Virus vaccines and children with asthma

Current Opinion in Allergy and Clinical Immunology

Volumn 9, Issue 1, 2009, Pages 44-49

  Anderson, Mark ^a   Carroll, Will ^a  

^a DERBYSHIRE CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

Asthma; Influenza; Respiratory syncytial virus; Rhinovirus; Vaccine

Indexed keywords

BCG VACCINE; INFLUENZA VACCINE; MEASLES VACCINE; PALIVIZUMAB; PERTUSSIS VACCINE; VIRUS VACCINE; WART VIRUS VACCINE;

ASTHMA; ATOPY; CLINICAL FEATURE; CLINICAL TRIAL; DISEASE ASSOCIATION; DISEASE EXACERBATION; HUMAN; IMMUNIZATION; INCIDENCE; INFLUENZA; MEASLES; MORBIDITY; NONHUMAN; PATHOGENESIS; PERTUSSIS; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; RHINOVIRUS INFECTION; RISK FACTOR; VIRUS INFECTION;

ADOLESCENT; ASTHMA; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; HUMANS; IMMUNIZATION PROGRAMS; INFANT; INFANT, NEWBORN; RESPIRATORY TRACT INFECTIONS; RISK FACTORS; VACCINATION; VIRAL VACCINES;

EID: 58849103875     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e32831f8ef3     Document Type: Review

References (67)

