ, Roskams T. Cirrhosis reversal: A duel between dogma and myth. J Hepatol 2004;40:860-7.
    • (2004) J Hepatol , vol.40 , pp. 860-867
    • Desmet, V.J.1    Roskams, T.2
  • 26
    • 3543098600 scopus 로고    scopus 로고
    • Liver fibrosis-from the bench to clinical targets
    • Pinzani M, Rombouts K. Liver fibrosis-from the bench to clinical targets. Dig Liver Dis 2004;36:231-42.
    • (2004) Dig Liver Dis , vol.36 , pp. 231-242
    • Pinzani, M.1    Rombouts, K.2
  • 27
    • 34247334927 scopus 로고    scopus 로고
    • Biliary epithelial-mesenchymal transition in post transplantation recurrence of primary biliary cirrhosis
    • Robertson H, Kirby JA, Yip WW, Jones DEJ, Burt AD. Biliary epithelial-mesenchymal transition in post transplantation recurrence of primary biliary cirrhosis. Hepatology 2007;45:977-81.
    • (2007) Hepatology , vol.45 , pp. 977-981
    • Robertson, H.1    Kirby, J.A.2    Yip, W.W.3    Jones, D.E.J.4    Burt, A.D.5
  • 29
    • 4043062139 scopus 로고    scopus 로고
    • Review article: The evolving role of liver biopsy
    • Campbell MS, Reddy KR. Review article: The evolving role of liver biopsy. Aliment Pharmacol Ther 2004;20:249-59.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 249-259
    • Campbell, M.S.1    Reddy, K.R.2
  • 30
    • 0019813866 scopus 로고
    • Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
    • Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981;1:431-5.
    • (1981) Hepatology , vol.1 , pp. 431-435
    • Knodell, R.G.1    Ishak, K.G.2    Black, W.C.3    Chen, T.S.4    Craig, R.5    Kaplowitz, N.6
  • 32
    • 0033962008 scopus 로고    scopus 로고
    • Grading and staging the histopathological lesions of chronic hepatitis: The Knodell histology activity index and beyond
    • Brunt EM. Grading and staging the histopathological lesions of chronic hepatitis: The Knodell histology activity index and beyond. Hepatology 2000;31:241-6.
    • (2000) Hepatology , vol.31 , pp. 241-246
    • Brunt, E.M.1
  • 33
    • 0036830347 scopus 로고    scopus 로고
    • The role of liver biopsy in chronic hepatitis C
    • Dienstag JL. The role of liver biopsy in chronic hepatitis C. Hepatology 2002;36:S152-60.
    • (2002) Hepatology , vol.36
    • Dienstag, J.L.1
  • 34
    • 0345017740 scopus 로고    scopus 로고
    • Sampling variability of liver fibrosis in chronic hepatitis C
    • Bedossa P, Dargere D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 2003;38:1449-57.
    • (2003) Hepatology , vol.38 , pp. 1449-1457
    • Bedossa, P.1    Dargere, D.2    Paradis, V.3
  • 35
    • 41349102478 scopus 로고    scopus 로고
    • Sampling error and intraobserver variability in liver biopsy in patients with chronic HCV infection
    • Regev A, Berho M, Jeffers LT, Milikowski C, Molina EG, Pyrsopoulos T, et al. Sampling error and intraobserver variability in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 2002;15:945-51.
    • (2002) Am J Gastroenterol , vol.15 , pp. 945-951
    • Regev, A.1    Berho, M.2    Jeffers, L.T.3    Milikowski, C.4    Molina, E.G.5    Pyrsopoulos, T.6
  • 36
    • 0037698889 scopus 로고    scopus 로고
    • Diagnosing fibrosis in hepatitis C: Is the pendulum swinging from biopsy to blood tests?
    • Afdhal NH. Diagnosing fibrosis in hepatitis C: Is the pendulum swinging from biopsy to blood tests? Hepatology 2003;37:972-4.
