A novel approach to align adult neural stem cells on micropatterned conduits for peripheral nerve regeneration: A feasibility study

Artificial Organs

Volumn 33, Issue 1, 2009, Pages 26-35

  Hsu, Shan Hui ^a,b,c   Su, Chien Hsiang ^b   Chiu, Ing Ming ^c,d  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b Department of Chemical Engineering ^*  (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Cell alignment; Micropattern; Neural stem cells; Poly(d,l lactide)

Indexed keywords

CELL ENGINEERING; CYTOLOGY; GENE EXPRESSION; MOLECULAR BIOLOGY; STEM CELLS; TISSUE REGENERATION;

CELL ALIGNMENT; CELL-BE; CELL/B.E; CELL/BE; L-LACTIDE; MICRO PATTERN; MICROPATTERNED; NEURAL STEM CELL; PERIPHERAL NERVE REGENERATION; POLY(D,L-LACTIDE);

NEURONS;

GREEN FLUORESCENT PROTEIN; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; POLYLACTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FEASIBILITY STUDY; GENE EXPRESSION; IN VITRO STUDY; MOUSE; NERVE REGENERATION; NERVOUS TISSUE; NEURAL STEM CELL; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SCHWANN CELL; SCIATIC NERVE; TISSUE ENGINEERING; UPREGULATION;

RATTUS;

EID: 58649088036     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2008.00671.x     Document Type: Article

References (50)

