Anticonvulsant properties of saponins from Ficus platyphylla stem bark

Brain Research Bulletin

Volumn 78, Issue 6, 2009, Pages 276-282

  Chindo, Ben A ^a,c   Anuka, Joseph A ^b   McNeil, Lilly ^c   Yaro, Abdullahi H ^b   Adamu, Simon S ^d   Amos, Samson ^a,e   Connelly, William K ^c   Lees, George ^c   Gamaniel, Karniyus S ^a  

^a NATIONAL INSTITUTE FOR PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (Nigeria)

^b AHMADU BELLO UNIVERSITY   (Nigeria)

^c UNIVERSITY OF OTAGO   (New Zealand)

^d UNIVERSITY OF MAIDUGURI   (Nigeria)

^e UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Epilepsy; Ficus platyphylla; Saponins; Voltage gated sodium channels

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOPYRIDINE; CLONAZEPAM; FICUS PLATYPHYLLA EXTRACT; PENTETRAZOLE; PHENOBARBITAL; PLANT EXTRACT; SAPONIN; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BARK; BRAIN NERVE CELL; CELL CULTURE; CHLORIDE CURRENT; CONTROLLED STUDY; DROWSINESS; DRUG ISOLATION; ELECTRIC SHOCK; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; FICUS; FICUS PLATYPHYLLA; GRAND MAL EPILEPSY; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MEMBRANE DEPOLARIZATION; MOTOR DYSFUNCTION; MOUSE; MYOCLONUS SEIZURE; NONHUMAN; PLANT STEM; PRIORITY JOURNAL; RAT; SEDATION; TENDON REFLEX; TONIC SEIZURE;

4-AMINOPYRIDINE; ANIMALS; ANTICONVULSANTS; BRAIN; CELLS, CULTURED; ELECTROSHOCK; FEMALE; FICUS; MALE; MEMBRANE POTENTIALS; MICE; NEURONS; PENTYLENETETRAZOLE; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SAPONINS; SEIZURES; STRYCHNINE;

EID: 58549102541     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2008.12.005     Document Type: Article

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