The potential role of the nodose ganglion adenosine A1 receptor in regulation of breathing in anaesthetized rats

Journal of Physiology and Pharmacology

Volumn 59, Issue 4, 2008, Pages 759-770

  Kaczynska, Katarzyna ^a   Szereda Przestaszewska, M ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

A1 receptors; CPA; Lung afferents; Nodosal vagal afferents; Pattern of breathing

Indexed keywords

ADENOSINE A1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING RATE; CONTROLLED STUDY; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; NODOSE GANGLION; NONHUMAN; PROTEIN EXPRESSION; RAT; RESPIRATION CONTROL; SENSORY NERVE; TIDAL VOLUME;

ADENOSINE; ANIMALS; BLOOD PRESSURE; HEART RATE; MALE; NODOSE GANGLION; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; RESPIRATORY MECHANICS; TIDAL VOLUME; VAGOTOMY; XANTHINES;

EID: 58449115793     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. 2 receptors in the cat vascular bed. Am J Physiol Regulatory Integrative Comp Physiol 2002; 282: R1696-R1709.
2. Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001; 24: 31-55.
3. Wang JL, Wu ZH, Wang NQ. Adenosine A1 receptors are involved in the modulation of the rhythmical respiration in neonatal rat brainstem slice in vitro. Acta Physiol Sinica 2005; 57: 91-96.
4. Hedner T, Hedner J, Jonason J. Regulation of breathing in the rat: indications for a role of central adenosine mechanisms. Neurosci Lett 1982; 33: 147-151.
5. Barraco RA, el-Ridi MR, Parizon M. The adenosine analog, 5′-N-ethylcarboxamidoadenosine, exerts mixed agonist action on cardiorespiratory parameters in the intact but not decerebrate rat following microinjections into the nucleus tractus solitarius. Brain Res 1990; 530: 54-72.
6. Eldridge FL, Millhorn DE, Kiley JP. Antagonism by theophylline of respiratory inhibition induced by adenosine. J Appl Physiol 1985; 59: 1428-1433.
7. Schmidt C, Bellingham MC, Richter DW. Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized cat. J Physiol 1995; 483.3: 769-781.
8. Lawrence AJ, Krstew E, Jarrott B. Complex interactions between nitric oxide and adenosine receptors in the rat isolated nodose ganglion. Eur J Pharmacol 1997; 328: 83-88.
9. Kwong K, Hong JL, Morton RF, Lee LY. Role of pulmonary C fibers in adenosine-induced respiratory inhibition in anesthetized rats. J Appl Physiol 1998; 84: 417-424.
10. Hong JL, Ho CY, Kwong K, Lee LY. Activation of pulmonary C fibres by adenosine in anaesthetized rats: role of adenosine A1 receptors. J Physiol 1998; 508(1): 109-118.
11. McQueen DS, Ribeiro JA. Effect of adenosine on carotid chemoreceptor activity in the cat. Br J Pharmacol 1981; 74: 129-136.
12. Burki NK, Dale WJ, Lee LY. Intravenous adenosine and dyspnea in humans. J Appl Physiol 2005; 98: 180-185.
13. Morgan-Hughes NJ, Corris PA, Healey MD, Dark JH, McComb JM. Cardiovascular and respiratory effects of adenosine in humans after pulmonary denervation. J Appl Physiol 1994; 76: 756-759.
14. Walsh MP, Marshall JM. The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat. J Physiol 2006; 575(1): 277-289.
15. Eldridge FL, Millhorn DE, Kiley JP. Respiratory effects of a long-acting analog of adenosine. Brain Res 1984; 301: 273-280.
16. Howell LL, Morse WH, Spealman RD. Respiratory effects of xanthines and adenosine analogs in rhesus monkeys. J Pharmacol Exp Ther 1990; 254: 786-791.
17. 2A receptors modulate sleep state and breathing in fetal sheep. J Appl Physiol 2001; 91: 343-350.
18. 1 receptor binding in the dorsal vagal complex of hypertensive and normotensive rats. Brain Res 1998; 802: 61-68.
19. Schaddelee MP, Voorwinden HL, Groenendaal D, et al. Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships. Eur J Pharm Sci 2003; 20: 347-356.
20. Bissonnette JM, Hohimer AR, Knopp SJ. The effect of centrally administered adenosine on fetal breathing movements. Respir Physiol 1991; 84: 273-285.
21. 1 receptors. J Neurosci 1995; 15: 3458-3467.
22. Bisserbe JC, Pascal O, Deckert J, Maziere B. Potential use of DPCPX as probe for in vivo localization of brain A1 adenosine receptors. Brain Res 1992; 599: 6-12.
23. Dixon AK, Gubitz AK, Sirinathsinghji DJ, Richardson PJ, Freeman TC. Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol 1996; 118(6): 1461-1468.
24. Stella L, Berrino L, Maione S, de Novellis V, Rossi F. Cardiovascular effects of adenosine and its analogs in anaesthetized rats. Life Sci 1993; 53: 755-763.
25. Schindler CW, Karcz-Kubicha M, Thorndike EB, et al. Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2 subtype receptor agonists. Br J Pharmacol 2005; 144: 642-650.
26. Shryock JC, Belardinelli L. Adenosine and adenosine receptors in the cardiovascular system: biochemistry, physiology, and pharmacology. Am J Cardiol 1997; 79(12A): 2-10.