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Volumn 18, Issue 1, 2009, Pages 78-86

The health impact fund: Boosting pharmaceutical innovation without obstructing free access

(1)  Pogge, Thomas a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DRUG COST; DRUG INDUSTRY; ECONOMICS; ETHICS; FINANCIAL MANAGEMENT; HEALTH CARE DELIVERY; HUMAN; ORGANIZATION AND MANAGEMENT; PATENT; POVERTY;

EID: 58749098635     PISSN: 09631801     EISSN: 14692147     Source Type: Journal    
DOI: 10.1017/S0963180108090129     Document Type: Article
Times cited : (14)

References (14)
  • 1
    • 33947395240 scopus 로고    scopus 로고
    • Montréal Statement on the Human Right to Essential Medicines
    • Pogge T. Montréal Statement on the Human Right to Essential Medicines. Cambridge Quarterly of Healthcare Ethics 2007;16:97-108.
    • (2007) Cambridge Quarterly of Healthcare Ethics , vol.16 , pp. 97-108
    • Pogge, T.1
  • 3
    • 68349132844 scopus 로고    scopus 로고
    • Patent life is counted from the time the patent application is filed. Effective patent life is the time from receiving market clearance to the time the patent expires. My calculation in the text assumes constant nominal profit each year. In reality, annual profit may rise (due to increasing market penetration or population growth) or fall (through reduced incidence of the disease or through competition from me-too drugs developed by competing firms). For most drugs, sales decline steeply after they have been on the market for 6 years or so, and this strengthens the reasons for limiting patent life.
    • Patent life is counted from the time the patent application is filed. Effective patent life is the time from receiving market clearance to the time the patent expires. My calculation in the text assumes constant nominal profit each year. In reality, annual profit may rise (due to increasing market penetration or population growth) or fall (through reduced incidence of the disease or through competition from "me-too drugs" developed by competing firms). For most drugs, sales decline steeply after they have been on the market for 6 years or so, and this strengthens the reasons for limiting patent life.
  • 4
    • 68349153886 scopus 로고    scopus 로고
    • The promise was broken as the high-income countries continue to sabotage the export opportunities of poor countries through protectionist tariffs and anti-dumping duties as well as through huge subsidies and export credits to their domestic producers
    • The promise was broken as the high-income countries continue to sabotage the export opportunities of poor countries through protectionist tariffs and anti-dumping duties as well as through huge subsidies and export credits to their domestic producers.
  • 5
    • 68349145775 scopus 로고    scopus 로고
    • Announced in 2003, this joint WHO/ UNAIDS program was meant to provide, by 2005, anti-retroviral treatment to 3 million (out of what were then estimated to be 40.3 million) AIDS patients in the less developed countries. In fact, it extended such treatment to about 900,000.
    • Announced in 2003, this joint WHO/ UNAIDS program was meant to provide, by 2005, anti-retroviral treatment to 3 million (out of what were then estimated to be 40.3 million) AIDS patients in the less developed countries. In fact, it extended such treatment to about 900,000.
  • 6
    • 68349160087 scopus 로고    scopus 로고
    • A prize is a specific reward offered for the development of a new medicine that meets certain specifications. It can be in the form of a cash payment or in some other form, for instance, the extension of a patent on another medicine that is in high demand by affluent patients. An AMC is a promise to subsidize the sale of a certain large number of doses of a new medicine that meets certain specifications. An advance purchase commitment is a promise to buy, at a preset high price, a certain large number of doses of a new medicine that meets certain specifications
    • A prize is a specific reward offered for the development of a new medicine that meets certain specifications. It can be in the form of a cash payment or in some other form, for instance, the extension of a patent on another medicine that is in high demand by affluent patients. An AMC is a promise to subsidize the sale of a certain large number of doses of a new medicine that meets certain specifications. An advance purchase commitment is a promise to buy, at a preset high price, a certain large number of doses of a new medicine that meets certain specifications.