    • (2003) Hepatology , vol.37 , pp. 972-974
    • Afdhal, N.H.1
  • 37
    • 46749090413 scopus 로고    scopus 로고
    • Noninvasive monitoring of hepatitis C fibrosis progression
    • Kotlyar D, Blonski W, Rustgi V. Noninvasive monitoring of hepatitis C fibrosis progression. Clin Liver Dis 2008;12:557-71.
    • (2008) Clin Liver Dis , vol.12 , pp. 557-571
    • Kotlyar, D.1    Blonski, W.2    Rustgi, V.3
  • 38
    • 0035820265 scopus 로고    scopus 로고
    • Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: A prospective study
    • Imbert-Bismut F, Ratziu V, Pieroni L, Charlotte F, Benhamou Y, Poynard T, et al. Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: A prospective study. Lancet 2001;357:1069-75.
    • (2001) Lancet , vol.357 , pp. 1069-1075
    • Imbert-Bismut, F.1    Ratziu, V.2    Pieroni, L.3    Charlotte, F.4    Benhamou, Y.5    Poynard, T.6
  • 39
    • 0042265556 scopus 로고    scopus 로고
    • A simple non-invasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatits C
    • Wai CT, Greenson JK, Fontana RJ, Kalbfleisch JD, Marrero JA, Conjeevaram HS, et al. A simple non-invasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatits C. Hepatology 2003;38:518-26.
    • (2003) Hepatology , vol.38 , pp. 518-526
    • Wai, C.T.1    Greenson, J.K.2    Fontana, R.J.3    Kalbfleisch, J.D.4    Marrero, J.A.5    Conjeevaram, H.S.6
  • 40
    • 0036789328 scopus 로고    scopus 로고
    • Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model
    • Forns X, Ampurdanes S, Llovet JM, Aponte J, Quinto L, Martinez-Bauer E, et al. Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model. Hepatology 2002;36:986-92.
    • (2002) Hepatology , vol.36 , pp. 986-992
    • Forns, X.1    Ampurdanes, S.2    Llovet, J.M.3    Aponte, J.4    Quinto, L.5    Martinez-Bauer, E.6
  • 42
    • 9644272496 scopus 로고    scopus 로고
    • Evaluation of a panel of non-invasive serum markers to differentiate mild from moderate-to-advanced liver fibrosis in chronic hepatitis C patients
    • Patel K, Gordon SC, Jacobson I, Hézode C, Oh E, Smith KM, et al. Evaluation of a panel of non-invasive serum markers to differentiate mild from moderate-to-advanced liver fibrosis in chronic hepatitis C patients. J Hepatol 2004;41:935-42.
    • (2004) J Hepatol , vol.41 , pp. 935-942
    • Patel, K.1    Gordon, S.C.2    Jacobson, I.3    Hézode, C.4    Oh, E.5    Smith, K.M.6
  • 43
    • 32444451794 scopus 로고    scopus 로고
    • Performance of serum marker panels for liver fibrosis in chronic hepatitis C
    • Parkes J, Neil Guha I, Roderick P, Rosenberg W. Performance of serum marker panels for liver fibrosis in chronic hepatitis C. J Hepatol 2006;44:462-74.
    • (2006) J Hepatol , vol.44 , pp. 462-474
    • Parkes, J.1    Neil Guha, I.2    Roderick, P.3    Rosenberg, W.4
  • 44
    • 0036906034 scopus 로고    scopus 로고
    • Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: Longitudinal validation in a randomized trial
    • Poynard T, Imbert-Bismut F, Ratziu V, Chevret S, Jardel C, Moussalli J, et al. Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: Longitudinal validation in a randomized trial. J Viral Hepat 2002;9:128-33.
    • (2002) J Viral Hepat , vol.9 , pp. 128-133
    • Poynard, T.1    Imbert-Bismut, F.2    Ratziu, V.3    Chevret, S.4    Jardel, C.5    Moussalli, J.6
  • 45
    • 0042766810 scopus 로고    scopus 로고
    • Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin
    • Poynard T, McHutchison J, Manns M, Myers RP, Albrecht J. Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin. Hepatology 2003;38:481-92.
