Formation of diazoate intermediate upon nitrous acid and nitric oxide treatment of 2′-deoxyadenosine

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 3, 2009, Pages 788-791

  Suzuki, Toshinori ^a   Iwakura, Kiyoshi ^a   Takashima, Yasuhide ^a   Kasajima, Naoki ^a   Inukai, Michiyo ^a  

^a SHUJITSU UNIVERSITY   (Japan)

Author keywords

2 Deoxyadenosine; 2 Deoxyinosine; Diazoate; Nitric oxide; Nitrous acid

Indexed keywords

AMYL NITRITE; AZO COMPOUND; DEOXYADENOSINE; DNA; NITRIC OXIDE; NITROUS OXIDE; TETRAHYDROFURAN;

ARTICLE; DEAMINATION; DECOMPOSITION; HALF LIFE TIME; MOLECULAR STABILITY; PH; REACTION ANALYSIS;

AMINES; CHEMISTRY; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYADENOSINES; DRUG DESIGN; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; NITRIC OXIDE; NITROUS ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE; TIME FACTORS;

EID: 58549106952     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.12.012     Document Type: Article

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