1. Strachan DP. Hay fever, hygiene, and household size. BMJ 1989; 299:1259- 1260.
2. Minor TE, Dick EC, DeMeo AN, et al. Viruses as precipitants of asthmatic attacks in children. JAMA 1974; 227:292-298.
3. Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995; 310:1225-1229.
4. Rawlinson WD, Waliuzzaman Z, Carter IW, et al. Asthma exacerbations in children associated with rhinovirus but not human metapneumovirus infection. J Infect Dis 2003; 187:1314-1318.
5. Heininger U. The success of immunization: shovelling its own grave? Vaccine 2004; 22:2071-2072.
6. Breman JG, Arita I. The confirmation and maintenance of smallpox eradication. N Engl J Med 1980; 303:1263-1273.
7. Theiler M, Smith HH. The use of yellow fever virus modified by in vitro cultivation for human immunization. J Exp Med 1937; 65:787-800.
8. Dawar M, Deeks S, Dobson S. Human papillomavirus vaccines launch a new era in cervical cancer prevention. CMAJ 2007; 177:456-461.
9. Holt PG, Sly PD. Emerging concepts of T-cell regulation in asthma and allergy: new rules for an old game. Allergy Clin Immunol Int 2003; 15:255- 262.
10. Williams T, Jones C, Miles E, et al. Fetal and neonatal IL-13 production during pregnancy and at birth and subsequent development of atopic symptoms. J Allergy Clin Immunol 2000; 105:951-959.
11. Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today 1993; 14:353-356.
12. Björkstén B. Allergy priming early in life. Lancet 1999; 353:167-168.
13. Odent MR, Culpin EE, Kimmel T. Pertussis vaccination and asthma: is there a link? JAMA 1994; 272:592-593.
14. Farooqui IS, Hopkin JM. Early childhood infection and atopic disorder. Thorax 1998; 53:927-932.
15. Gruber C, Meinlschmidt G, Bergmann R, et al. Is early BCG vaccination associated with less atopic disease? An epidemiological study in German preschool children with different ethnic backgrounds. Pediatr Allergy Immunol 2002; 13:177-181.
16. DeStefano F, Gu D, Kramarz P, et al. Childhood vaccinations and risk of asthma. Pediatr Infect Dis J 2002; 21:498-504.
17. Bernsen RM, de Jongste JC, van der Wouden JC. Lower risk of atopic disorders in whole cell pertussis-vaccinated children. Eur Respir J 2003; 22:962-964.
18. Nilsson L, Kjellman Nl, Bjorkstein B. Allergic disease at the age of 7 years after pertussis vaccination in infancy: results from the follow-up of a randomized controlled trial of 3 vaccines. Arch Pediatr Adolesc Med 2003; 157:1184- 1189.
19. Mommers M, Weishoff-Houben M, Swaen GM, et al. Infant immunization and the occurrence of atopic disease in Dutch and German children: a nested case-control study. Pediatr Pulmonol 2004; 38:329-334.
20. Maitra A, Sheriff A, Griffiths M, Henderson J, for the Avon Longitudinal Study of Parents and Children Study team. Pertussis vaccination in infancy and asthma or allergy in later childhood: birth cohort study. BMJ 2004; 328:925- 926.
21. Balicer RD, Grotto I, Mimouni M, Mimouni D. Is childhoood vaccination associated with asthma? A meta-analysis of observational studies. Pediatrics 2007; 120:e1269-e1277. An excellent review of the current evidence connecting childhood immunization with subsequent asthma risk.
22. Shaheen SO, Aaby P, Hall AJ, et al. Measles and atopy in Guinea-Bissau. Lancet 1996; 347:1792-1796.
23. Matricardi PM, Rosmini F, Ferrigno L, et al. Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ 1997; 314:999-1003.
24. Matricardi PM, Rosmini F, Panetta V, et al. Hay fever and asthma in relation to markers of infection in the United States. J Allergy Clin Immunol 2002; 110:381-387.
25. Williams LK, Peterson EL, Ownby DR, et al. The relationship between early fever and allergic sensitization at age 6 to 7 years. J Allergy Clin Immunol 2004; 113:291-296.
26. Bodner C, Anderson WJ, Reid TS, et al. Childhood exposure to infection and risk of adult onset wheeze and atopy. Thorax 2000; 55:383-387.
27. Cullinan P, Harris JM, Newman Taylor AJ, et al. Can early infection explain the sibling effect in adult atopy? Eur Respir J 2003; 22:956-961.
28. Nafstad P, Brunekreef B, Skrondal A, et al. Early respiratory infections, asthma, and allergy: 10-year follow-up of the Oslo birth cohort. Pediatrics 2005; 116:e255-e262.
29. Harris JM, Mills P, White C, et al. Recorded infections and antibiotics in early life: associations with allergy in UK children and their parents. Thorax 2007; 62:631-637. An interesting study demonstrating a lack of association between early infections or antibiotic use and development of atopy.
30. Anderson H, Poloniecki J, Strachan D, et al. Immunization and symptoms of atopic disease in children: results from the international study of asthma and allergies in childhood. Am J Public Health 2001; 91:1126-1129.
31. Wickens K, Crane J, Kemp T, et al. A case-control study of risk factors for asthma in New Zealand children. Aust N Z J Public Health 2001; 25:44-49.
32. Ward BJ, Griffin DE. Changes in cytokine production after measles virus vaccination: predominant production of IL-4 suggests induction of a Th2 response. Clin Immunol Immunopathol 1993; 67:171 -177.
33. Benke G, Abramson M, Raven J, et al. Aust N Z J Public Health 2004; 28:336-338.
34. Freymuth F, Vabret A, Brouard J, et al. Detection of viral, Chlamydia pneumoniae and Mycoplasma pneumoniae infections in exacerbations of asthma in children. J Clin Virol 1999; 13:131-139.
35. Thumerelle C, Deschildre A, Bouquillon C. Role of viruses and atypical bacteria in exacerbations of asthma in hospitalized children. Pediatr Pulmonol 2003; 35:75-82.
36. Khetsuriani N, Kazerouni NN, Erdman DD, et al. Prevalence of viral respiratory tract infections in children with asthma. J Allergy Clin Immunol 2007; 119:314-321. The latest study to demonstrate that rhinovirus is probably the most important viral cause of exacerbations in children with asthma.
37. Sigurs N, Bjarnason R, Sigurbergsson F, Kjellman B. Respiratory syncitial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 2000; 161:1501 -1507.
38. Sigurs N, Gustafsson PM, Bjarnason R, et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 2005; 171:137-141.
