5-S-GAD, a novel radical scavenging compound, prevents lens opacity development

Free Radical Biology and Medicine

Volumn 46, Issue 4, 2009, Pages 511-519

  Akiyama, Nobuko ^a   Umeda, Izumi O ^b   Sogo, Shunji ^c   Nishigori, Hideo ^d   Tsujimoto, Masafumi ^a   Natori, Shunji ^a  

^a RIKEN   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

^c MEI Inc   (Japan)

^d IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

5 S GAD; Cataract; Cataract therapy; Crystallin; Free radical scavengers; Lens; Oxidative stress

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALPHA CRYSTALLIN; CARNOSINE; CATECHOL DERIVATIVE; DIAMIDE; FREE RADICAL; GALACTOSE; GLUCOCORTICOID; LIPID; N BETA ALANYL5 S GLUTATHIONYL 3,4 DIHYDROXYPHENYLALANINE; PROTEIN; SCAVENGER; SUPEROXIDE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBONYLATION; CATARACT; CHEMICAL ANALYSIS; CHICK EMBRYO; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; DRUG INSTILLATION; EMBRYO; FEEDING; INSECT; LIPID PEROXIDATION; MALE; NONHUMAN; OPTICAL INSTRUMENTATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALPHA-CRYSTALLINS; ANIMALS; BIPHENYL COMPOUNDS; CARNOSINE; CATARACT; CELLS, CULTURED; CHICK EMBRYO; CYCLIC N-OXIDES; DIAMIDE; DIHYDROXYPHENYLALANINE; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; GALACTOSE; GLUCOCORTICOIDS; GLUTATHIONE; INSECTS; LENS, CRYSTALLINE; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PICRATES; PROTEIN CARBONYLATION; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; SUPEROXIDES;

HEXAPODA; RATTUS;

EID: 58649110825     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.11.010     Document Type: Article

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