Toxicity of copper(I)-NHC complexes against human tumor cells: Induction of cell cycle arrest, apoptosis, and DNA cleavage

Chemistry - A European Journal

Volumn 15, Issue 2, 2009, Pages 314-318

  Teyssot, Marie Laure ^a   Jarrousse, Anne Sophie ^a   Chevry, Aurélien ^a   De Haze, Angélique ^a   Beaudoin, Claude ^a   Manin, Michèle ^a   Nolanilvia, Steven P ^b   Diez Gonzalez ^b   Morel, Laurent ^a   Gautier, Arnaud ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA ICIQ   (Spain)

Author keywords

Antitumor agents; Apoptosis; Carbenes; Cell cycle

Indexed keywords

CELL CULTURE; CELL DEATH; COPPER; COPPER COMPOUNDS; DNA; GENES; LIGANDS; NUCLEIC ACIDS; ORGANIC ACIDS; PALLADIUM; PLATINUM COMPOUNDS; SILVER; SILVER COMPOUNDS; TUMORS;

ANTITUMOR AGENTS; APOPTOSIS; BREAST TUMORS; CARBENE LIGANDS; CARBENES; CELL CYCLE; CELL CYCLE ARREST; CELL-CYCLE PROGRESSION; CISPLATIN (CDDP); DNA CLEAVAGE; HUMAN TUMOR CELLS; MCF 7 CELLS; NUCLEASE ACTIVITY; PROTEIN KINASE (PKA);

PALLADIUM COMPOUNDS;

CARBENE; COPPER; DRUG DERIVATIVE; HETEROCYCLIC COMPOUND; LIGAND; METHANE; ORGANOMETALLIC COMPOUND;

APOPTOSIS; ARTICLE; CELL CYCLE; CHEMISTRY; DNA CLEAVAGE; DRUG EFFECT; HUMAN; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; COPPER; DNA CLEAVAGE; HETEROCYCLIC COMPOUNDS; HUMANS; LIGANDS; METHANE; ORGANOMETALLIC COMPOUNDS;

EID: 58449107632     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200801992     Document Type: Article

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