    • (2003) Hepatology , vol.38 , pp. 481-492
    • Poynard, T.1    McHutchison, J.2    Manns, M.3    Myers, R.P.4    Albrecht, J.5
  • 46
    • 54349094061 scopus 로고    scopus 로고
    • Why, who and how should perform liver biopsy in chronic liver diseases
    • Sporea I, Popescu A, Sirli R. Why, who and how should perform liver biopsy in chronic liver diseases. World J Gastroenterol 2008;14:3396-402.
    • (2008) World J Gastroenterol , vol.14 , pp. 3396-3402
    • Sporea, I.1    Popescu, A.2    Sirli, R.3
  • 47
    • 11144328418 scopus 로고    scopus 로고
    • Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C
    • Ziol M, Handra-Luca A, Kettaneh A, Christidis C, Mal F, Kazemi F, et al. Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005;41:48-54.
    • (2005) Hepatology , vol.41 , pp. 48-54
    • Ziol, M.1    Handra-Luca, A.2    Kettaneh, A.3    Christidis, C.4    Mal, F.5    Kazemi, F.6
  • 49
    • 35448989237 scopus 로고    scopus 로고
    • Fibro-test and FibroScan for the prediction of hepatitis C-related fibrosis: A systematic review of diagnostic test accuracy
    • Shaheen A, Wan A, Myers RP. Fibro-test and FibroScan for the prediction of hepatitis C-related fibrosis: A systematic review of diagnostic test accuracy. Am J Gastroenterol 2007;102:2589-600.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2589-2600
    • Shaheen, A.1    Wan, A.2    Myers, R.P.3
  • 50
    • 0014876077 scopus 로고
    • Hepatic fibrosis: Correlation of biologic and morphologic investigations
    • Popper H, Udenfriend S. Hepatic fibrosis: Correlation of biologic and morphologic investigations. Am J Med 1970;49:707-21.
    • (1970) Am J Med , vol.49 , pp. 707-721
    • Popper, H.1    Udenfriend, S.2
  • 51
    • 0018558974 scopus 로고
    • Cirrhosis of the liver: A reversible disease?
    • Perez-Tamayo R. Cirrhosis of the liver: A reversible disease? Pathol Ann 1979;14:183-213.
    • (1979) Pathol Ann , vol.14 , pp. 183-213
    • Perez-Tamayo, R.1
  • 52
    • 0030692704 scopus 로고    scopus 로고
    • Reversibility of hepatic fibrosis in autoimmune hepatitis
    • Dufour JF, DeLellis R, Kaplan MM. Reversibility of hepatic fibrosis in autoimmune hepatitis. Ann Intern Med 1997;127:981-5.
    • (1997) Ann Intern Med , vol.127 , pp. 981-985
    • Dufour, J.F.1    DeLellis, R.2    Kaplan, M.M.3
  • 53
    • 0035825721 scopus 로고    scopus 로고
    • Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct
    • Hammel P, Couvelard A, O'Toole D, Ratouis A, Sauvanet A, Flejou JF, et al. Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct. N Engl J Med 2001;344:418-23.
    • (2001) N Engl J Med , vol.344 , pp. 418-423
    • Hammel, P.1    Couvelard, A.2    O'Toole, D.3    Ratouis, A.4    Sauvanet, A.5    Flejou, J.F.6
  • 54
    • 0037035540 scopus 로고    scopus 로고
    • Reversibility of cirrhosis in patients cured of thalassemia by bone marrow transplantation
    • Muretto P, Angelucci E, Lucarelli G. Reversibility of cirrhosis in patients cured of thalassemia by bone marrow transplantation. Ann Intern Med 2002;136:667-72.
    • (2002) Ann Intern Med , vol.136 , pp. 667-672
    • Muretto, P.1    Angelucci, E.2    Lucarelli, G.3
  • 55
    • 2542546652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss
    • Dixon JB, Bhathal PS, Hughes NR, O'Brien PE. Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss. Hepatology 2004;39:1647-54.
