Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis

Environmental and Molecular Mutagenesis

Volumn 50, Issue 1, 2009, Pages 46-59

  Kawata, Koji ^a   Shimazaki, Ryuhei ^a   Okabe, Satoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Arsenic; Cadmium; DNA microarray; Nickel; PTTG1; Reactive oxygen species

Indexed keywords

ARSENIC; ASCORBIC ACID; CADMIUM; CARCINOGEN; N DIMETHYLNITROSOAMINE; NICKEL; PHORBOL 13 ACETATE 12 MYRISTATE; SECURIN; TETRACHLOROETHYLENE; UNCLASSIFIED DRUG; PRIMER DNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; DNA REPAIR; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; CELL LINE; CELL TRANSFORMATION; COMPARATIVE STUDY; GENE EXPRESSION PROFILING; METABOLISM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ARSENIC; BASE SEQUENCE; CADMIUM; CARCINOGENS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; DNA PRIMERS; GENE EXPRESSION PROFILING; HUMANS; NICKEL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 58749112908     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20438     Document Type: Article

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