Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system

International Journal of Laboratory Hematology

Volumn 31, Issue 1, 2009, Pages 48-60

  Briggs, C ^a   Longair, I ^a   Slavik, M ^b   Thwaite, K ^b   Mills, R ^a   Thavaraja, V ^a   Foster, A ^c   Romanin, D ^c   MacHin, S J ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c SYSMEX CORPORATION   (Japan)

Author keywords

Automated image analysis; Leucocyte differential; Microscopy

Indexed keywords

ACCURACY; ARTICLE; AUTOMATION; CONTROLLED STUDY; ERYTHROCYTE STRUCTURE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LEUKOCYTE DIFFERENTIAL COUNT; LEUKOCYTE STRUCTURE; LYMPHOCYTE; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; THROMBOCYTE COUNT; THROMBOCYTE STRUCTURE;

AUTOMATION; BLOOD SPECIMEN COLLECTION; HEMATOLOGIC TESTS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; TECHNOLOGY, MEDICAL;

EID: 58449128069     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2007.01002.x     Document Type: Article

References (10)

1. Barnes P.W., McFadden S.L., Machin S.J. Simson E. (2005) The international consensus group for hematology review: suggested criteria for action following automated CBC and WBC differential analysis. Laboratory Hematology 11, 83 90.
2. Bentley S.A. (1990) Automated differential white cell counts: a critical appraisal. Bailliere's Clinical Haematology 3, 851 869.
3. Clinical and Laboratory Standards Institute. (2007) Reference Leukocyte (WBC) Differential Count (Proportional) and Evaluation of Instrument Methods; Approved Standard, 2nd edn. Vol 27, No 4.
4. Koepke J.A., Dotson M.A. Shifmann M.A. (1985) A critical evaluation of the manual/visual differential leukocyte counting method. Blood Cells 11, 173 186.
5. Kratz A., Bengtsson H., Casey J.E., Keefe J.M., Beatrice G.H., Grzbek D.Y., Lewandrowski K.B. Van Cott E.M. (2006) Performance evaluation of the CellaVision DM96 system. American Journal of Pathology 124, 770 781.
6. Lewis S.M. Rowan M. (1991) Assessment of the need for blood film examination with blood counts by aperture-impedance systems. In : Standard Haematology Practice (ed B. Roberts pp. 34 42. Blackwell Scientific Publications, Osney Mead, Oxford, UK.
7. Prewitt J.M. Mendlesohn M.L. (1966) The analysis of cell images. Annals of the New York Academy of Sciences 128, 1035 1053.
8. Rumke C.L. (1985a) Statistical reflections on finding atypical cells. Blood Cells 11, 141 144.
9. Rumke C.L. (1985b) Imprecision of ratio-derived differential leucocyte counts. Blood Cells 11, 311 314, 315.
10. Tatsumi N. Pierre R.V. (2002) Automated image processing. Past, present and future of blood cell morphology identification. Clinics in Laboratory Medicine 22, 299 315.