    • (2004) Hepatology , vol.39 , pp. 1647-1654
    • Dixon, J.B.1    Bhathal, P.S.2    Hughes, N.R.3    O'Brien, P.E.4
  • 56
    • 0348047323 scopus 로고    scopus 로고
    • Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis
    • Kral JG, Thung SN, Biron S, Hould FS, Lebel S, Marceau S, et al. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery 2004;135:48-58.
    • (2004) Surgery , vol.135 , pp. 48-58
    • Kral, J.G.1    Thung, S.N.2    Biron, S.3    Hould, F.S.4    Lebel, S.5    Marceau, S.6
  • 57
    • 0035742752 scopus 로고    scopus 로고
    • Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B
    • Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burkhardt E, et al. Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol 2001;35:749-55.
    • (2001) J Hepatol , vol.35 , pp. 749-755
    • Kweon, Y.O.1    Goodman, Z.D.2    Dienstag, J.L.3    Schiff, E.R.4    Brown, N.A.5    Burkhardt, E.6
  • 58
    • 0030933395 scopus 로고    scopus 로고
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997;349:825-32.
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997;349:825-32.
  • 59
    • 17144455384 scopus 로고    scopus 로고
    • Histological improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy
    • Shiratori Y, Imazeki F, Moriyama M, Yano M, Arakawa Y, Yokosuka O, et al. Histological improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med 2000;132:517-24.
    • (2000) Ann Intern Med , vol.132 , pp. 517-524
    • Shiratori, Y.1    Imazeki, F.2    Moriyama, M.3    Yano, M.4    Arakawa, Y.5    Yokosuka, O.6
  • 60
    • 0035742752 scopus 로고    scopus 로고
    • Decreasing fibrogenesis: An immunoistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B
    • Kweon YO, Goodman ZD, Dienstag JL, Shiff ER, Brown NA, Burkardt E, et al. Decreasing fibrogenesis: An immunoistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol 2001;35:749-55.
    • (2001) J Hepatol , vol.35 , pp. 749-755
    • Kweon, Y.O.1    Goodman, Z.D.2    Dienstag, J.L.3    Shiff, E.R.4    Brown, N.A.5    Burkardt, E.6
  • 62
    • 0036242165 scopus 로고    scopus 로고
    • Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
    • Poynard T, McHutchison J, Manns M, Trepo C, Lindsay K, Goodman Z, et al. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002;122:1303-13.
    • (2002) Gastroenterology , vol.122 , pp. 1303-1313
    • Poynard, T.1    McHutchison, J.2    Manns, M.3    Trepo, C.4    Lindsay, K.5    Goodman, Z.6
  • 63
    • 2942568157 scopus 로고    scopus 로고
    • Long-term benefit of interferon alpha therapy of chronic hepatitis D: Regression of advanced hepatic fibrosis
    • Farci P, Roskams T, Chessa L, Peddis G, Mazzoleni AP, Scioscia R, et al. Long-term benefit of interferon alpha therapy of chronic hepatitis D: Regression of advanced hepatic fibrosis. Gastroenterology 2004;126:1740-9.
    • (2004) Gastroenterology , vol.126 , pp. 1740-1749
    • Farci, P.1    Roskams, T.2    Chessa, L.3    Peddis, G.4    Mazzoleni, A.P.5    Scioscia, R.6
  • 65
    • 34548806374 scopus 로고    scopus 로고
    • Hong Kong Liver Fibrosis Study. Sustained disease remission after spontaneous HBeAg seroconversion is associated with reduction in fibrosis progression in chronic hepatitis B Chinese patients
    • Hui CK, Leung N, Shek TW, Yao H, Lee WK, Lai JY, et al. Hong Kong Liver Fibrosis Study. Sustained disease remission after spontaneous HBeAg seroconversion is associated with reduction in fibrosis progression in chronic hepatitis B Chinese patients. Hepatology 2007;46:690-8.