1. Heath CA, Rutkowski GE. The development of bioartificial nerve grafts for peripheral-nerve regeneration. Trends Biotechnol 1998 16 : 163 8.
2. Zhao Q, Lundborg G, Danielsen N, Bjursten LM, Dahlin LB. Nerve regeneration in a "pseudo-nerve" graft created in a silicone tube. Brain Res 1997 769 : 125 34.
3. Suzuki Y, Tanihara M, Ohnishi K, Suzuki K, Endo K, Nishimura Y. Cat peripheral nerve regeneration across 50 mm gap repaired with a novel nerve guide composed of freeze-dried alginate gel. Neurosci Lett 1999 259 : 75 8.
4. Evans GRD, Brandt K, Widmer MS, et al. In vivo evaluation of poly(L-lactic acid) porous conduits for peripheral nerve regeneration. Biomaterials 1999 20 : 1109 15.
5. Wang S, Wan ACU, Xu X, et al. A new nerve guide conduit material composed of a biodegradable poly(phosphoester). Biomaterials 2001 22 : 1157 69.
6. Itoh S, Takakuda K, Kawabata S, et al. Evaluation of cross-linking procedures of collagen tubes used in peripheral nerve repair. Biomaterials 2002 23 : 4475 81.
7. Keilhoff G, Stang F, Wolf G, Fansa F. Bio-compatibility of type I/III collagen matrix for peripheral nerve reconstruction. Biomaterials 2003 203 : 2779 87.
8. Ahmed AM, Venkateshwarlu U, Jayakumar R. Multilayered peptide incorporated collagen tubules for peripheral nerve repair. Biomaterials 2004 25 : 2585 94.
9. Gamez E, Goto Y, Nagata K, Iwaki T, Sasaki T, Matsuda T. Photofabricated gelatin-based nerve conduits: nerve tissue regeneration potentials. Cell Transplant 2004 13 : 549 64.
10. Ide C. Peripheral nerve regeneration. Neurosci Res 1996 25 : 101 21.
11. Pantazis NJ, Zaheer A, Dai D, Zaheer S, Green SH, Lim R. Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells. Brain Res 2000 865 : 59 76.
12. Evans GRD, Brandt K, Katz S, et al. Bioactive poly(l-lactic acid) conduits seeded with Schwann cells for peripheral nerve regeneration. Biomaterials 2002 23 : 841 8.
13. Mosahebi A, Fuller P, Wiberg M, Terenghi G. Effect of allogeneic Schwann cell transplantation on peripheral nerve regeneration. Exp Neurol 2002 173 : 213 23.
14. Schlosshauer B, Muller E, Schroder B, Planck H, Muller HW. Rat Schwann cells in bioresorbable nerve guides to promote and accelerate axonal regeneration. Brain Res 2003 963 : 321 6.
15. Chen PR, Chen MH, Sun JS, Chen MH, Tsai CC, Lin FH. Biocompatibility of NGF-grafted GTG membranes for peripheral nerve repair using cultured Schwann cells. Biomaterials 2004 25 : 5667 73.
16. Komiyama T, Nakao Y, Toyama Y, Vacanti CA, Vacanti MP, Ignotz RA. Novel technique for peripheral nerve reconstruction in the absence of an artificial conduit. J Neurosci Methods 2004 134 : 133 40.
17. Miller C, Shanks H, Witt A, Rutkowski G, Mallapragada S. Oriented Schwann cell growth on micropatterned biodegradable polymer substrates. Biomaterials 2001 22 : 1263 9.
18. Manwaring ME, Walsh JF, Tresco PA. Contact guidance induced organization of extracellular matrix. Biomaterials 2004 25 : 3631 8.
19. Recknor JB, Recknor JC, Sakaguchi DS, Mallapragada SK. Oriented astroglial cell growth on micropatterned polystyrene substrates. Biomaterials 2004 25 : 2753 67.
20. Matsumoto K, Ohnishi K, Kiyotani T, et al. Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid (PGA)-collagen tube filled with laminin-coated collagen fibers: a histological and electrophysiological evaluation of regenerated nerves. Brain Res 2000 868 : 315 28.
21. Bender MD, Bennett JM, Waddell RL, Doctor JS, Marra KG. Multi-channeled biodegradable polymer/CultiSpher composite nerve guides. Biomaterials 2004 25 : 1269 78.
22. Thompson DM, Buettner HM. Schwann cell response to micropatterned laminin surfaces. Tissue Eng 2001 7 : 247 65.
23. Thompson DM, Buettner HM. Oriented Schwann cell monolayers for directed neurite outgrowth. Ann Biomed Eng 2004 32 : 1120 30.
24. Schmalenberg KE, Uhrich KE. Micropatterned polymer substrates control alignment of proliferating Schwann cells to direct neuronal regeneration. Biomaterials 2005 26 : 1423 30.
25. Rutkowski GE, Miller CA, Jeftinija S, Mallapragada SK. Synergistic effects of micropatterned biodegradable conduits and Schwann cells on sciatic nerve regeneration. J Neural Eng 2004 1 : 151 7.
26. Teng YD, Lavik EB, Qu X, et al. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci USA 2002 99 : 3024 9.
27. Murakami T, Fujimoto Y, Yasunaga Y, et al. Transplanted neuronal progenitor cells in a peripheral nerve gap promote nerve repair. Brain Res 2003 974 : 17 24.
28. Heine W, Conant K, Griffin JW, Hoke A. Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves. Exp Neurol 2004 189 : 231 40.
29. Hsu SH, Chen CY, Lu PS, Lai CS, Chen CJ. Oriented Schwann cell growth on microgrooved surfaces. Biotechnol Bioeng 2005 92 : 579 88.
30. Chiu IM, Touhalisky K, Liu Y, Yates A, Frostholm A. Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter. Oncogene 2000 19 : 6229 39.
31. US Patent 6,984,518.
32. US Patent 7,045,678.
33. Laywell ED, Kukekov VG, Suslov O, Zheng T, Steindler DA. Production and analysis of neurospheres from acutely dissociated and postmortem CNS specimens. Methods Mol Biol 2002 198 : 15 27.
34. Chiu IM, Touhalisky K, Baran C. Multiple controlling mechanisms of FGF1 gene expression through multiple tissue-specific promoters. Prog Nucleic Acid Res Mol Biol 2001 70 : 155 74.
35. Corish P, Tyler-Smith C. Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 1999 12 : 1035 40.
36. Hsu SH, Tsai IJ, Lin DJ, Chen DC. The effect of dynamic culture conditions on endothelial cell seeding and retention on small-diameter polyurethane vascular grafts. Med Eng Phys 2005 27 : 267 72.
37. Hare GM, Evans PJ, Mackinnon SE, et al. Walking track analysis: a long-term assessment of peripheral nerve recovery. Plast Reconstr Surg 1992 89 : 251 8.
38. Nie X, Zhang YJ, Tian WD, et al. Improvement of peripheral nerve regeneration by a tissue-engineered nerve filled with ectomesenchymal stem cells. Int J Oral Maxillofac Surg 2007 36 : 32 8.
39. Keilhoff G, Goihl A, Stang F, Wolf G, Fansa H. Peripheral nerve tissue engineering: autologous Schwann cells vs. transdifferentiated mesenchymal stem cells. Tissue Eng 2006 12 : 1451 65.
40. Hou SY, Zhang HY, Quan DP, Liu XL, Zhu JK. Tissue-engineered peripheral nerve grafting by differentiated bone marrow stromal cells. Neuroscience 2006 140 : 101 10.
41. Mimura T, Dezawa M, Kanno H, Sawada H, Yamamoto I. Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats. J Neurosurg 2004 101 : 806 12.
42. Chen X, Wang XD, Chen G, Lin WW, Yao J, Gu XS. Study of in vivo differentiation of rat bone marrow stromal cells into Schwann cell-like cells. Microsurgery 2006 26 : 111 5.
43. Tohill M, Mantovani C, Wiberg M, Terenghi G. Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration. Neurosci Lett 2004 362 : 200 3.
44. Recknor JB, Sakaguchi DS, Mallapragada SK. Directed growth and selective differentiation of neural progenitor cells on micropatterned polymer substrates. Biomaterials 2006 27 : 4098 108.
45. Hsu SH, Lu PS, Ni HC, Su CH. Fabrication and evaluation of microgrooved polymers as peripheral nerve conduits. Biomed Microdevices 2007 9 : 665 74.
46. Midha R, Munro CA, Dalton PD, Tator CH, Shoichet MS. Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube. J Neurosurg 2003 99 : 555 65.
47. Wang S, Cai Q, Hou J, et al. Acceleration effect of basic fibroblast growth factor on the regeneration of peripheral nerve through a 15-mm gap. J Biomed Mater Res A 2003 66 : 522 31.
48. Timmer M, Robben S, Muller-Ostermeyer F, Nikkhah G, Grothe C. Axonal regeneration across long gaps in silicone chambers filled with Schwann cells overexpressing high molecular weight FGF-2. Cell Transplant 2003 12 : 265 77.
49. Li Q, Ping P, Jiang H, Liu K. Nerve conduit filled with GDNF gene-modified Schwann cells enhances regeneration of the peripheral nerve. Microsurgery 2006 26 : 116 21.
50. Merkle FT, Mirzadeh Z, Alvarez-Buylla A. Mosaic organization of neural stem cells in the adult brain. Science 2007 317 : 381 4.