Effect of etonogestrel contraceptive implant (Implanon®) on portal blood flow and liver functions

Contraception

Volumn 79, Issue 3, 2009, Pages 236-239

  Nasr, Ahmed ^a   Nafeh, Hanan M ^b  

^a ASSIUT UNIVERSITY   (Egypt)

^b Assiut University Faculty of Medicine   (Egypt)

Author keywords

Etonogestrel; Implanon; Liver functions; Portal vein

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; ETONOGESTREL; GAMMA GLUTAMYLTRANSFERASE; SERUM ALBUMIN;

ALBUMIN BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CLINICAL ARTICLE; COLOR ULTRASOUND FLOWMETRY; CONTRACEPTION; ENZYME BLOOD LEVEL; FEMALE; FEMALE CONTRACEPTIVE DEVICE; HUMAN; IMPLANT; LIVER FUNCTION; LIVER FUNCTION TEST; PORTAL VEIN BLOOD FLOW; PROTHROMBIN TIME;

ADULT; CONTRACEPTIVE AGENTS, FEMALE; DESOGESTREL; FEMALE; HUMANS; LIVER; LIVER CIRCULATION; LIVER FUNCTION TESTS; YOUNG ADULT;

EID: 58649107375     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2008.09.010     Document Type: Article

References (24)

1. Le J., and Tsourounis C. Implanon: a critical review. Ann Pharmacother 35 (2001) 329-336
2. Croxatto H.B. Clinical profile of Implanon: a single-rod etonogestrel contraceptive implant. Eur J Contracept Reprod Health Care 5 Suppl 2 (2000) 21-28
3. Ogbonmwan S., Briggs P., and Amu O. The oestrogen 'sparing' effect of Implanon: a case report and review. Eur J Contracept Reprod Health Care 11 (2006) 109-111
4. Bahamondes L., Monteiro-Dantas C., Espejo-Arce X., et al. A prospective study of the forearm bone density of users of etonorgestrel- and levonorgestrel-releasing contraceptive implants. Hum Reprod 21 (2006) 466-470
5. Funk S., Miller M.M., Mishell Jr. D.R., et al. The Implanon US Study Group. Safety and efficacy of Implanon, a single-rod implantable contraceptive containing etonogestrel. Contraception 71 (2005) 319-326
6. Flores J.B., Balderas M.L., Bonilla M.C., and Vázquez-Estrada L. Clinical experience and acceptability of the etonogestrel subdermal contraceptive implant. Int J Gynaecol Obstet 90 (2005) 228-233
7. Varma R., and Mascarenhas L. Endometrial effects of etonogestrel (Implanon) contraceptive implant. Curr Opin Obstet Gynecol 13 (2001) 335-341
8. Korhonen T., Tolonen A., Uusitalo J., Lundgren S., Jalonen J., and Laine K. The role of CYP2C and CYP3A in the disposition of 3-keto-desogestrel after administration of desogestrel. Br J Clin Pharmacol 60 (2005) 69-75
9. Bennink H.J. The pharmacokinetics and pharmacodynamics of Implanon, a single-rod etonogestrel contraceptive implant. Eur J Contracept Reprod Health Care 5 Suppl 2 (2000) 12-20
10. Dorflinger L.J. Metabolic effects of implantable steroid contraceptives for women. Contraception 65 (2002) 47-62
11. Egberg N., van Beek A., Gunnervik C., et al. Effects on the hemostatic system and liver function in relation to Implanon and Norplant. A prospective randomized clinical trial. Contraception 58 (1998) 93-98
12. Lindqvist P.G., Rosing J., Malmquist A., and Hillarp A. Etonogestrel implant use is not related to hypercoagulable changes in anticoagulant system. J Thromb Haemost 1 (2003) 601-602
13. Biswas A., Viegas O.A., Coeling Bennink H.J., Korver T., and Ratnam S.S. Implanon contraceptive implants: effects on carbohydrate metabolism. Contraception 63 (2001) 137-141
14. Biswas A., Viegas O.A., Bennink H.J., Korver T., and Ratnam S.S. Effect of Implanon use on selected parameters of thyroid and adrenal function. Contraception 62 (2000) 247-251
15. Biswas A., Biswas S., and Viegas O.A. Effect of etonogestrel subdermal contraceptive implant (Implanon) on liver function tests - a randomized comparative study with Norplant implants. Contraception 70 (2004) 379-382
16. Partiquin H., Lafortune M., Burns P.N., and Dauzat M. Duplex Doppler examination in portal hypertension: technique and anatomy. Am J Roentgenol 149 (1987) 71-76
17. de Vries P.J., Van Hattum J., Hoekstra J.B.L., et al. Duplex Doppler measurements of portal venous flow in normal subjects. Inter and intra-observer variability. J Hepatol 13 (1991) 358-363
18. Haag K., and Lanzer P. Abdominal and pelvic vascular ultrasonography. In: Lanzer P., and Rosch J. (Eds). Vascular diagnostics (1994), Springer-Verlag, Berlin 139-162
19. Moriyasu F., Ban N., Nishida O., et al. Clinical application on an ultrasonic duplex system in the quantitative measurement of portal blood flow. J Clin Ultrasound 14 (1986) 579-588
20. Quick A.J. Haemorrhagic diseases and thrombosis (1966), Lee and Febiger, Philadelphia
21. Piscaglia F., Gaiani S., Donati G., Masi L., and Bolondi L. Doppler evaluation of the effects of pharmacological treatment of portal hypertension. Ultrasound Med Biol 25 (1999) 923-932
22. Cioni G., D'Alimonte P., Zerbinati F., et al. Duplex-Doppler ultrasonography in the evaluation of cirrhotic patients with portal hypertension and in the analysis of their response to drugs. J Gastroenterol Hepatol 7 (1992) 388-392
23. Lonardo A., Grisendi A., Frazzoni M., Pulvirenti M., and Della Casa G. Portal vein thrombosis (PVT) associated with oral contraceptive steroids (OCS). J Gastroenterol Hepatol 9 (1994) 314
24. Sherlock S., and Dooley J. Assessment of liver function. In: Sherlock S., and Dooley J. (Eds). Diseases of the liver and biliary system. XI (2002), Blackwell Scientific Publications, Oxford 19-35