    • (2007) Hepatology , vol.46 , pp. 690-698
    • Hui, C.K.1    Leung, N.2    Shek, T.W.3    Yao, H.4    Lee, W.K.5    Lai, J.Y.6
  • 66
    • 14844337493 scopus 로고    scopus 로고
    • Long-term management of alcoholic liver disease
    • Wakim-Fleming J, Mullen KD. Long-term management of alcoholic liver disease. Clin Liver Dis 2005;9:135-49.
    • (2005) Clin Liver Dis , vol.9 , pp. 135-149
    • Wakim-Fleming, J.1    Mullen, K.D.2
  • 67
    • 0348047323 scopus 로고    scopus 로고
    • Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis
    • Kral JG, Thung SN, Biron S, Hould FS, Lebel S, Marceau S, et al. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery 2004;135:48-58.
    • (2004) Surgery , vol.135 , pp. 48-58
    • Kral, J.G.1    Thung, S.N.2    Biron, S.3    Hould, F.S.4    Lebel, S.5    Marceau, S.6
  • 68
    • 0041664940 scopus 로고    scopus 로고
    • Reversal of cirrhosis: Evidence based medicine?
    • Desmet VJ, Roskams T. Reversal of cirrhosis: Evidence based medicine? Gastroenterology 2003;125:629-30.
    • (2003) Gastroenterology , vol.125 , pp. 629-630
    • Desmet, V.J.1    Roskams, T.2
  • 69
    • 0033749190 scopus 로고    scopus 로고
    • Regression of human cirrhosis: Morphologic features and the genesis of incomplete septal cirrhosis
    • Wanless IR, Nakashima E, Sherman M. Regression of human cirrhosis: Morphologic features and the genesis of incomplete septal cirrhosis. Arch Pathol Lab Med 2000;124:1599-607.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 1599-1607
    • Wanless, I.R.1    Nakashima, E.2    Sherman, M.3
  • 70
    • 0037383894 scopus 로고    scopus 로고
    • Milestones in liver disease: Scoring chronic hepatitis
    • Desmet VJ. Milestones in liver disease: Scoring chronic hepatitis. J Hepatol 2003;38:382-6.
    • (2003) J Hepatol , vol.38 , pp. 382-386
    • Desmet, V.J.1
  • 71
    • 0007179304 scopus 로고
    • What are the major types of hepatic cirrhosis?
    • Ingelfinger F, Relman A, Finland M, editors, Philadelphia, PA: WB Saunders;
    • Popper H. What are the major types of hepatic cirrhosis? In: Ingelfinger F, Relman A, Finland M, editors. Controversies in internal medicine. Philadelphia, PA: WB Saunders; 1966. p. 233-43.
    • (1966) Controversies in internal medicine , pp. 233-243
    • Popper, H.1
  • 72
    • 0021055147 scopus 로고
    • The Copenhagen study group for liver disease: Conversion of micronodular into macronodular cirrhosis
    • Fauerholdt L, Schlichting P, Christensen E, Poulsen H, Tygstrup N, Juhl E. The Copenhagen study group for liver disease: Conversion of micronodular into macronodular cirrhosis. Hepatology 1983;3: 928-31.
    • (1983) Hepatology , vol.3 , pp. 928-931
    • Fauerholdt, L.1    Schlichting, P.2    Christensen, E.3    Poulsen, H.4    Tygstrup, N.5    Juhl, E.6
  • 73
    • 0037223652 scopus 로고    scopus 로고
    • United network for organ sharing liver disease severity score committee: Model for end-stage liver disease (MELD) and allocation of donor livers
    • Wiesner R, Edwards E, Freeman R, Harper A, Kim R, Kamath P, et al. United network for organ sharing liver disease severity score committee: Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 2003;124:91-6.
    • (2003) Gastroenterology , vol.124 , pp. 91-96
    • Wiesner, R.1    Edwards, E.2    Freeman, R.3    Harper, A.4    Kim, R.5    Kamath, P.6
  • 74
    • 24044506279 scopus 로고    scopus 로고
    • Is cirrhosis an inevitable consequence of chronic hepatitis C infection?
    • Seef LB, Lie BA. Is cirrhosis an inevitable consequence of chronic hepatitis C infection? Clin Gastroenterol Hepatol 2005;3:840-2.