39. Stein RT, Sherrill D, Morgan WJ, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999; 354:541 - 545.
40. Harsten G, Prellner K, Löfgren B, et al. Serum antibodies against respiratory tract viruses: a prospective three-year follow-up from birth. J Laryngol Otol 1989; 103:904-908.
41. Welliver RC. RSV and chronic asthma. Lancet 1995; 346:789-790.
42. Elphick HE, Ritson S, Rigby AS, Everard ML. Phenotype of acute respiratory syncytial virus induced lower respiratory tract illness in infancy and subsequent morbidity. Acta Paediatr 2007; 96:307-309. This study subdivides the RSV infection phenotype into classical bronchiolitis (crepitations ± wheeze) and wheezy bronchitis (predominantly wheeze) and indicates that only the latter group is predisposed to development of asthma, suggesting that host factors are more important than RSV infection per se.
43. Mohapatra SS, Boyapalle S. Epidemiologic, experimental and clinical links between respiratory syncytial virus infection and asthma. Clin Microbiol Rev 2008; 21:495-504. Good overview of RSV infection and the experimental evidence linking it with later development of asthma.
44. Tourdot S, Mathie S, Hussell T, et al. Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization. Clin Exp Allergy 2008; 38:1016-1024.
45. Simoes E, Groothuis J, Carbonell-Estrany X, et al., for the Palivizumab Long Term Respiratory Outcomes Study group. Palivizumab prophylaxis, respiratory syncytial virus and subsequent recurrent wheezing. J Pediatr 2007; 151:34-42. Study demonstrating reduction in post-RSV wheezing in preterm infants following passive immunization with palivizumab.
46. Power UF. Respiratory syncytial virus (RSV) vaccines: two steps back for one leap forward. J Clin Virol 2008; 41:38-44. An excellent review of putative RSV vaccine targets and a discussion of why RSV is difficult to produce vaccines for.
47. Tang RS, Spate RR, Thompson MW, et al. Development of a PIV-vectored RSV vaccine: preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults. Vaccine 2008 [Epub ahead of print], doi: 10.1016/j.vaccine.2008.09.018.
48. Kotaneimi-Syrjanen A, Vainionpaa R, Reijonen TM, et al. Rhinovirus-induced wheezing in infancy: the first sign of childhood asthma? J Allergy Clin Immunol 2003; 111:66-71.
49. Lemanske RF, Jackson DJ, Gangnon RE, et al. Rhinovirus illnesses during infancy predict subsequent childhood wheezing. J Allergy Clin Immunol 2005; 116:571 -577.
50. Jackson DJ, Gangnon RE, Evans MD, et al. Wheezing rhinovirus illnesses in early life predict asthma development in high risk children. Am J Respir Crit Care Med 2008; 178:667-672. The most recent study to demonstrate that viral wheeze in infancy caused by rhinovirus is a risk factor for subsequent asthma development with an OR of 10.
51. Atmar RL, Guy E, Guntupalli KK, et al. Respiratory tract viral infections in inner- city asthmatic adults. Arch Intern Med 1998; 158:2453-2459.
52. Rakes GP, Arrunda E, Ingram JM, et al. Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care: IgE and eosiniphil analysis. Am J Respir Crit Care Med 1999; 159:785-790.
53. Heymann PW, Carper HT, Murphy DD, et al. Viral infections in relation to age, atopy and season of admission among children hospitalized for wheezing. J Allergy Clin Immunol 2004; 114:239-247.
54. O'Brien MA, Uyeki TM, Shay DK, et al. Incidence of outpatient visits and hospitalizations related to influenza in infants and young children. Pediatrics 2004; 113:585-593.
55. Miller EK, Griffin MR, Edwards KM, et al., for the New Vaccine Surveillance Network. Influenza burden for children with asthma. Pediatrics 2008; 121:1-8. Observational study showing an increased risk of hospitalization with influenza in children with asthma.
56. Neuzil KM, Wright PF, Mitchel EF Jr, Griffin MR. The burden of influenza illness in children with asthma and other chronic medical conditions. J Pediatr 2000; 137:856-864.
57. Carroll W, Burkimsher R. Is there any evidence for influenza vaccination in children with asthma? Arch Dis Child 2007; 92:644-645. Evidence-based review of the benefit of influenza vaccination in children with asthma.
58. Bueving HJ, Bernsen RMD, de Jongste JC, et al. Influenza vaccination in children with asthma. Am J Respir Crit Care Med 2004; 269:488- 493.
59. Kramarz P, DeStefano F, Gargiullo PM, et al., for the Vaccine Safety Datalink Team. Does influenza vaccination prevent asthma exacerbations in children? J Pediatrics 2000; 138:306-310.
60. Smits AJ, Hak E, Stalman WAB, et al. Clinical effectiveness of conventional influenza vaccination in asthmatic children. Epidemiol Infect 2002; 128:205- 211.
61. Christy C, Aligne CA, Auinger P, et al. Effectiveness of influenza vaccine for the prevention of asthma exacerbations. Arch Dis Child 2004; 89: 734-735.
62. Eurich DT, Marrie TJ, Johnstone J, Majumdar SR. Mortality reduction with influenza vaccine in patients with pneumonia outside 'flu' season. Am J Respir Crit Care Med 2008; 178:527-533. Observational case-control study in the elderly showing that vaccine benefit on mortality can be attributed to 'healthy user effect' in which healthier people who tend to watch what they eat, exercise regularly and don't smoke are also the people who are most likely to comply with drug and vaccine regimens.
63. American Lung Association Asthma Clinical Research Centers. The safety of inactivated influenza vaccine in adults and children with asthma. N Engl J Med 2001; 345:1529-1536.
64. Department of Health. The influenza immunization programme. 2005. http://www.dh.gov.uk/assetRoot/04/11/65/17/04116517.pdf [Accessed 4 September 2008].
65. Centers for Disease Control and Prevention. Recommendation of the Public Health Service Advisory Committee on Immunization Practices: influenza vaccine, civilian use - 1966-67. MMWR Morb Mortal Wkly Rep 1966; 15:238-239.
66. Szilagyi PG, Holl JL, Rodewald LE, et al. Evaluation of New York State's Child Health Plus: children who have asthma. Pediatrics 2000; 105:719-727.
67. Heikkinen T, Järvinen A. The common cold. Lancet 2003; 361:51 -59.