  • 7
    • 68349134627 scopus 로고    scopus 로고
    • Personal communication from Aidan Hollis, based on his rough calculation. See also Hollis A. An efficient reward system for pharmaceutical innovation; 2005:8 at www. econ.ucalgary.ca/fac-files/ah/dragprizes.pdf (retrieved 2008 Jul 16), where he quantifies the deadweight loss in the region of $5 bn - 20 bn annually for the US. Globally the deadweight loss is certain to be many times this figure, because in many markets drug insurance is unavailable and so consumers are more price-sensitive.
    • Personal communication from Aidan Hollis, based on his rough calculation. See also Hollis A. An efficient reward system for pharmaceutical innovation; 2005:8 at www. econ.ucalgary.ca/fac-files/ah/dragprizes.pdf (retrieved 2008 Jul 16), where he quantifies the deadweight loss in the region "of $5 bn - 20 bn annually for the US. Globally the deadweight loss is certain to be many times this figure, because in many markets drug insurance is unavailable and so consumers are more price-sensitive."
  • 8
    • 33646231981 scopus 로고    scopus 로고
    • See the special issue on disease mongering, Moynihan R, Henry D, eds. PLoS Medicine 2006;3:425-65.
    • See the special issue on disease mongering, Moynihan R, Henry D, eds. PLoS Medicine 2006;3:425-65.
  • 9
    • 68349156921 scopus 로고    scopus 로고
    • This corresponds roughly to the profitable period of a patent: Under TRIPS, members of the World Trade Organization must offer patents lasting at least 20 years from the patent filing date, which is typically many years before the medicine receives market clearance after clinical trials
    • This corresponds roughly to the profitable period of a patent: Under TRIPS, members of the World Trade Organization must offer patents lasting at least 20 years from the patent filing date, which is typically many years before the medicine receives market clearance after clinical trials.
  • 10
    • 68349129708 scopus 로고    scopus 로고
    • See note 2, Pogge 2008:ch. 9.
    • See note 2, Pogge 2008:ch. 9.
  • 11
    • 68349142715 scopus 로고    scopus 로고
    • For further details, see also Pogge T. Medicines for the World. Sur: Revista Internacional de direitos humanos; 2008:8. Additional work by team members is available at www.yale.edu/macmillan/igh/e-library.html. A special issue of the journal Public Health Ethics; 2008(1):2 features critical discussions of the proposal by Gorik Ooms and Rachel Hammonds, Thomas Faunce and Hitoshi Nasu, Devi Sridhar, Michael Selgelid, Aidan Hollis, and Michael Ravvin.
    • For further details, see also Pogge T. Medicines for the World. Sur: Revista Internacional de direitos humanos; 2008:8. Additional work by team members is available at www.yale.edu/macmillan/igh/e-library.html. A special issue of the journal Public Health Ethics; 2008(1):2 features critical discussions of the proposal by Gorik Ooms and Rachel Hammonds, Thomas Faunce and Hitoshi Nasu, Devi Sridhar, Michael Selgelid, Aidan Hollis, and Michael Ravvin.
  • 12
    • 67650251861 scopus 로고    scopus 로고
    • The Health Impact Fund: A useful supplement to the patent system?
    • Hollis A. The Health Impact Fund: A useful supplement to the patent system? Public Health Ethics 2008;1(2):123-33.
    • (2008) Public Health Ethics , vol.1 , Issue.2 , pp. 123-133
    • Hollis, A.1
  • 13
    • 68349142716 scopus 로고    scopus 로고
    • The only existing AMC thus far, funded by Italy, the United Kingdom, Canada, Russia, Norway, and the Gates Foundation, is for vaccines against pneumococcal disease, a major cause of pneumonia and meningitis among the poor
    • The only existing AMC thus far - funded by Italy, the United Kingdom, Canada, Russia, Norway, and the Gates Foundation - is for vaccines against pneumococcal disease, a major cause of pneumonia and meningitis among the poor.
  • 14
    • 73349095099 scopus 로고    scopus 로고
    • Incentive Mechanisms for Innovation. IAPR
    • For an excellent discussion, see, Available from, retrieved 2008 Jul 16
    • For an excellent discussion, see Hollis A. Incentive Mechanisms for Innovation. IAPR Technical Paper; 2007:15-6. Available from www.iapr.ca/iapr/ files/iapr/iapr-tp-07005-0.pdf (retrieved 2008 Jul 16).
    • (2007) Technical Paper , pp. 15-16
    • Hollis, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.