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 840-842
    • Seef, L.B.1    Lie, B.A.2
  • 75
    • 0037129380 scopus 로고    scopus 로고
    • Non alcoholic fatty liver disease
    • Angulo P. Non alcoholic fatty liver disease. N Engl J Med 2002;346:1221-31.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 76
    • 34247394547 scopus 로고    scopus 로고
    • Progression of fibrosis in advanced chronic hepatitis C: Evaluation by morphometric image analysis
    • Goodman ZD, Becker RL, Pockros PJ, Afdhal NH. Progression of fibrosis in advanced chronic hepatitis C: Evaluation by morphometric image analysis. Hepatology 2007;45:886-94.
    • (2007) Hepatology , vol.45 , pp. 886-894
    • Goodman, Z.D.1    Becker, R.L.2    Pockros, P.J.3    Afdhal, N.H.4
  • 77
    • 33750323347 scopus 로고    scopus 로고
    • Measurement of portal pressure and its role in the management of chronic liver disease: Prognosis in Patients with Cirrhosis
    • Bosch J, Garcia-Pagan JC, Berzigotti A, Abraldes Jl. Measurement of portal pressure and its role in the management of chronic liver disease: Prognosis in Patients with Cirrhosis. Sem Liver Dis 2006;26:348-62.
    • (2006) Sem Liver Dis , vol.26 , pp. 348-362
    • Bosch, J.1    Garcia-Pagan, J.C.2    Berzigotti, A.3    Abraldes, J.4
  • 79
    • 39049101883 scopus 로고    scopus 로고
    • Technology insight: Noninvasive assessment of liver fibrosis by biochemical scores and elastography
    • Pinzani M, Vizzutti M, Arena U, Marra F. Technology insight: Noninvasive assessment of liver fibrosis by biochemical scores and elastography. Nat Clin Pract Gastroenterol Hepatol 2008;5:95-106.
    • (2008) Nat Clin Pract Gastroenterol Hepatol , vol.5 , pp. 95-106
    • Pinzani, M.1    Vizzutti, M.2    Arena, U.3    Marra, F.4
  • 80
    • 40949145677 scopus 로고    scopus 로고
    • Relationship of serum markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C
    • Fontana RJ, Goodman ZD, Dienstag J, Bonkowsky HL, Naishadham D, Sterling RK, et al. Relationship of serum markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C. Hepatology 2008;47:789-98.
    • (2008) Hepatology , vol.47 , pp. 789-798
    • Fontana, R.J.1    Goodman, Z.D.2    Dienstag, J.3    Bonkowsky, H.L.4    Naishadham, D.5    Sterling, R.K.6
  • 81
    • 34248680523 scopus 로고    scopus 로고
    • Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis
    • Vizzutti F, Arena U, Romanelli RG, Rega L, Foschi M, Colagrande S, et al. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology 2007;45:1290-7.
    • (2007) Hepatology , vol.45 , pp. 1290-1297
    • Vizzutti, F.1    Arena, U.2    Romanelli, R.G.3    Rega, L.4    Foschi, M.5    Colagrande, S.6
  • 82
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies
    • Friedman SL. The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies. N Engl J Med 1993;328:1828-35.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 83
    • 33845316462 scopus 로고    scopus 로고
    • New Therapies in hepatitis C virus and chronic liver disease: Antifibrotics
    • Rockey DC. New Therapies in hepatitis C virus and chronic liver disease: Antifibrotics. Clin Liver Dis 2006;10:881-900.
    • (2006) Clin Liver Dis , vol.10 , pp. 881-900
    • Rockey, D.C.1
  • 84
    • 0032410557 scopus 로고    scopus 로고
    • Regression of hepatic fibrosis in hepatitis C with long term interferon treatment
    • Dufour JF, DeLellis R, Kaplan MM. Regression of hepatic fibrosis in hepatitis C with long term interferon treatment. Dig Dis Sci 1998;43:2573.
