The expression of integrinβ1 and FAK in pituitary adenomas and their correlation with invasiveness

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 28, Issue 5, 2008, Pages 572-575

  Wang, Feng ^a   Shu, Kai ^a   Lei, Ting ^a   Xue, Delin ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Focal adhesion kinase; Integrin; Invasiveness; Pituitary adenoma

Indexed keywords

BETA1 INTEGRIN; FOCAL ADHESION KINASE 1; PTK2 PROTEIN, HUMAN;

ADENOMA; ADOLESCENT; ADULT; AGED; ARTICLE; CANCER INVASION; FEMALE; GENETICS; HUMAN; HYPOPHYSIS TUMOR; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION;

ADENOMA; ADOLESCENT; ADULT; AGED; ANTIGENS, CD29; FEMALE; FOCAL ADHESION KINASE 1; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PITUITARY NEOPLASMS; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 58449103908     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-008-0518-6     Document Type: Article

References (16)

1. I. M. Hussaini C. Trotter Y. Zhao 2007 Matrix metalloproteinase-9 is differentially expressed in nonfunctioning invasive and noninvasive pituitary adenomas and increases invasion in human pituitary adenoma cell line Am J Pathol 170 1 356 365
2. L. J. Kornberg 1998 Focal adhesion kinase and its potential involvement in tumor invasion and metastasis Head Neck 20 8 745 752
3. Y. T. Huang L. T. Lee P. P. Lee 2005 Targeting of focal adhesion kinase by flavonoids and small-interfering RNAs reduces tumor cell migration ability Anticancer Res 25 3B 2017 2025
4. G. B. Schneider Z. Kurago R. Zaharias 2002 Elevated focal adhesion kinase expression facilitates oral tumor cell invasion Cancer 95 12 2508 2515
5. A. N. Martins G. J. Hayes L. G. Kempe 1965 Invasive pituitary adenomas J Neurosurg 22 268 276
6. B. W. Scheithauer K. T. Kovacs E. R. Laws 1986 Pathology of invasive pituitary tumors with special reference to functional classification J Neurosurg 65 733 744
7. E. Knosp E. Steiner K. Kitz 1993 Pituitary adenomas with invasion of the cavernous sinus space: A magnetic resonance imaging classification compared with surgical findings Neurosurgery 33 4 610 618
8. J. P. Cottier C. Destrieux L. Brunereau 2000 Cavernous sinus invasion by pituitary adenomas: MR imaging Radiology 215 2 463 469
9. W. R. Selman E. R. Laws Jr B. W. Scheithauer 1986 The occurrence of dural invasion in pituitary adenomas J Neurosurg 64 402 407
10. H. H. Oruckaptan O. Senmevsim O. E. Ozcan 2000 Pituitary adenomas: results of 684 surgically treated patients and review of the literature Surg Neurol 53 3 211 219
11. M. Tamura J. Gu H. Tran 1999 PTEN gene and integrin signaling in cancer J Natl Cancer Inst 91 21 1820 1828
12. M. R. Farnoud N. Veirana P. Derome 1996 Adenomatous transformation of the human anterior pituitary is associated with alterations in integrin expression Int J Cancer 67 1 45 53
13. J. T. Parsons K. H. Martin J. K. Slack 2000 Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement Oncogene 19 5606 5613
14. V. Carloni A. Mazzocca P. Pantaleo 2001 The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells Hepatology 34 1 42 49
15. G. Jones J. Machado Jr M. Tolnay 2001 PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK) Cancer Res 61 15 5688 5691
16. F. Wan T. Lei K. Shu 2005 The role of integrinβ1 and focal adhesion kinase in the invasive behavior of pituitary adenomas in vitro Chin J Exp Surg (Chinese) 22 4 21 23