Synthesis and biodistribution of lipophilic and monocationic gallium radiopharmaceuticals derived from N,N′-bis(3-aminopropyl)-N,N′-dimethylethylenediamine: potential agents for PET myocardial imaging with 68Ga

Nuclear Medicine and Biology

Volumn 36, Issue 1, 2009, Pages 39-45

  Hsiao, Yui May ^a   Mathias, Carla J ^a   Wey, Shiaw Pyng ^a   Fanwick, Phillip E ^b   Green, Mark A ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Gallium 68; Myocardial imaging; Positron emission tomography, PET; Radiopharmaceuticals

Indexed keywords

BIS(3 METHOXYSALICYLALDIMINE) GA 67; BIS(4 METHOXYSALICYLALDIMINE) GA 67; BIS(4,6 DIMETHOXYSALICYLALDIMINE) GA 67; BIS(6 METHOXYSALICYLALDIMINE) GA 67; BIS(SALICYLALDIMINE) GA 67; CHELATE; GALLIUM 67; GALLIUM 68; LIGAND; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN 1; N,N' BIS(3 AMINOPROPYL) N,N' DIMETHYLETHYLENEDIAMINE GA 67; RADIOPHARMACEUTICAL AGENT; RUBIDIUM CHLORIDE RB 86; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSPORT; HALF LIFE TIME; HEART; HEART MUSCLE PERFUSION; KIDNEY; LIPOPHILICITY; LIVER; LUNG; MALE; MUSCLE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RAT; SPLEEN; TISSUE DISTRIBUTION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CHELATING AGENTS; CHLORIDES; ETHYLENEDIAMINES; GALLIUM RADIOISOTOPES; HEART; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RADIOPHARMACEUTICALS; RATS; RUBIDIUM; RUBIDIUM RADIOISOTOPES; TISSUE DISTRIBUTION;

EID: 58749114785     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.10.010     Document Type: Article

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