    • (1998) Dig Dis Sci , vol.43 , pp. 2573
    • Dufour, J.F.1    DeLellis, R.2    Kaplan, M.M.3
  • 85
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, Tong MJ, Sievert W, Shiffman ML, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003;348:808-16.
    • (2003) N Engl J Med , vol.348 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3    Tong, M.J.4    Sievert, W.5    Shiffman, M.L.6
  • 86
    • 3543098600 scopus 로고    scopus 로고
    • Liver fibrosis: From the bench to clinical targets
    • Pinzani M, Rombouts K. Liver fibrosis: From the bench to clinical targets. Dig Liver Dis 2004;36:231-42.
    • (2004) Dig Liver Dis , vol.36 , pp. 231-242
    • Pinzani, M.1    Rombouts, K.2
  • 88
    • 0030854425 scopus 로고    scopus 로고
    • A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C
    • Houglum K, Venkataramani A, Lyche K, Chojkier M. A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C. Gastroenterology 1997;113:1069-73.
    • (1997) Gastroenterology , vol.113 , pp. 1069-1073
    • Houglum, K.1    Venkataramani, A.2    Lyche, K.3    Chojkier, M.4
  • 89
    • 0026670128 scopus 로고
    • Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis
    • Parola M, Leonarduzzi G, Biasi F, Albano E, Biocca ME, Poli G, et al. Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis. Hepatology 1992;16:1014-21.
    • (1992) Hepatology , vol.16 , pp. 1014-1021
    • Parola, M.1    Leonarduzzi, G.2    Biasi, F.3    Albano, E.4    Biocca, M.E.5    Poli, G.6
  • 90
    • 0028679641 scopus 로고
    • Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis
    • Rockey DC, Chung JJ. Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis. J Investig Med 1994;42:660-70.
    • (1994) J Investig Med , vol.42 , pp. 660-670
    • Rockey, D.C.1    Chung, J.J.2
  • 92
    • 0036893741 scopus 로고    scopus 로고
    • Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension
    • Croquet V, Moal F, Veal N, Wang J, Oberti F, Roux J, et al. Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension. J Hepatol 2002;37:773-80.
    • (2002) J Hepatol , vol.37 , pp. 773-780
    • Croquet, V.1    Moal, F.2    Veal, N.3    Wang, J.4    Oberti, F.5    Roux, J.6
  • 94
    • 0034849945 scopus 로고    scopus 로고
    • Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis
    • Paizis G, Gilbert RE, Cooper ME, Murthi P, Schembri JM, Wu LL, et al. Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis. J Hepatol 2001;35:376-85.
    • (2001) J Hepatol , vol.35 , pp. 376-385
    • Paizis, G.1    Gilbert, R.E.2    Cooper, M.E.3    Murthi, P.4    Schembri, J.M.5    Wu, L.L.6
  • 95
    • 0034120477 scopus 로고    scopus 로고
    • An oral endothelin: A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
    • Cho JJ, Hocher B, Herbst H, Jia JD, Ruehl M, Hahn EG, et al. An oral endothelin: A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology 2000;118:1169-78.
    • (2000) Gastroenterology , vol.118 , pp. 1169-1178
    • Cho, J.J.1    Hocher, B.2    Herbst, H.3    Jia, J.D.4    Ruehl, M.5    Hahn, E.G.6
  • 96
    • 0036082703 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
    • Galli A, Crabb DW, Ceni E, Salzano R, Mello T, Svegliati-Baroni G, et al. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 2002;122:1924-40.
    • (2002) Gastroenterology , vol.122 , pp. 1924-1940
    • Galli, A.1    Crabb, D.W.2    Ceni, E.3    Salzano, R.4    Mello, T.5    Svegliati-Baroni, G.6
  • 97
    • 0033855572 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
    • Marra F, Efsen E, Romanelli RG, Caligiuri A, Pastacaldi S, Batignani G, et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000;119:466-78.
    • (2000) Gastroenterology , vol.119 , pp. 466-478
    • Marra, F.1    Efsen, E.2    Romanelli, R.G.3    Caligiuri, A.4    Pastacaldi, S.5    Batignani, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.