A Neisseria meningitidis NMB1966 mutant is impaired for invasion of respiratory epithelial cells, survival in human blood and for virulence in vivo

Medical Microbiology and Immunology

Volumn 198, Issue 1, 2009, Pages 57-67

  Li, Ming Shi ^a   Chow, Noel Y S ^b   Sinha, Sunita ^a   Halliwell, Denise ^c   Finney, Michelle ^c   Gorringe, Andrew R ^c   Watson, Mark W ^d   Kroll, J Simon ^a   Langford, Paul R ^a   Webb, Steven A R ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d ROYAL PERTH HOSPITAL   (Australia)

Author keywords

Glutamate transport; Neisseria meningitidis; Outer membrane; Pathogenesis; Transcriptome

Indexed keywords

ABC TRANSPORTER; ADHESIN; BACTERIAL PROTEIN; GLUTAMATE TRANSPORTER; OUTER MEMBRANE PROTEIN; PEPTIDOGLYCAN; PROTEIN NMB1966; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BLOOD; CELL ADHESION; CELL INVASION; CELL SURVIVAL; CONTROLLED STUDY; EPITHELIUM CELL; GENE CONTROL; IN VIVO STUDY; MENINGOCOCCOSIS; MOUSE; MUTANT; NEISSERIA MENINGITIDIS; NONHUMAN; OPERON; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; WILD TYPE;

ADHESINS, BACTERIAL; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL ADHESION; BLOOD; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE KNOCKOUT TECHNIQUES; HUMANS; MEMBRANE TRANSPORT PROTEINS; MICE; MICROBIAL VIABILITY; NEISSERIA MENINGITIDIS; VIRULENCE; VIRULENCE FACTORS;

EID: 58549112573     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-008-0105-2     Document Type: Article

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