Posttraumatic epilepsy: Treatable epileptogenesis

Epilepsia

Volumn 50, Issue SUPPL. 2, 2009, Pages 1-3

  Jensen, Frances E ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; APOPTOSIS INHIBITOR; CALCIUM CHANNEL BLOCKING AGENT; CASPASE INHIBITOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; ION CHANNEL; NEUROTRANSMITTER RECEPTOR; NEUROTROPHIC FACTOR;

CLINICAL FEATURE; CLINICAL TRIAL; COGNITIVE DEFECT; DIFFUSION TENSOR IMAGING; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; EDITORIAL; EPILEPTOGENESIS; GENE EXPRESSION; HUMAN; LATENT PERIOD; NERVE CELL NETWORK; NEUROIMAGING; NEUROPHYSIOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE; STEM CELL TRANSPLANTATION; TRAUMATIC BRAIN INJURY; TRAUMATIC EPILEPSY; ANIMAL; BRAIN; BRAIN INJURY; DISEASE MODEL; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; PATHOPHYSIOLOGY; PROGNOSIS;

ANIMALS; ANTICONVULSANTS; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSY, POST-TRAUMATIC; HUMANS; PROGNOSIS;

EID: 58849085451     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.02003.x     Document Type: Editorial

References (13)

1. Cornejo BJ, Mesches MH, Coultrap S, Browning MD, Benke TA 2007) A single episode of neonatal seizures permanently alters glutamatergic synapses. Ann Neurol 61 : 411 426.
2. Diaz-Arrastia R, Agostini MA, Madden CJ, Van Ness PC 2009) Posttraumatic epilepsy: The endophenotypes of a human model of epileptogenesis. Epilepsia 50 (Suppl. 2 14 20.
3. Dichter MA 2009) Posttraumatic epilepsy: The challenge of translating discoveries in the laboratory to pathways to a cure. Epilepsia 50 (Suppl. 2 41 45.
4. Dudek FE, Sutula TP 2007) Epileptogenesis in the dentate gyrus: a critical perspective. Prog Brain Res 163 : 755 773.
5. Lowenstein DH 2009) Epilepsy after head injury: An overview. Epilepsia 50 (Suppl. 2 4 9.
6. McNamara JO, Huang YZ, Leonard AS 2006) Molecular signaling mechanisms underlying epileptogenesis. Sci STKE 2006 : re12 [DOI: 10.1126/stke.3562006re12] .
7. Pitkänen A, Immonen RJ, Gröhn OHJ, Kharatishvili I 2009) From traumatic brain injury to posttraumatic epilepsy: What animal models tell us about the process and treatment options. Epilepsia 50 (Suppl. 2 21 29.
8. Prince DA, Parada I, Scalise K, Graber K, Jin X, Shen F 2009) Epilepsy following cortical injury: Cellular and molecular mechanisms as targets for potential prophylaxis. Epilepsia 50 (Suppl. 2 30 40.
9. Rakhade SN, Zhou C, Aujla PK, Fishman R, Sucher NJ, Jensen FE 2008) Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures. J Neurosci 28 : 7979 7990.
10. Scharfman HE 2007) The neurobiology of epilepsy. Curr Neurol Neurosci Rep 7 : 348 354.
11. Temkin NR 2009) Preventing and treating posttraumatic seizures: The human experience. Epilepsia 50 (Suppl. 2 10 13.
12. Vezzani A, Granata T 2005) Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 46 : 1724 1743.
13. Willmore LJ, Ueda Y 2008) Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate. Neurochem Res 11 September [Epub ahead of print].