Towards metformin prodrugs

Synthesis

Volumn , Issue 22, 2008, Pages 3619-3624

  Huttunen, Kristiina M ^a   Leppänen, Jukka ^a   Kemppainen, Eeva ^a   Palonen, Piia ^a   Rautio, Jarkko ^a   Järvinen, Tomi ^a   Vepsäläinen, Jouko ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Heterocycle; Metformin; Prodrug; Self immolative spacer group; Urethane

Indexed keywords

HETEROCYCLE; METFORMIN; PRODRUG; SELF-IMMOLATIVE SPACER GROUP; URETHANE;

1 CYANO 2 METHOXYGUANIDINE; 1 DIMETHYLLIMIDODICARBONIMIDIC DIAMIDE; 2,2 DIETHOXY N4,N4 DIMETHYL[1,3,5,2]TRIAZAPHOSPHININE 4,6 DIAMINE; 3 [3 (N,N DIMETHYLCARBAMIMIDOYL)GUANIDINO]PROPYL ACETATE; 4 (BROMOMETHYL) 1,3 PHENYLENE BIS (2,2 DIMETHYLPROPANOATE); 4 (HYDROXYMETHYL) 1,3 PHENYLENE BIS (2,2 DIMETHYLPROPANOATE); 4 [[3 (N,N DIMETHYLCARBAMIMIDOYL)GUANIDINO]METHYL] 3 HYDROXYPHENYL PIVALATE; 4 [[3 (N,N DIMETHYLCARBAMIMIDOYL)GUANIDINO]METHYL]PHENYL DIETHYULCARBAMATE; 4 [[3 (N,N DIMETHYLCARBAMIMIDOYL)GUANIDINO]METHYL]PHENYL OCTANOATE; 4 AMINO 6 DIMETHYLAMINO[1,3,5]TRIAZIN 2 OL; [(N',N' DIMETHYLCARBAMIMIDOYL)GUANIDINO] 4 PHENYL 1,3,2 DI OXAPHOSPHORAMIDATE; [(N',N' DIMETHYLGUANIDINO)IMINOMETHYL]CARBAMIC ACID 2,2,2 TRICHLOROETHYL ESTER; [(N',N' DIMETHYLGUANIDINO)IMINOMETHYL]CARBAMIC ACID BENZYL ESTER; [1,2,4]OXADIAZOLE 3,5 DIAMINE; METFORMIN; N1,N1 DIMETHYLCARBAMIMIDOYL N4 METHOXYGUANIDINE; PRODRUG; TERT BUTYL 4 [[3 (N,N DIMETHYLCARBAMIMIDOYL)GUANIDINO]METHYL]PHENYL CARBAMATE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 58849084559     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1083603     Document Type: Article

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