A polyomavirus may cause merkel cell carcinoma: Implications for immunosuppressed states and viral reactivation

Journal of Drugs in Dermatology

Volumn 7, Issue 11, 2008, Pages 1104-1105

  Bergstrom, Kendra Gail ^a,b  

^a Manhattan Dermatology   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EFALIZUMAB; MONOCLONAL ANTIBODY; RITUXIMAB;

ARTICLE; BK VIRUS; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNE DEFICIENCY; JC VIRUS; MERKEL CELL TUMOR; POLYOMA VIRUS; SKIN TUMOR; VIROLOGY; VIRUS INFECTION;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BK VIRUS; CARCINOMA, MERKEL CELL; GENE EXPRESSION PROFILING; HUMANS; IMMUNOCOMPROMISED HOST; JC VIRUS; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; SKIN NEOPLASMS;

EID: 58749091096     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (7)

1. Lemos B, Nghiem P. Merkel cell carcinoma: more deaths but still no pathway to blame. J Invest Dermatol. 2007 Sep;127(9):2100-3.
2. Heath M, Jaimes N, et al. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol. 2008 Mar;58(3):375-381.
3. Feng H, Shuda M, Chang Y, Moore PS. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008 Feb 22;319(5866):1096-1100. Epub 2008 Jan 17.
4. Garneski KM, Warcola AH, Feng Q, et al. Merkel Cell Polyomavirus Is More Frequently Present in North American than Australian Merkel Cell Carcinoma Tumors. J Invest Dermatol. 2008 Jul 24.
5. Becker JC, Houben R, et al. MC Polyomavirus is frequently present in Merkel cell carcinoma of european patients. J Invest Dermatol. 2008 Jul 17. [Epub ahead of print]
6. http://www.fda.gov/medwatch/safety/2006/safety06.htm#rituxan, accessed October 17, 2008.
7. http://www.fda.gov/bbs/topics/NEWS/2008/NEW01905.html, accessed October 17, 2008.